Performance of different osteosynthesis materials in microvascular fibula free flap reconstruction

Nobis, Christopher-Philipp; Lutz, Rainer; Weber, Manuel; Preidl, Raimund; Goetze, Elisabeth; Frohwitter, Gesche; Kesting, Marco

doi:10.1016/j.bjoms.2021.10.013

Cited by 4 publications

(3 citation statements)

References 23 publications

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“…This is currently the only study that compares ex-house CAD/CAM-assisted mandibular reconstruction with the partially adjustable ReconGuide system in a comparative pre-and postoperative fashion. Nobis et al recently demonstrated no superiority of any osteosynthesis material in mandibular reconstructive techniques (CAD/CAM vs. freehand vs. ReconGuide) regarding complications and bony consolidation rates (17). In our study, all plates were pre-bent 2.0 miniplates in both groups, as the ReconGuide method offers osteotomy-specific prebent 2.0 miniplates.…”

Section: Discussionmentioning

confidence: 46%

“…Nobis et al. recently demonstrated no superiority of any osteosynthesis material in mandibular reconstructive techniques (CAD/CAM vs. freehand vs. ReconGuide) regarding complications and bony consolidation rates ( 17 ). In our study, all plates were pre-bent 2.0 miniplates in both groups, as the ReconGuide method offers osteotomy-specific pre-bent 2.0 miniplates.…”

Section: Discussionmentioning

confidence: 99%

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Mandibular reconstructions with free fibula flap using standardized partially adjustable cutting guides or CAD/CAM technique: a three- and two-dimensional comparison

Weitz,

Grabenhorst,

Singer

et al. 2023

Front. Oncol.

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BackgroundMandibular reconstruction with the fibula free flap (FFF) is performed freehand, CAD/CAM-assisted, or by using partially adjustable resection/reconstruction aids. The two latter options represent the contemporary reconstructive solutions of the recent decade. The purpose of this study was to compare both auxiliary techniques with regard to feasibility, accuracy, and operative parameters.Methods and materialsThe first twenty consecutively operated patients requiring a mandibular reconstruction (within angle-to-angle) with the FFF using the partially adjustable resection aids between January 2017 and December 2019 at our department were included. Additionally, matching CAD/CAM FFF cases were used as control group in this cross-sectional study. Medical records and general information (sex, age, indication for surgery, extent of resection, number of segments, duration of surgery, and ischemia time) were analyzed. In addition, the pre- and postoperative Digital Imaging and Communications in Medicine data of the mandibles were converted to standard tessellation language (.stl) files. Conventional measurements – six horizontal distances (A–F) and temporo-mandibular joint (TMJ) spaces – and the root mean square error (RMSE) for three-dimensional analysis were measured and calculated.ResultsIn total, 40 patients were enrolled (20:20). Overall operation time, ischemia time, and the interval between ischemia time start until end of operation showed no significant differences. No significant difference between the two groups were revealed in conventional measurements of distances (A–D) and TMJ spaces. The Δ differences for the distance F (between the mandibular foramina) and the right medial joint space were significantly lower in the ReconGuide group. The RMSE analysis of the two groups showed no significant difference (p=0.925), with an overall median RMSE of 3.1 mm (2.2–3.7) in the CAD/CAM and 2.9 mm (2.2–3.8) in the ReconGuide groups.ConclusionsThe reconstructive surgeon can achieve comparable postoperative results regardless of technique, which may favor the ReconGuide use in mandibular angle-to-angle reconstruction over the CAD/CAM technique because of less preoperative planning time and lower costs per case.

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Section: Discussionmentioning

confidence: 46%

Section: Discussionmentioning

confidence: 99%

Mandibular reconstructions with free fibula flap using standardized partially adjustable cutting guides or CAD/CAM technique: a three- and two-dimensional comparison

Weitz,

Grabenhorst,

Singer

et al. 2023

Front. Oncol.

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“…These sections can be taken from the fibula, radius, iliac crest, ribs, or scapula. The fibula is known to be the preferred donor site for mandibular reconstructions [ 34 ]. Clinical success is dependent on preoperative planning, technical skill, and post-operative monitoring [ 35 ].…”

Section: Treatment Methods For Critical-sized Defectsmentioning

confidence: 99%

Functional Approaches in Promoting Vascularization and Angiogenesis in Bone Critical-Sized Defects via Delivery of Cells, Growth Factors, Drugs, and Particles

Shineh

Patel

Mobaraki

et al. 2023

JFB

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Critical-sized bone defects, or CSDs, are defined as bone defects that cannot be regenerated by themselves and require surgical intervention via employing specific biomaterials and a certain regenerative strategy. Although a variety of approaches can be used to treat CSDs, poor angiogenesis and vascularization remain an obstacle in these methods. The complex biological healing of bone defects depends directly on the function of blood flow to provide sufficient oxygen and nutrients and the removal of waste products from the defect site. The absence of vascularization can lead to non-union and delayed-union defect development. To overcome this challenge, angiogenic agents can be delivered to the site of injury to stimulate vessel formation. This review begins by introducing the treatment methods for CSDs. The importance of vascularization in CSDs is subsequently highlighted. Delivering angiogenesis agents, including relevant growth factors, cells, drugs, particles, cell secretion substances, their combination, and co-delivery to CSDs are fully explored. Moreover, the effects of such agents on new bone formation, followed by vessel formation in defect areas, are evaluated.

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Patient-specific 3D-printed mini-versus reconstruction plates for free flap fixation at the mandible: Retrospective study of clinical outcomes and complication rates

Kreutzer,

Lampert,

Doll

et al. 2023

Journal of Cranio-Maxillofacial Surgery

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Performance of different osteosynthesis materials in microvascular fibula free flap reconstruction

Cited by 4 publications

References 23 publications

Mandibular reconstructions with free fibula flap using standardized partially adjustable cutting guides or CAD/CAM technique: a three- and two-dimensional comparison

Mandibular reconstructions with free fibula flap using standardized partially adjustable cutting guides or CAD/CAM technique: a three- and two-dimensional comparison

Functional Approaches in Promoting Vascularization and Angiogenesis in Bone Critical-Sized Defects via Delivery of Cells, Growth Factors, Drugs, and Particles

Patient-specific 3D-printed mini-versus reconstruction plates for free flap fixation at the mandible: Retrospective study of clinical outcomes and complication rates

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