Performance of CardioCel in Cardiac Surgery: A Systematic Review

Abstract

A systematic review was performed for evaluation of the performance of CardioCel® in cardiac surgery. The review included all studies published from January 2013 to December 2020. We conclude that CardioCel is a strong, flexible tissue substitute with good handling characteristics and a low incidence of thrombosis, aneurysm formation, infection, or structural degeneration. It can be used for a variety of intracardiac and extracardiac repairs of congenital heart defects in all age groups with good durability at mid-term follow-up. However, the use of CardioCel in certain positions requires caution. Information on the long-term performance of CardioCel is lacking.

Invited Commentary: Cardiocel® Patch: A Biological Tissue for Cardiac Repair, Not a Bioscaffold. Best Indications in Congenital Heart Surgery

“…Patukale et al 1 reported a systematic review of the published papers on the use and performance of CardioCel ® surgery. This ADAPT ® treated bovine pericardial patch is claimed to be a flexible and durable “scaffold,” which promotes tissue ingrowth claims while resisting degeneration, deformation, and calcification; therefore, reducing the need for reintervention.…”