Performance of 2016 revised fibromyalgia diagnostic criteria in patients with rheumatoid arthritis

Shresher, Nada Mahmoud; Mohamed, Aly Elsayed; Elshahaly, Mohsen

doi:10.1007/s00296-019-04403-8

Cited by 19 publications

(20 citation statements)

References 44 publications

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“…This questionnaire has been previously used to measure severity of bromyalgia, the prototypical centralized pain condition, in the general population as well as in disease-speci c cohorts, including the CPIRA cohort. 1,19 Statistical analysis Descriptive statistics were used to evaluate demographic and clinical data. The primary analysis evaluated the Spearman correlation between each QST measure (PPT, TS, CPM) and overall FSQ score.…”

Section: Assessment Of Bromyalgia Severitymentioning

confidence: 99%

Correlation of Fibromyalgia Survey Questionnaire and Quantitative Sensory Testing Among Patients With Active Rheumatoid Arthritis

et al. 2022

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Objective Patients with rheumatoid arthritis (RA) commonly demonstrate disordered pain processing, associated with high pain sensitization. Pain sensitization is often assessed using quantitative sensory testing (QST), which is burdensome to patients. The self-administered fibromyalgia survey questionnaire (FSQ) has been proposed as a low-burden, surrogate measure of central pain sensitization. We examined the correlation between FSQ and QST in patients with active RA. Methods Participants in the Central Pain in Rheumatoid Arthritis (CPIRA) cohort underwent FSQ and QST evaluation at enrollment. QST measures included pressure pain threshold (PPT) at the thumb, trapezius, wrist and knee; temporal summation (TS) at the wrist and arm; and conditioned pain modulation (CPM). Partial Spearman correlation between FSQ and each QST measure was assessed, adjusted for demographic factors, study site, disease characteristics, and pain catastrophizing. Sensitivity analyses included a) stratified analysis by sex and b) evaluation of how each component of FSQ associates with the QST measures. Results Among 285 participants with active RA, FSQ was weakly but statistically significantly correlated with PPT ( r = -0.21 to -0.31), and TS ( r = 0.13 to 0.15) at all sites in unadjusted analyses. After adjustment, statistically significant correlations persisted for PPT at all sites except the thumb, and for TS at the wrist. Sensitivity analyses did not identify differences in association based on sex or with individual FSQ components. Conclusion FSQ and QST were correlated among participants with active RA, but the strength of association was weak. QST and FSQ are not interchangeable measures of pain sensitization.

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Section: Assessment Of Bromyalgia Severitymentioning

confidence: 99%

Correlation of Fibromyalgia Survey Questionnaire and Quantitative Sensory Testing Among Patients With Active Rheumatoid Arthritis

et al. 2022

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“…54 Shresher et al studied 130 women with rheumatoid arthritis of which 40% met diagnostic criteria for fibromyalgia and in turn this group of patients had a longer duration of the disease, more pain measured using VAS and greater disease activity measured by DAS28, CDAI in comparison to patients without fibromyalgia. 55 Chronic inflammation creates a transition from peripheral pain to central pain that is perceived as fibromyalgia symptoms. Pro-inflammatory cytokines TNF and IL-6 have been identified as involved in central pain processing and increased generalized sensitivity.…”

Section: Obesity and Ramentioning

confidence: 99%

“…Pro-inflammatory cytokines TNF and IL-6 have been identified as involved in central pain processing and increased generalized sensitivity. 55 The impact of fibromyalgia in patients with RA is important, since it has been shown that patients with fibromyalgia and RA have more depressive episodes, anxiety, panic attacks and post-traumatic stress than those patients with only RA. [56][57][58] Pain is the most important independent factor together with the perception of disease activity in these patients.…”

Section: Obesity and Ramentioning

confidence: 99%

Beyond Rheumatoid Arthritis Evaluation: What are We Missing?

Espinoza¹,

Maldonado²,

Narvaez³

et al. 2021

OARRR

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Rheumatoid Arthritis (RA) is a chronic inflammatory autoimmune systemic disease that preferentially affects small and large joints with a progressive course and can become deforming and disabling. In recent years, much progress has been made in the evaluation of inflammation and disease activity, however, there are other factors that have a high impact on the quality of life of these patients, such as depression, anxiety, fatigue, sleep disorders, suicidal behavior, fibromyalgia, sexual activity, sarcopenia, frailty, cachexia and obesity that are not always evaluated by rheumatologists. This review shows that the evaluation and timely detection of these aspects in patients with RA could interfere with the prognosis and improve their quality of life.

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“…Furthermore, depressive disorders are three times more common in FM patients than in the general population [42] and FM patients show a higher incidence of depression than people with other chronic pain disorders [43]. In RA, proinflammatory cytokines including TNF and IL-6 have been implicated in central sensitization and the development of FM [44].…”

Section: Discussionmentioning

confidence: 99%

Screening for depressive symptoms in patients with rheumatoid arthritis: relationship with pain severity, disease activity, and sleep quality

Azzam

Lamlom

Khalifa

2022

Middle East Curr Psychiatry

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Background Rheumatoid arthritis (RA) is an autoimmune systemic condition that primarily affects all synovial joints, eventually leading to deformity and clinical disability. Much progress has been made in the evaluation of inflammation and disease activity in recent years; however, other factors that can influence these patients’ quality of life, including depression, stress, fatigue, sleep problems, fibromyalgia, sexual activity, and obesity, are often not evaluated by rheumatologists. Our purpose was to explore depressive symptoms in patients with RA and determine how they connected to other aspects of the disease, including pain severity, disease activity, and sleep quality. Results A cross-sectional study including 1200 patients with RA was performed. Paints with RA were classified into two groups based on the presence or absence of depressive symptoms using the Beck Depression Inventory-II (BDI-II). Group 1 included patients with both RA and depressive symptoms of varying severity; group 2 included patients with RA but without depressive symptoms. The patients underwent clinical evaluation and application of the Pittsburgh Sleep Quality Index (PSQI), Health Assessment Questionnaire for pain (HAQ-pain), and the Multidimensional Assessment of Fatigue scale (MAF). RA disease activity was evaluated using the DAS28 score. Depressive symptoms of varying severity were prevalent in 96% of our patients with RA, of whom 43.3% had minimal depression, while 13.7% had severe depression. The RA group with depression had a longer duration of disease, prolonged morning stiffness, and high disease activity measured by the DAS28 score than patients with only RA. In RA patients with concomitant depression, pain, sleep, and fatigue scores were also worse. Conclusions The presence of depression among patients with RA was associated with worse DAS28, HAQ, PASQI, and fatigue scores. Screening and recognition of such psychosocial disorders may help patients achieve optimal disease control and a good outcome.

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Performance of 2016 revised fibromyalgia diagnostic criteria in patients with rheumatoid arthritis

Cited by 19 publications

References 44 publications

Correlation of Fibromyalgia Survey Questionnaire and Quantitative Sensory Testing Among Patients With Active Rheumatoid Arthritis

Correlation of Fibromyalgia Survey Questionnaire and Quantitative Sensory Testing Among Patients With Active Rheumatoid Arthritis

Beyond Rheumatoid Arthritis Evaluation: What are We Missing?

Screening for depressive symptoms in patients with rheumatoid arthritis: relationship with pain severity, disease activity, and sleep quality

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