Performance, haemato-biochemical indices and antioxidant status of growing rabbits fed on diets supplemented with Mucuna pruriens leaf meal

Abstract

<p>The effects of dietary <em>Mucuna pruriens</em> leaf meal (MLM) supplementation on rabbits’ performance, haemato-biochemical indices and antioxidant status outside their thermal neutrality zone (21 to 25°C) were evaluated. One hundred and twenty 35-d old crossbreed (Chinchilla×New Zealand) rabbits weighing 694±5 g were allotted to 4 treatments (30 rabbits/treatment; 3 rabbits/replicate). A basal diet (crude protein: 16.9%, crude fibre: 17.6%, digestible energy: 2671 kcal/kg) was divided into 4 equal portions i.e. diets 1, 2, 3 and 4, supplemented with 0, 4, 8 and 12 g MLM/kg, respectively, and pelleted. The average body weight in rabbits fed on diets 3 and 4 was higher compared to those fed on diet 1 (control) at 91 d of age (+228 and +262 g, respectively; P=0.01). Within 35 to 91 d, the average daily weight gain in rabbits fed on diets 3 and 4 was higher compared to those fed on the control diet (+4.1and +4.8 g/d, respectively; P=0.01). The dressing-out percentage of rabbits fed on diets 3 and 4 increased (P=0.05) compared to those fed the control diet. At 63 d and 91 d of age, the white blood cell level of rabbits fed on diet 4 increased significantly compared to those fed the control diet (+5.05×10<sup>9</sup> and +5.32×10<sup>9</sup>/L, respectively). At 63 and 91 d of age, the cholesterol level of rabbits fed on diets 3 (–1.0 and –1.16 mmol/L, respectively) and 4 (–1.10 and –1.21 mmol/L, respectively), were significantly lower compared to those fed on the control diet. The aspartate aminotransferase (AST) concentration in rabbits fed on diet 4 was reduced compared to those on control diet at 63 d of age (–33.68 IU/L; P=0.02). At 63 d and 91 d of age, compared to control, the activities of glutathione peroxidase in rabbits fed on diets 3 (+35.77 and +49.09 mg protein, respectively) and 4 (+54.52 and +55.02 mg protein, respectively) increased significantly, while catalase activities in rabbits fed diet 4 (+217.7 and +209.5 mg/g, respectively) also increased significantly. It could be concluded that dietary MLM supplementation enhanced the rabbits’ performance, reduced serum AST and cholesterol and improved the antioxidant status.</p>

Mucuna Seed Powder Supplementation Value on Broiler Chickens Performance, Antioxidant Enzymes, Meat Cholesterol, Peroxidation, and Serum Metabolites

“…The observed increase serum glutathione peroxidase and superoxide dismutase activities in the birds fed MSP diets further revealed the antioxidant properties of MSP and its potentials to improve the antioxidant status of the experimental birds. This result is in tandem with the report of Oloruntola et al, (2018) who reported increased antioxidant activities in rabbits fed mucuna leaf meal supplemented diets. The improved oxidative status observed in birds fed the MSP supplemented diets in this study could also be linked to the improved performance recorded in these same set of birds because oxidative stress has been reported as one of the important factors preventing tropical domestic animals from attaining their full growth potential (Jimoh, 2018).…”

“…These plants are rich in secondary plant metabolites with robust capacity to elicit antioxidant, antimicrobial, antiviral, and immune-modulatory effects in a biological system (Applegate et al, 2010). Application of phytogenics feed additives has been reported to enhanced body weight and feed efficiency (Reis et al, 2018, Flees et al, 2020, egg production (Sharma et al, 2020), improve carcass yield, gut integrity and meat quality (Reis et al, 2018;Oloruntola et al, 2018), boost reproductive performance, serum enzymatic and antioxidant activity (Reis et al, 2018;Oloruntola et al, 2019), and reduced intestinal bacterial pathogenicity and medicinal cost (Reis et al, 2018). One of such phytogenic feed additives is mucuna seed (Mucuna pruriens var.…”

Biochemical and Oxidative Stress Parameters of Broilers Fed Meal and Protein Isolate of <i>Mucuna pruriens</i> Seeds

“…Dietary supplementation of meal and protein isolate of Mucuna increased the activity of CAT in organs and plasma of birds, implying that free radical formation could be prevented in broilers by dietary meal and protein isolate supplementation. This observation suggests that dietary meal and protein isolate of Mucuna could contain substances that can act either by stimulating the synthesis of antioxidant enzymes or by preventing their denaturation or their inhibition by free radicals [41].…”

Dietary cassava peel meal, methionine, and multi-enzyme supplementation in rabbits’ nutrition: effect on growth, digestibility, and carcass traits

“…Although it was reported that animal could ingest sublethal doses of cyanide over an extended period without harm in terms of mortality due to rapid detoxification (Mengel, Kramer, Isert, & Friedberg, 1989), continuous or repeated exposure and subsequent accumulation of cyanide (toxin) in the body fluids, tissues, and organs of the animals for a long period of time (chronic exposure) may predispose the animal to oxidative stress (Lei et al, 2017) and subsequently caused negative effects on biological activities and compromised performance (Halliwell & Gutteridge, 1989;Oloruntola, Ayodele, Adeyeye, & Agbede, 2018) as recorded in this study. Also, the multi-enzyme supplementation's positive significant (P < 0.01; 0.05) influence on the weight changes of the growing rabbits could be due to improvement of nutrient utilization (Boguhn & Rodehutscord, 2010;Lukuyu et al, 2014;Yang et al, 2010) and possible breaking down of anti-nutritive fractions (Bimrew, 2014;Lukuyu et al, 2014) in the diets by enzyme complex in the multi-enzyme used in this study.…”