Performance evaluation of raytest ClearPET&amp;#x2212;, a PET scanner for small and medium size animals

Roldan, P. Sempere; Canadas, M.; Dietzel, O.; Pautrot, C.; Sarasola, I.; Wagner, A.

doi:10.1109/nssmic.2007.4436731

Cited by 9 publications

(7 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For the above reason, although performance characterization of both systems has been done separately [7] [8], the work presented here will compare them in the same conditions and following the recommendations of the new NEMA NU 4-2008 standard [9] created to evaluate small animal PET systems. The main interest of this work is to asses the influence of the design differences between these scanners, specifically the axial-shifted detectors [10] and the planar versus circular ring configuration.…”

Section: Small Animal Positron Emission Tomography (Pet) Ismentioning

confidence: 99%

“…Sensitivity is expressed as the rate, in counts per second, that true coincidence events are detected for a given source intensity and branching ratio; absolute sensitivity is the fraction of positron annihilation events detected as true coincidence events [7]. The same 22Na point source described previously was scanned in small position increments along the entire axial FOV.…”

Section: B Sensitivitymentioning

confidence: 99%

“…where RNEC,i,j Rt,i,j and RrOT,i,j are the NEC, trues and total count rates for each acquisition j and slice i (counts are obtained from the 2D sinogram of each axial slice that is formed after SSRB rebinning, see details in NEMA, section 4 [7]). Total counts (also known as prompts) are referred to the total valid coincidences stored by the system whereas true counts are estimated as the total counts minus the scattered and random coincidences.…”

Section: E Derenzo Phantom Imagesmentioning

confidence: 99%

See 2 more Smart Citations

Performance comparison of two commercial small animal PET scanners: ClearPETT and rPET-1T

Canadas

Embid

Lage

et al. 2008

2008 IEEE Nuclear Science Symposium Conference Record

View full text Add to dashboard Cite

Abstract-It is usually difficult to compare different designs of Positron Emission Tomography (PET) small-animal scanners because of the disparity of measurements protocols. In this work we compare two commercial PET scanners installed at ClEMAT (Madrid, Spain): the ClearPET and the rPET-I, using an assessment procedure that fulfilled the recommendations of the new NEMA NU 4-2008 standard to evaluate small animal PET systems, including spatial resolution, sensitivity, scatter fraction and count losses studies. The scanners evaluated have significant geometrical differences, like the axial field of view (110 mm on ClearPET versus 45.6 mm on rPET-l), the configuration of the detectors (one pair of planar blocks on rPET-I, versus whole ring detectors on ClearPET) and the use of an axial shift between ClearPET module detectors. Our experiments showed a FWHM (FOV center, averaged over the three axes) of 1.98 mm for the rPET-1 and 2.15 rom for the ClearPET, with a small variation across the transverse axis on both scanners «1 rom). The absolute sensitivity was 1.0% per detector pair for rPET-I and 4.70/0 for ClearPET. Regarding count losses studies, the obtained peak NEC rate is 73.4 kcps at 0.51 MBq/ml for the ClearPET and 29.2 kcps at 1.35 MBq/ml for the rPET-1, considering a NEMA mouse-like phantom.

show abstract

Section: Small Animal Positron Emission Tomography (Pet) Ismentioning

confidence: 99%

Section: B Sensitivitymentioning

confidence: 99%

Section: E Derenzo Phantom Imagesmentioning

confidence: 99%

See 1 more Smart Citation

Performance comparison of two commercial small animal PET scanners: ClearPETT and rPET-1T

Canadas

Embid

Lage

et al. 2008

2008 IEEE Nuclear Science Symposium Conference Record

View full text Add to dashboard Cite

show abstract

“…Axial resolution is better for the Vista than for the Inveon at an MRD of 79; however, for an MRD of 46 (which gives a better comparison with the smaller maximum LOR acceptance angle of 22.1° of the Vista), axial FWHMs are similar. For the ClearPET (Raytest) in the small-crystal ring configuration (diameter, 135 mm), FWHMs in all directions were reported as less than or equal to 1.3 mm in the [195]. These values are clearly better than those of the Inveon.…”

Section: A41 Spatial Resolutionmentioning

confidence: 92%

“…The Vista is characterized by peak sensitivities of 0.065, 0.040, and 0.021 for energy windows of 100-700, 250-700, and 400-700 keV, respectively [194]. Finally, the reported peak sensitivity for the ClearPET is 0.045 [195,196] for the small-diameter, full-ring configuration with an ΔE of 250-750 keV.…”

Section: Figure 3a5mentioning

confidence: 99%

Quantification in dynamic and small animal positron emission tomography

Disselhorst¹

View full text Add to dashboard Cite

show abstract

Detectors in Medicine and Biology

Lecoq¹

2020

Particle Physics Reference Library

View full text Add to dashboard Cite

The invention by Crookes at the end of the nineteenth century of a device called spinthariscope, which made use of the scintillating properties of Lead Sulfide allowed Rutherford to count α particles in an experiment, opening the way towards modern dosimetry. When at the same time Wilhelm C. Roentgen, also using a similar device, was able to record the first X-ray picture of his wife's hand 2 weeks only after the X-ray discovery, he initiated the first and fastest technology transfer between particle physics and medical imaging and the beginning of a long and common history. Since that time, physics, and particularly particle physics has contributed to a significant amount to the development of instrumentation for research, diagnosis and therapy in the biomedical area. This has been a direct consequence, one century ago, of the recognition of the role of ionizing radiation for medical imaging as well as for therapy. 20.1.1 Radiotherapy and Dosimetry The curative role of ionizing radiation for the treatment of skin cancers has been exploited in the beginning of the twentieth century through the pioneering work of some physicists and medical doctors in France and in Sweden. This activity has very much progressed with the spectacular developments in the field of accelerators,

show abstract

Performance evaluation of raytest ClearPET−, a PET scanner for small and medium size animals

Cited by 9 publications

References 8 publications

Performance comparison of two commercial small animal PET scanners: ClearPETT and rPET-1T

Performance comparison of two commercial small animal PET scanners: ClearPETT and rPET-1T

Quantification in dynamic and small animal positron emission tomography

Detectors in Medicine and Biology

Contact Info

Product

Resources

About