Among the global problems, facing humanity at the beginning of the third millennium is the lack of water and the degradation of water quality. Water continues to play an essential and predominant role in sustaining life, being indispensable, and having an intrinsic value, inestimable in money. Water, a natural element in the common heritage of all mankind, constitutes at the same time an economic and social right of any person. Population growth and the continuous industrialization necessary for the modernization of society have led to an increase in the need for water and implicitly in the volume of wastewater discharged into rivers and seas. If the wastewater were accumulated without being purified, the decomposition of the organic material contained would lead to the production of unpleasant odorous gases, and the pathogenic microorganisms existing in the wastewater would cause serious illnesses to people. The modern society developed in industrialized cities produces a large volume of wastewater containing a variety of pollutants, of which especially those generated by the industry are toxic to all living organisms and make it impossible to self-purify the watercourses into which the wastewater was discharged. The treatment of municipal and industrial wastewater is a necessity of contemporary society in permanent development. Based on the analysis of the environmental and energy efficiency of the selected wastewater treatment plant (WWT) with the mechanical and biological treatment of wastewater, it was found that the highest BOD5 concentration of 3,583 mg/L occurred before wastewater treatment. The work of WWT was characterized by variable efficiency of the treatment process, which was shown by fluctuations in the results of three chemical indices, including COD, P, and N. An increased average concentration of total nitrogen of 80 mg/L, occurred with an underestimated reduction of pollution at a level not exceeding 90%. Wastewater treatment processes are characterized by statistically significant differences in results. The energy consumption of 1.58 kWh/m3 associated with the increase in the treated wastewater, together with the increase in average N concentration of 80 mg/L, indicates the need to improve the process of removing nutrients from domestic and economic wastewater.