Performance du Parasympathetic Tone Activity (PTA) pour prédire la réactivité hémodynamique chez le chien anesthésié

Mansour, Christelle; Merlin, Tristan; Boselli, Emmanuel; Allaouchiche, Bernard; Bonnet-Garin, Jeanne-Marie; Junot, Stéphane

doi:10.1016/j.anrea.2015.07.412

Cited by 1 publication

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“…Therefore, observations of pain should be made consistently by the same person (14,31). These human factors have led to tools that evaluate the sympathetic-parasympathetic tone balance attracting special interest (18,32), as one of the first responses of an organism to surgical stress is an increase in sympathetic tone and a decrease in parasympathetic tone, which influences HRV (23,29).…”

Section: Discussionmentioning

confidence: 99%

Clinical use of the parasympathetic tone activity index as a measurement of postoperative analgaesia in dogs undergoing ovariohysterectomy

Hernández-Ávalos

Valverde

Ibancovichi-Camarillo³

et al. 2021

Journal of Veterinary Research

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Introduction While the current tools to assess canine postoperative pain using physiological and behavioural parameters are reliable, an objective method such as the parasympathetic tone activity (PTA) index could improve postoperative care. The aim of the study was to determine the utility of the PTA index in assessing postoperative analgaesia. Material and Methods Thirty healthy bitches of different breeds were randomly allocated into three groups for analgaesic treatment: the paracetamol group (GPARAC, n = 10) received 15 mg/kg b.w., the carprofen group (GCARP, n = 10) 4 mg/kg b.w., and the meloxicam group (GMELOX, n = 10) 0.2 mg/kg b.w. for 48 h after surgery. GPARAC was medicated orally every 8 h, while GCARP and GMELOX were medicated intravenously every 24 h. The PTA index was used to measure the analgaesia–nociception balance 1 h before surgery (baseline), and at 1, 2, 4, 6, 8, 12, 16, 20, 24, 36, and 48 h after, at which times evaluation on the University of Melbourne Pain Scale (UMPS) was made. Results The baseline PTA index was 65 ± 8 for GPARAC, 65 ± 7 for GCARP, and 62 ± 5 for GMELOX. Postoperatively, it was 65 ± 9 for GPARAC, 63 ± 8 for GCARP, and 65 ± 8 for GMELOX. No statistically significant difference existed between baseline values or between values directly after treatments (P = 0.99 and P = 0.97, respectively). The PTA index showed a sensitivity of 40%, specificity of 98.46% and a negative predictive value of 99.07%. Conclusion Our findings suggest that the PTA index measures comfort and postoperative analgaesia objectively, since it showed a clinical relationship with the UMPS.

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