Performance comparison of single-view digital breast tomosynthesis plus single-view digital mammography with two-view digital mammography

Gennaro, Gisella; Hendrick, R. Edward; Ruppel, Patricia; Chersevani, Roberta; Maggio, C. Di; Grassa, Manuela La; Pescarini, Luigi; Polico, Ilaria; Proietti, Alessandro; Baldan, Enrica; Bezzon, Elisabetta; Pomerri, Fabio; Muzzio, Pier Carlo

doi:10.1007/s00330-012-2649-1

Cited by 44 publications

(26 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A subsequent study (112), comparing the combination of MLO-view DBT and CC-view FFDM with two-view FFDM in 469 breasts (68 with cancers) from 235 women, also reached a similar conclusion. A free-response study (113) with six readers interpreting 463 breasts, of which 258 had one or more lesions, including 77 malignancies in 68 breasts, reported statistically significant improvements in lesion detection and lesion characterization with the combination of MLO-view DBT and CC-view FFDM compared with two-view FFDM.…”

Section: Retrospective Multireader Multicase Studiesmentioning

confidence: 59%

Digital Breast Tomosynthesis: State of the Art

et al. 2015

View full text Add to dashboard Cite

This topical review on digital breast tomosynthesis (DBT) is provided with the intent of describing the state of the art in terms of technology, results from recent clinical studies, advanced applications, and ongoing efforts to develop multimodality imaging systems that include DBT. Particular emphasis is placed on clinical studies. The observations of increase in cancer detection rates, particularly for invasive cancers, and the reduction in false-positive rates with DBT in prospective trials indicate its benefit for breast cancer screening. Retrospective multireader multicase studies show either noninferiority or superiority of DBT compared with mammography. Methods to curtail radiation dose are of importance

show abstract

Section: Retrospective Multireader Multicase Studiesmentioning

confidence: 59%

Digital Breast Tomosynthesis: State of the Art

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Presumably, the general aim of the studies has been to use equivalent (or lower) absorbed dose levels to what is typically used in FFDM. As a consequence, when 1-view DBT has been the primary modality under investigation, similar total dose per examination has usually been used compared to that of FFDM [5,21,22,37]. Thereby, to a certain degree these may also have been adapted to dose levels typically used at a clinical center where a study was conducted.…”

Section: Discussionmentioning

confidence: 99%

Review of radiation dose estimates in digital breast tomosynthesis relative to those in two-view full-field digital mammography

et al. 2015

View full text Add to dashboard Cite

We examined how radiation dose levels in digital breast tomosynthesis (DBT) differ from those used in 2-view full-field digital mammography (FFDM). Acquisition parameter settings and information on the average absorbed dose to the glandular tissues within the breasts were reviewed based on clinical studies that evaluated DBT and FFDM. Dose ratios (DDBT/DFFDM) were derived from imaging protocols, which included tomosynthesis in 1- or 2-views alone, and as an adjunct technique to FFDM. Stand-alone DBT was associated with a much lower to a slightly higher radiation dose compared to that of comparable FFDM units, as summarized in dose ratio ranges of 0.34–1.0 for 1-view DBT, and 0.68 –1.17 for 2-view DBT. One of the lowest reported dose estimates was obtained using a photon-counting DBT unit (avg. 0.70 mGy/scan; range: 0.28–1.26 mGy). Breast doses for DBT combined with FFDM are summarized in dose ratio ranges of 1.03–1.5 for 1-view DBT plus FFDM, and 2.0–2.23 for 2-view DBT plus FFDM. In the latter of these settings, the dose was reduced by ∼45% when 2D-views, reconstructed from the DBT images (“synthetic 2D images”), were used as a substitute for FFDM. Stand-alone DBT operated at lower to slightly higher radiation doses in comparison to FFDM. For DBT combined with FFDM, radiation doses were elevated, at maximum by a factor ∼2 1/4 of that of FFDM alone. In this setting, a replacement of FFDM with synthetic 2D-views reduced the breast dose approximately by half, which has substantial implications for population screening programs.

show abstract

“…Regarding the goal of reducing radiation dose, there have been recent reports on the use of one-view DBT with or without FFDM (2,19,20). Because the primary objective of screening is improved cancer detection and we and others have previously observed a substantially larger improvement in cancer detection with the use of two-view DBT (6,9,15), we believe that the current lower-dose approach of synthesized 2D images plus DBT is more appropriate for screening purposes.…”

Section: Cancer Detectionmentioning

confidence: 91%

Two-View Digital Breast Tomosynthesis Screening with Synthetically Reconstructed Projection Images: Comparison with Digital Breast Tomosynthesis with Full-Field Digital Mammographic Images

Skaane¹,

Bandos²,

Eben³

et al. 2014

Radiology

289

158

View full text Add to dashboard Cite

show abstract

Performance comparison of single-view digital breast tomosynthesis plus single-view digital mammography with two-view digital mammography

Abstract: In this enriched study population, the combination of single-view MLO tomosynthesis plus single-view CC mammography was non-inferior to that of standard two-view digital mammography in terms of ROC curve area, sensitivity and specificity.

Cited by 44 publications

References 26 publications

Digital Breast Tomosynthesis: State of the Art

Digital Breast Tomosynthesis: State of the Art

Review of radiation dose estimates in digital breast tomosynthesis relative to those in two-view full-field digital mammography

Two-View Digital Breast Tomosynthesis Screening with Synthetically Reconstructed Projection Images: Comparison with Digital Breast Tomosynthesis with Full-Field Digital Mammographic Images

Contact Info

Product

Resources

About