Performance-based Measures of Visual Function

Warrian, Kevin; Altangerel, Undraa; Spaeth, George L.

doi:10.1016/j.survophthal.2009.06.006

Cited by 32 publications

(23 citation statements)

References 28 publications

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“…Although bilateral field evaluation might have advantages, at present, this is also not part of the EGS glaucoma classification. The best-eye criterion has been reported to be a good surrogate for binocular visual performance according to Warrian et al [22], who found that binocular visual acuity and better eye visual acuity show an exceptionally strong relationship (correlation coefficient = 0.9).…”

Section: Methodsmentioning

confidence: 99%

Health- and Vision-Related Quality of Life in Patients with Ocular Hypertension or Primary Open-Angle Glaucoma

et al. 2013

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Background: The main objective of this analysis was to assess the impact of severity of disease on the quality of life (QoL) of patients with ocular hypertension (OHT) and early, moderate, or advanced primary open-angle glaucoma (POAG). Methods: This multicenter study was conducted at 2 university hospitals and 13 ophthalmology practices in Germany. QoL data were assessed by the Health Utility Index (HUI3) and the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25). Results: 154 patients (17.5% OHT, 27.9% early, 22.7% moderate, and 31.8% advanced POAG) were included. The HUI3 scores for OHT, early, moderate, and advanced POAG were 0.87 ± 0.09, 0.85 ± 0.15, 0.75 ± 0.23, and 0.58 ± 0.32, respectively. Compared to a normal population matched by age and gender, for moderate and severe POAG a difference of -0.06 ± 0.24 and -0.19 ± 0.28, respectively, was observed. NEI-VFQ-25 scores illustrate different dimensions of the impact on QoL; reduced peripheral vision or difficulties to drive a car were more crucial to glaucoma patients than social factors. Conclusions: The key difference for QoL impairment in glaucoma lies between OHT/early POAG versus moderate/severe POAG, hence every possible effort needs to be made to prevent disease progression over this threshold.

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Section: Methodsmentioning

confidence: 99%

Health- and Vision-Related Quality of Life in Patients with Ocular Hypertension or Primary Open-Angle Glaucoma

et al. 2013

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“…For instance, the latter does not cover the whole visual spectrum but only the high spatial frequency and very high contrast ranges [7], and, therefore, a 20/20 result in visual acuity will not always uncover loss of vision for other contrasts and spatial frequencies. Hence, tests in low vision patients (patients with impaired eye sight that cannot be corrected by conventional means) often depend on self-reported changes in visual function and acuity, which can be highly inaccurate [2, 18]. The eye movement response can provide useful additional information, for instance, an extra dimension of data: that of response magnitude.…”

Section: Discussionmentioning

confidence: 99%

“…Loss of visual function can severely affect daily human activities and may effectively decrease the quality of life [1, 2]. Loss of vision can be caused by various ocular diseases, such as retinitis pigmentosa, macular degeneration [3], or glaucoma.…”

Section: Introductionmentioning

confidence: 99%

Human Gaze Following Response Is Affected by Visual Acuity

Spoor

Hosseini

Alphen

et al. 2014

Journal of Ophthalmology

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The present study investigated how gaze following eye movements are affected by stimulus contrast and spatial frequency and by aberrations in central visual acuity due to refractive errors. We measured 30 healthy subjects with a range of visual acuities but without any refractive correction. Visual acuity was tested using a Landolt-C chart. Subjects were divided into three groups with low, intermediate, or good visual acuity. Gaze following responses (GFR) to moving Gabor patches were recorded by video-oculography. In each trial, the subjects were presented with a single Gabor patch with a specific spatial frequency and luminance contrast that moved sinusoidally in the horizontal plane. We observed that GFR gain decreased with increasing spatial frequency and decreasing contrast and was correlated with visual acuity. GFR gain was lower and decreased more for subjects with lower visual acuity; this was especially so for lower stimulus contrasts that are not tested in standard acuity tests. The largest differences between the groups were observed at spatial frequencies around 4 cpd and at contrasts up to 10%. Aberrations in central visual acuity due to refractive errors affect the GFR response depending on the contrast and spatial frequency of the moving stimulus. Measuring this effect may contribute to a better estimate of changes in visual function as a result of aging, disease, or treatments meant to improve vision.

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“…Among these, the preservation and restoration of vision sufficient to allow individuals to function in their daily lives remains a central benchmark against which successful management can be measured. Performance-based measures (PBMs) of visual function involve standardised methods of assessing the ability to perform activities commonly encountered in daily life, under standardised conditions, using predetermined criteria 2. Although a growing body of literature has shed light on how to develop and employ PBMs to validly and reliably assess the impact of visual impairment on daily functioning, it is unknown which method to quantify such evaluations is optimal and much research remains to be conducted to refine these methods 3.…”

Section: Introductionmentioning

confidence: 99%