Performance Assessment of the GenoType®MTBDRplus Assay for Rapid Detection of Multidrug-Resistant Tuberculosis among Clinical Isolates in Low Tuberculosis Burden Setting

Abstract

Introduction: New molecular assays for rapid Multidrug-Resistant Tuberculosis (MDR-TB) detection continue to be developed. Rwanda has recently introduced the line probe assay for early TB and MDR-TB diagnosis. We aimed to assess the performance of GenoType ® MTBDRplus test before its implementation in the routine testing.