In this paper, non-orthogonal multiple access (NOMA) is designed and implemented for the fifth generation (5G) of multi-user wireless communication. Field-programmable gate array (FPGA) is considered for the implementation of this technique for two users. NOMA is applied in downlink phase of the base-station (BS) by applying power allocation mechanism for far and near users, in which one signal contains the superposition of two scaled signals depending on the distance of each user from the BS. We assume an additive white Gaussian noise (AWGN) channel for each user in the presence of the interference due to the non-orthogonality between the two users’ signals. Therefore, successive-interference cancellation (SIC) is exploited to remove the undesired signal of the other user. The outage probability and the bit-error rate performance are presented over different signal-to-interference-plus-noise ratio (SINR). Furthermore, Monte-Carlo simulations via Matlab are utilized to verify the results obtained by FPGA, which show exact-close match.