Perforating pilomatricoma—difficulty in diagnosis

Arnold, M.; McGuire, Lloyd

doi:10.1016/s0190-9622(88)80189-0

Cited by 24 publications

(8 citation statements)

References 6 publications

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“…Four clinical variants have been described: an eruptive type 6 ; a perforating type 7,8 ; a familial type associated with myotonic dystrophy 9 ; and a recurrent, invasive, nonmetastatic pilomatrix carcinoma 10 . We report a case of multiple pilomatricomas associated with myotonic dystrophy.…”

mentioning

confidence: 97%

Multiple Pilomatricomas and Myotonic Dystrophy

Street

Rogers

1991

The Journal of Dermatologic Surgery and Oncology

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confidence: 97%

Multiple Pilomatricomas and Myotonic Dystrophy

Street

Rogers

1991

The Journal of Dermatologic Surgery and Oncology

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“…Using Mehregan's original classification system, we reviewed previously reported cases of perforating pilomatricoma. In many patients, the pilomatricoma was complicated by an ulcer or thinned epithelia with damage to the epithelial structures (2, 5–7, 9, 10, 12, 13); such findings are not consistent with the original definition of transepithelial elimination at all.…”

Section: Discussionmentioning

confidence: 95%

“…Perforating pilomatricoma is a rare clinical entity. To the best of our knowledge, only 13 cases have been reported in the international medical literature (2, 5–13). In many of these reports, the histopathological term “transepithelial elimination” has been used (2, 7–11, 13).…”

Section: Discussionmentioning

confidence: 99%

“…Pilomatricoma, or calcifying epithelioma of Malherbe (1), is a dermal tumor that arises from primitive cells of the hair matrix. We report a case of perforating pilomatricoma, which is one of the clinical variants (2). In past studies of perforating pilomatricoma, a histopathological term, transepithelial elimination, has often been used quite differently from its original definition proposed by Mehregan in 1968 and 1970 (3, 4).…”

Section: Introductionmentioning

confidence: 99%

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Perforating Pilomatricoma: Transepithelial Elimination or Not

Honda

Koga

et al. 2002

The Journal of Dermatology

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We present a 56-year-old woman with a perforating pilomatricoma in the left eyebrow region. Histologically, the tumor consisted mainly of basophilic cells and shadow cells, and the tumor components were being eliminated through an ulcer with damage to the epithelial structures. In past reports of perforating pilomatricoma, this elimination pattern has often been described as transepithelial elimination. In many patients with perforating pilomatricoma, elimination is accompanied by ulceration and epithelial damage. Mehregan recently stated that elimination accompanied by epidermal necrosis and superficial ulceration constituted one form of transepithelial elimination. Epidermal necrosis and ulceration generally constitute severe damage. However, when Mehregan first proposed the concept of transepithelial elimination, it was defined as a phenomenon with relatively little or no damage to the epithelial structures, differentiating it from other types of elimination. This original definition makes transepithelial elimination a unique and interesting phenomenon, and its most important feature is that there is relatively little or no damage to the epithelial structures. Therefore, the terms "epidermal necrosis" and "ulceration" should not be used in association with transepithelial elimination. Hence, in patients with perforating pilomatricoma, the elimination of tumor components from ulcers with damage to the epithelial structures, as seen in the present case, should not be described as transepithelial elimination.

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“…It usually occurs as a single nodule with diameter of 0.5-3.0 cm, localized dermally or subcutaneously; however, sometimes multiple pilomatrixoma may occur [3,13,26]. It has four clinical variants: eruptive, perforating, familial associated with myotonic dystrophy, and a recurrent invasive, nonmetastatic pilomatrix carcinoma [2,5,14,24]. It is more commonly seen in Caucasians below the age of 20 and is more common in females than in males [19].…”

Section: Introductionmentioning

confidence: 99%

Giant pilomatrixoma

Askar

2002

European Journal of Plastic Surgery

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Pilomatrixoma is most commonly seen in the head and neck region, occurring in the first two decades of life. It varies from 0.5 cm to 3 cm in diameter. Pilomatrixoma differentiates toward hair cells. Treatment of choice is excision. A 42-year-old woman presented with a giant painful pilomatrixoma, 5 cm in diameter, in the forearm. It had gradually grown larger over a period of years. Physical examination revealed a painful, red-brown colored, ulcerative, mobile mass, 50 mm in diameter, with surrounding hyperemia. Histopathological examination of the specimen provided the diagnosis of "pilomatrixoma". The mass was totally excised, and the resultant tissue defect was repaired with a full-thickness skin graft from the inguinal area. Two years later, there was no recurrence and the postoperative scar was cosmetically acceptable. Generally, there is no recurrence if the pilomatrixoma is totally resected. The case presented in this paper is of interest because the lesion had a large diameter, appeared in the fourth decade, and had a "faceted stone" appearance with perforation of the overlying skin. It is important to differentiate this lesion from a pilomatrix carcinoma. Fig. 1 A 42-year-old woman with a painful, red-brown, ulcerative, mobile mass, 50 mm in diameter, with surrounding hyperemiaFig. 3 The 2-year postoperative result was cosmetically acceptable

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Perforating pilomatricoma—difficulty in diagnosis

Cited by 24 publications

References 6 publications

Multiple Pilomatricomas and Myotonic Dystrophy

Multiple Pilomatricomas and Myotonic Dystrophy

Perforating Pilomatricoma: Transepithelial Elimination or Not

Giant pilomatrixoma

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