Perfluoroalkyl substances (PFAS) in freshwater fish from urban lakes in Hanoi, Vietnam: concentrations, tissue distribution, and implication for risk assessment

Hòa, Nguyễn Thị; Lieu, Tran Thi; Anh, Hoang Quoc; Huong, Nguyen Thi; Nguyen, Trong-Nghia; Chuc, Nguyen Thi; Quang, Phan Dinh; Thi, Phung; Tuyến, Le Huu

doi:10.1007/s11356-022-19532-0

Cited by 21 publications

(3 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In Lebanon, fish is mostly imported—live, fresh, and frozen—from countries such as Turkey, Vietnam and Egypt [ 55 ]. In fact, PFAS was detected in these countries, specifically in air dust and food packaging in Egypt [ 56 ], in tap water in Turkey [ 57 ] and in freshwater fish in Vietnam [ 58 ], although levels were below the values considered safe/tolerable in all these studies. Moreover, another source—in Lebanon—that contributes to a lesser extent to fish production (mostly trout) is aquaculture, through family owned farms [ 55 ].…”

Section: Discussionmentioning

confidence: 99%

Maternal Serum, Cord and Human Milk Levels of Per- and Polyfluoroalkyl Substances (PFAS), Association with Predictors and Effect on Newborn Anthropometry

Mahfouz

Harmouche-Karaki

Matta

et al. 2023

Toxics

View full text Add to dashboard Cite

Background: The understanding of per- and polyfluoroalkyl substances (PFAS) health effects is rapidly advancing among critical populations. Therefore, the objective of this study was to assess PFAS serum levels among Lebanese pregnant women, cord serum and human milk levels, their determinants, and effects on newborn anthropometry. Methods: We measured concentrations of six PFAS (PFHpA, PFOA, PFHxS, PFOS, PFNA and PFDA) using liquid chromatography MS/MS for 419 participants, of which 269 had sociodemographic, anthropometric, environmental and dietary information. Results: The percentage of detection for PFHpA, PFOA, PFHxS and PFOS was 36.3–37.7%. PFOA and PFOS levels (95th percentile) were higher than HBM-I and HBM-II values. While PFAS were not detected in cord serum, five compounds were detected in human milk. Multivariate regression showed that fish/shellfish consumption, vicinity to illegal incineration and higher educational level were associated with an almost twice higher risk of elevated PFHpA, PFOA, PFHxS and PFOS serum levels. Higher PFAS levels in human milk were observed with higher eggs and dairy products consumption, in addition to tap water (preliminary findings). Higher PFHpA was significantly associated with lower newborn weight-for-length Z-score at birth. Conclusions: Findings establish the need for further studies, and urgent action to reduce exposure among subgroups with higher PFAS levels.

show abstract

Section: Discussionmentioning

confidence: 99%

Maternal Serum, Cord and Human Milk Levels of Per- and Polyfluoroalkyl Substances (PFAS), Association with Predictors and Effect on Newborn Anthropometry

Mahfouz

Harmouche-Karaki

Matta

et al. 2023

Toxics

View full text Add to dashboard Cite

show abstract

“…A study focused on fish filet samples [103] showed that from 2014 and 2019 a decrease of PFAS occurred, while PFOS increased. Hoa et al [104] deepened the study on fish by investigating distribution of PFAS contamination in the different tissues. The fish blood samples were found to be contaminated by 17 PFAS, with concentrations from 5.2 ng/mL to 29 ng/mL.…”

Section: Contamination Of Food and From Food Contact Materialsmentioning

confidence: 99%

PFAS: A Review of the State of the Art, from Legislation to Analytical Approaches and Toxicological Aspects for Assessing Contamination in Food and Environment and Related Risks

Schiavone

Portesi

2023

Applied Sciences

View full text Add to dashboard Cite

More than 7000 synthetic compounds known as per- and poly-fluoroalkyl substances (PFAS) are applied to food packaging and other materials to provide fat, fire, and/or water resistance properties. These compounds have exceptional environmental stability and persistence due to the strong C-F chemical bond, earning them the moniker “forever chemicals”. Emission of PFAS from industrial waste leads to water, air, and soil contamination. Due to this ubiquitous nature, combined with the fact that PFAS in humans are known to have carcinogenic and reprotoxic effects and to cause vaccine resistance and depression of the immunity system, PFAS may constitute a major threat to human health. For this reason, the attention of the scientific community and of control bodies is increasing and as a consequence legislation and the scientific literature on PFAS are constantly evolving. This review aims to provide a comprehensive overview of the state of the art about current legislation addressing PFAS; targeted and screening method for identification, detection and quantification of PFAS; toxicity of PFAS; and contamination of environmental and food matrices and from food contact matrices. A comprehensive review of the latest scientific research and recent developments in the legislation of PFAS will provide insights into the current understanding of PFAS and its health implications. Moreover, it will serve as a valuable reference for further studies related to PFAS and could help in informing future policy decisions.

show abstract

“…In addition, historical collections of tidal channel catfish ( Ictalurus punctatus ) and white perch ( Morone americana ) also had quantifiable detections of PFNA in fillets of 11 and 31 ng/g, respectively; although tissue concentrations have temporally decreased with decreasing surface water concentrations (MacGillivray, 2021). Importantly, muscle (or filets) is not the primary tissue for accumulation of many common PFAS; in fact, PFAS typically accumulate to higher concentrations in blood and liver compared with PFAS concentrations in muscle of freshwater fish (Hoa et al, 2022). For PFNA, Zhang et al (2012) found that liver concentrations were on average approximately 150 µg/g wet weight following zebrafish ( Danio rerio) exposures of 1 mg PFNA/L in the laboratory.…”

Section: Introductionmentioning

confidence: 99%

Ecotoxicity and Accumulation of Perfluorononanoic Acid in the Fathead Minnow (Pimephales promelas) and an Approach to Developing Protective Thresholds in the Aquatic Environment Through Species Sensitivity Distribution

Suski¹,

Chanov²,

Heron

et al. 2023

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

Per‐ and polyfluoroalkyl substances (PFAS) are ubiquitous in the environment. Locations where PFAS‐containing aqueous film‐forming foam (AFFF) has been used or accidentally released have resulted in persistently high concentrations of PFAS, including in surface water that may be adjacent to release sites. Perfluorooctane sulfonic acid (PFOS) is most frequently measured near AFFF release sites; however, other PFAS are being quantified more frequently and, of those, perfluorononanoic acid (PFNA) is common. The goal of our study was to fill data gaps on PFNA toxicity to freshwater fish using the fathead minnow (Pimephales promelas). We aimed to understand how PFNA may impact apical endpoints following a 42‐day exposure to mature fish and a 21‐day exposure to second‐generation larval fish. Exposure concentrations were 0, 124, 250, 500, and 1000 µg/L for both adult (F0) and larval (F1) generations. The most sensitive endpoint measured was development in the F1 generation at concentrations of ≥250 µg/L. The 10% and 20% effective concentration of the tested population for the F1 biomass endpoint was 100.3 and 129.5 µg/L, respectively. These data were collated with toxicity values from the primary literature on aquatic organisms exposed to PFNA for subchronic or chronic durations. A species sensitivity distribution was developed to estimate a screening‐level threshold for PFNA. The resulting hazard concentration protective of 95% of the freshwater aquatic species was 55 µg PFNA/L. Although this value is likely protective of aquatic organisms exposed to PFNA, it is prudent to consider that organisms experience multiple stressors (including many PFAS) simultaneously; an approach to understand screening‐level thresholds for PFAS mixtures remains an uncertainty within the field of ecological risk assessment. Environ Toxicol Chem 2023;00:1–8. © 2023 SETAC

show abstract

Perfluoroalkyl substances (PFAS) in freshwater fish from urban lakes in Hanoi, Vietnam: concentrations, tissue distribution, and implication for risk assessment

Cited by 21 publications

References 51 publications

Maternal Serum, Cord and Human Milk Levels of Per- and Polyfluoroalkyl Substances (PFAS), Association with Predictors and Effect on Newborn Anthropometry

Maternal Serum, Cord and Human Milk Levels of Per- and Polyfluoroalkyl Substances (PFAS), Association with Predictors and Effect on Newborn Anthropometry

PFAS: A Review of the State of the Art, from Legislation to Analytical Approaches and Toxicological Aspects for Assessing Contamination in Food and Environment and Related Risks

Ecotoxicity and Accumulation of Perfluorononanoic Acid in the Fathead Minnow (Pimephales promelas) and an Approach to Developing Protective Thresholds in the Aquatic Environment Through Species Sensitivity Distribution

Contact Info

Product

Resources

About