Perfluorinated compounds in fish from U.S. urban rivers and the Great Lakes

Stahl, Leanne L.; Snyder, Blaine D.; Olsen, A.R.; Kincaid, Thomas M.; Wathen, John B.; McCarty, Harry B.

doi:10.1016/j.scitotenv.2014.07.126

Cited by 93 publications

(56 citation statements)

References 51 publications

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“…Regarding PFCs in the Great Lakes region, there are fewer data available, partly because these chemicals have been in use for a shorter time compared with PCBs or PBDEs, but limited data suggest that the concentrations of many PFC congeners are increasing over time (Furdui et al, 2008). Recent data collected by the Environmental Protection Agency provide a baseline for future monitoring of PFC levels in the Great Lakes (Stahl et al, 2014); these data showed high detection frequency for certain PFCs including PFOS (100%), PFDA (92%), and PFUnA (90%). Thus, contaminants in Great Lakes fish remain a concern for consumers.…”

Section: Introductionmentioning

confidence: 99%

Levels of persistent contaminants in relation to fish consumption among older male anglers in Wisconsin

Christensen

Thompson

Werner

et al. 2016

International Journal of Hygiene and Environmental Health

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Fish are an important source of nutrients which may reduce risk of adverse health outcomes such as cardiovascular disease; however, fish may also contain significant amounts of environmental pollutants such as mercury, polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), and perfluorinated compounds (PFCs, also called perfluoroalkyl compounds), which confer increased risk for adverse health effects. The Wisconsin Departments of Health Services and Natural Resources developed a survey instrument, along with a strategy to collect human biological samples to assess the risks and benefits associated with long-term fish consumption among older male anglers in Wisconsin. The target population was men aged 50 years and older, who fish Wisconsin waters and live in the state of Wisconsin. Participants provided blood and hair samples and completed a detailed (paper) questionnaire, which included questions on basic demographics, health status, location of catch and species of fish caught/eaten, consumption of locally caught and commercially purchased fish, and awareness and source of information for local and statewide consumption guidelines. Biological samples were used to assess levels of PCBs, PBDEs, PFCs (blood), and mercury (hair and blood). Quantile regression analysis was used to investigate the associations between biomarker levels and self-reported consumption of fish from the Great Lakes and other areas of concern, other locally caught fish, and commercially purchased fish (meals per year). Respondents had a median age of 60.5 (interquartile range: 56, 67) years. The median fish consumption was 54.5 meals per year, with most fish meals coming from locally-caught fish. Participants had somewhat higher mercury levels compared with the US general population, while levels of other contaminants were similar or lower. Multivariate regression models showed that consumption of fish from the Great Lakes and areas of concern was associated with higher levels of each of the contaminants with the exception of PBDEs, as was consumption of locally caught fish from other water bodies. All commercial fish consumption was also associated with both hair and blood mercury. When looking at specific PCB, PBDE and PFC analytes, consumption of fish from the Great Lakes and areas of concern was associated with higher levels of each of the individual PCB congeners examined, as well as higher levels of all of the PFCs examined, with the exception of PFHxS. Among the PFCs, locally caught fish from other water bodies was also associated with higher levels of each of the congeners examined except PFHxS. Finally, all commercial fish was associated with higher levels of PFHxS.

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Section: Introductionmentioning

confidence: 99%

Levels of persistent contaminants in relation to fish consumption among older male anglers in Wisconsin

Christensen

Thompson

Werner

et al. 2016

International Journal of Hygiene and Environmental Health

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“…PFCAs with more than 9 carbon atoms have been also detected in fish (Stahl et al, 2014) and wildlife (Ahrens et al, 2009;Rubarth et al, 2011). These findings suggest that humans are also exposed to such PFCAs.…”

Section: Introductionmentioning

confidence: 86%

Disposition of perfluorododecanoic acid in male rats after oral administration

Kawabata

Tamaki

Kokubo

et al. 2017

Fundam. Toxicol. Sci.

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-The disposition of perfluorododecanoic acid (PFDoA), a perfluorocarboxylic acid with 12 carbon atoms, was studied in male rats. Rats received an oral administration of PFDoA at a dose of 50 mg/kg. The body weights of PFDoA-treated rats were slightly less than those of vehicle-treated control rats. PFDoA administration resulted in an increase in liver weight; it was highest at 5 days after the treatment and gradually decreased thereafter. Higher liver weight was observed until 70 days after the treatment. Concentrations of PFDoA in plasma and various tissues were estimated up to 70 days after dosing. A large amount of PFDoA was found in the liver. The PFDoA concentration was 263.94 ± 32.94 μg/g in the liver; the value was 7.93 times higher than that of serum 5 days after treatment. The hepatic PFDoA amount was found to be 29.63% of the dose. A certain amount of PFDoA was found in the brain and adipose tissues where perfluorocarboxylic acids with less than 11 carbon atoms were sparsely distributed. The half-life of PFDoA was 55.3, 49.3, 52.4, 57.1, and 49.8 days for serum, liver, kidneys, brain, and adipose tissue, respectively. PFDoA increased hepatic levels of mRNA for Cyp4A10, Acot1, and Acox1, target genes of PPARα, suggesting that PFDoA can activate PPARα, as was observed with other PFCAs. Elevated levels of these 3 genes were observed 70 days after treatment, and the levels were less than those at 7 days. The differences between PFDoA and PFCAs with less than 11 carbon atoms were discussed.

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“…4). Roczna wielkość produkcji PFOS na świecie oszacowana została w 2000 roku na poziomie 3500 ton, natomiast PFOA 1200 ton w 2004 roku [59]. W wyniku tego, substancje te są szeroko rozpowszechnione w środowisku naturalnym i najczęściej identyfikowane w osadach dennych i ściekowych, wodach powierzchniowych, gruntowych, deszczu, oraz faunie i florze [16].…”

Section: Ogólna Charakterystyka Perfluorowanych Związków Organicznychunclassified

Występowanie perfluorowanych związków organicznych w środowisku i fizykochemiczne metody usuwania ich z roztworów wodnych

2015

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Praca zawiera przegląd literatury dotyczący właściwości i występowania perfluorowanych związków organicznych w różnych komponentach środowiska oraz możliwości usuwania ich z roztworów wodnych w procesach fizykochemicznych. Związki perfluorowane stosowane są jako składniki wielu przedmiotów codziennego użytku. Wykazują one dużą trwałość i odporność termiczną i chemiczną. Stabilność perflurowanych związków organicznych, która wynika z ich struktury chemicznej powoduje, że są one obecne we wszystkich elementach środowiska. Wykazano ich obecność w wodzie, ściekach, glebie, żywności i kurzu domowym, a nawet we krwi ludzkiej i zwierzęcej. Podejrzenia, że związki te wpływają niekorzystnie na zdrowie człowieka i ulegają kumulacji w organizmie spowodowało zapoczątkowanie poszukiwań skutecznych metod, które pozwolą na wyeliminowanie ich na etapie oczyszczania wody czy ścieków. Okazuje się, że stopień usuwania w przypadku zastosowania konwencjonalnych metod często jest niewystarczający i znaczna część tych związków wprowadzana jest do śro-dowiska w niezmienionej formie albo w postaci bardziej toksycznych metabolitów. Procesy takie jak sorpcja, nanofiltracja czy odwrócona osmoza pomimo dobrej wydajności nie są wystarczające, ponieważ wymagają dalszych czynności w celu eliminacji wyodrębnionych związków. Dodatkowo właściwości perfluorowanych związków organicznych ograniczają ilość metod, które mogą być stosowane do ich eliminacji. Istnieje więc potrzeba opracowania nowych efektywnych sposobów ich usuwania oraz łączenia różnych technik w jednym procesie technologicznym.Słowa kluczowe: mikrozanieczyszczenia, związki endokrynnie aktywne, perfluorowane związki (PFCs), fizykochemiczne metody usuwania związków organicznych 1 Sabina Książek, Politechnika Rzeszowska, Katedra Inżynierii i Chemii Środowiska, Wydział Budownictwa, Inżynierii Środowiska i Architektury, 35-959 Rzeszów, al.

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Perfluorinated compounds in fish from U.S. urban rivers and the Great Lakes

Cited by 93 publications

References 51 publications

Levels of persistent contaminants in relation to fish consumption among older male anglers in Wisconsin

Levels of persistent contaminants in relation to fish consumption among older male anglers in Wisconsin

Disposition of perfluorododecanoic acid in male rats after oral administration

Występowanie perfluorowanych związków organicznych w środowisku i fizykochemiczne metody usuwania ich z roztworów wodnych

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