Perfil serológico de la infección por Helicobacter pylori en la población de San Luis (Argentina)

Mattana, Claudia Maricel; Vega, Alba Edith; Gómez, Patricia; Centorbi, Olga Puig de

doi:10.1016/s0213-005x(04)73071-2

Cited by 4 publications

(1 citation statement)

References 7 publications

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“…In a central region of Argentina, the percentage of H. pylori seropositive subjects, with or without gastric symptoms was not significantly different between groups of adults (80.2% and 75.9%, respectively), suggesting high-degree exposure to H. pylori in this population. 20 Among asymptomatic Japanese, who did not have cardiac disease or atherosclerosis, 45% were seropositive for the bacteria, 21 in contrast to 70.9% in healthy Korean adults. 22 From these observations we conclude: (1) nested PCR assay detected most of the H. pylori DNA in archived and fresh samples;…”

Section: Discussionmentioning

confidence: 99%

Seminested Polymerase Chain Reaction (PCR) for Detecting Helicobacter pylori DNA in Carotid Atheromas

Arias¹,

Martinetto²,

Schultz³

et al. 2006

Diagnostic Molecular Pathology

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A polymerase chain reaction (PCR) method for the detection of the glmM gene, selected as Helicobacter pylori target sequence, was improved. While performing pathogenicity island cagA gene detection to discriminate pathogenic strains in atherosclerotic carotid samples, several cagA-positive but glmM-negative samples were found. Polymorphisms present in the region amplified in the nested PCR reaction could explain this result; primers were therefore designed to perform a seminested reaction; this modification optimized sensitivity while maintaining specificity. A real-time PCR for Helicobacter DNA detection was also setup. The combination of all 4 PCR reactions detected 83% of H. pylori DNA-positive samples in atherosclerotic carotid tissue, 64% of which were cagA gene positive.

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Section: Discussionmentioning

confidence: 99%

Seminested Polymerase Chain Reaction (PCR) for Detecting Helicobacter pylori DNA in Carotid Atheromas

Arias¹,

Martinetto²,

Schultz³

et al. 2006

Diagnostic Molecular Pathology

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Prévalence de l’infection à Helicobacter pylori chez 103 patients avec reflux gastroœsophagien, œsophagite érosive ou un œsophage de Barrett à Yaoundé, Cameroun

Andoulo¹,

Kowo²,

Ngatcha³

et al. 2015

Hegel

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Introduction:The relationship between the Helicobacter pylori (H. pylori) infection and gastroesophageal reflux disease (GERD) is complex. Some epidemiological studies have suggested ap rotective role of the H. pylori infection in the development of GERD and its eradication would lead to the increase in GERD frequency. This article assesses the prevalence of the H. pylori infection among patients with GERD without injury, erosive esophagitis or Barrett's esophagus.Materials and methods: Between January and May 2015, 103 consecutive patients with daily or weekly GERD symptoms for at least one year were assessed at the Medical Center "la Cathédrale" of Yaoundé,C ameroon. All patients underwent anamnesis, physical examination, upper GI endoscopy with antral biopsies and rapid urease test HelicotecUT ® plus commercial kit (Strong Biotech Corp., Taipei, Taiwan). All statistical analyzes haveu sed the software Epi-Info 3.5.1 and the SPSS version 16.0 (IBM, Chicago, USA). Results:The study included 43 men and 60 women with an average ageo f4 6.5 ± 15.3y ears (range: 14-79 years). The prevalence of the H. pylori infection was 39.8% (95% CI: 30.4 to 49.3). H. pylori was positive in 34.6%o fp atients with erosive esophagitis against 41.6% in patients with endoscopy-negative GERD (p=0.533). Among the 41 H. pylori positive patients, only nine (22.0%) had erosive esophagitis, all of Savary-Miller grade 1. Conclusion:The prevalence of the H. pylori infection is low among the Cameroonian patients with GERD. Severe damage to the esophageal mucosa is rare among H. pylori positive patients comparedt oH. pylori negative ones. However, our data do not enable us have proof in defining the relationship between the H. pylori infection and GERD in our HP ylori endemic context. Further studies are awaited.

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Prevalence of Helicobacter pylori infection in the general adult population of the province of Ourense

García

Diz

Benavides

et al. 2006

Rev. esp. enferm. dig.

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Objectives: to determine the prevalence of Helicobacter pylori infection in the general adult population of the province of Ourense.Material and methods: a cross-sectional study was carried out with a randomly selected populational sample. The diagnosis of Helicobacter pylori infection was reached using the 13 C-urea breath test.Results: three hundred and eighty-three subjects were studied, with a prevalence rate of 69.1% (95% CI: 61.7-75.1%); 69.8% (95% CI: 63.2-76.6%) in males and 68.4% (95% CI: 61.5-75.4%) in females (difference not statistically significant). Prevalence increases with age up to a maximum of 88.4% in the 45-54 years age group, and decreases thereafter to a rate of 57.1% in individuals over the age of 84 years.Conclusion: this study reveals that the prevalence rate of Helicobacter pylori infection is high in the general adult population of the province of Ourense. It increases with age until it peaks in the group of middle-aged individuals and is similar in both sexes.

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Perfil serológico de la infección por Helicobacter pylori en la población de San Luis (Argentina)

Cited by 4 publications

References 7 publications

Seminested Polymerase Chain Reaction (PCR) for Detecting Helicobacter pylori DNA in Carotid Atheromas

Seminested Polymerase Chain Reaction (PCR) for Detecting Helicobacter pylori DNA in Carotid Atheromas

Prévalence de l’infection à Helicobacter pylori chez 103 patients avec reflux gastroœsophagien, œsophagite érosive ou un œsophage de Barrett à Yaoundé, Cameroun

Prevalence of Helicobacter pylori infection in the general adult population of the province of Ourense

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