Perfil metabólico de riesgo cardiovascular y resistencia a la insulina según índice de masa corporal, circunferencia de cintura y cintura hipertrigliceridémica en pacientes adultos

Z, Milagros Espinoza; F, Nelina Ruiz; Barrios, Emilia; Reigosa, Aldo; H, Ulises Leal; González, Julio César Rodríguez

doi:10.4067/s0034-98872009000900006

Cited by 9 publications

(6 citation statements)

References 27 publications

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“…Las concentraciones elevadas de glucosa realzan la secreción endotelial de endotelina 1 (ET-1), que altera el balance entre óxido nítrico (NO) y ET-1, favoreciendo la vasoconstricción y la disfunción endotelial en condiciones de resistencia a la insulina (RI) 38 . Esta última se refiere a un impedimento en la acción de la insulina en diversos tejidos 39 , causado por la disminución de la sensibilidad tisular que provoca un incremento compensatorio de la secreción de la hormona denominado hiperinsulinemia 40 .…”

Section: Cambios En La Formación De La Placa Aterosclerótica En Presencia De Diabetesunclassified

La diabetes y la alimentación determinantes en la progresión de aterosclerosis

Perales-Torres¹,

Castillo-Ruíz²,

Licón³

et al. 2016

Archivos de Cardiología de México

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The purpose of this review is to analyze the biochemical progression of atherosclerotic plaque and its association with diet and diabetes. This study shows the scientific evidence of demonstrating that diabetic patients present high levels of fatty acids like palmitic acid and linoleic acid in their atheroma plaques in comparison with non-diabetic patients. This study also establishes how patients with diabetes mellitus have a higher prevalence of atherosclerotic heart diseases in the form of Coronary Thrombosis and have different anatomopathological appearance like higher necrotic core and thin fibrotic layer than the general population. Furthermore this review describes the different anatomopathological appearance and cellular changes involved in the formation of these plaques and how diet can affect the development of these plaques.

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Section: Cambios En La Formación De La Placa Aterosclerótica En Presencia De Diabetesunclassified

La diabetes y la alimentación determinantes en la progresión de aterosclerosis

Perales-Torres¹,

Castillo-Ruíz²,

Licón³

et al. 2016

Archivos de Cardiología de México

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“…Therefore, widely used methods to evaluate the percentage of body fat and abdominal obesity include body mass index (BMI) (7) and waist circumference (WC) (8,9) . WC is a biometric measure that is used to determine centripetal obesity by measuring the accumulation of abdominal fat (10)(11)(12) .…”

Section: Introductionmentioning

confidence: 99%

“…However, from a clinical point of view, certain paradoxes exist. It is known, for example, that some patients may present a metabolic profile of normal risk, despite showing an excess of body fat, whereas others, with a moderate excess of weight, already present some metabolic complications (10,13,14) . Vague et al (14) observed already in 1947 that people with abdominal obesity developed cardiometabolic pathologies more frequently, compared with those who had peripheral obesity (10,15,16) .…”

Section: Introductionmentioning

confidence: 99%

“…It is known, for example, that some patients may present a metabolic profile of normal risk, despite showing an excess of body fat, whereas others, with a moderate excess of weight, already present some metabolic complications (10,13,14) . Vague et al (14) observed already in 1947 that people with abdominal obesity developed cardiometabolic pathologies more frequently, compared with those who had peripheral obesity (10,15,16) . Similarly, Crepaldi et al were one of the first to report the simultaneous presence of central obesity, hyperinsulinaemia, hypertriglyceridemia and hypertension (17) .…”

Section: Introductionmentioning

confidence: 99%

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Correlación entre medidas antropométricas, hipertensión arterial y glucosa en ayunas, en una población rural de Paraguay

Oviedo

Piris-Auada

Paniagua-Cristaldo

et al. 2020

Rev. Soc. cient. Parag.

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Antecedentes: el sobrepeso y la obesidad son importantes factores de riesgo de hipertensión y diabetes tipo 2. Además, imponen una carga significativa sobre el sistema nacional de salud. Objetivo: evaluar la correlación entre el índice de masa corporal (IMC) y la circunferencia de la cintura (CC) con la glucemia de glucosa en ayunas por presión arterial en residentes de la fracción Norma Luisa del municipio de Minga Guazú, Paraguay en 2013. Métodos: Estudio transversal que incluyó a 280 participantes entre 18 y 64 años, de la comunidad Norma Luisa del municipio de Minga Guazú, Paraguay, entre septiembre de 2012 y mayo de 2013. Resultados: en las cuatro categorías de IMC y WC, las diferencias entre los valores medios para la presión arterial sistólica y diastólica y la glucosa en ayunas fueron estadísticamente significativas (p <0.01). Hubo una correlación estadísticamente significativa entre los indicadores de IMC y WC con la presión arterial sistólica, diastólica y glucosa en ayunas. Además, hubo una correlación significativa entre el IMC y el WC. Conclusiones: Los resultados obtenidos mostraron que el IMC y el WC son predictores de hipertensión y aumento de la glucosa en ayunas. Estos estimadores pueden ayudar a establecer predicciones de morbilidad y mortalidad, tanto con fines clínicos como en el diseño de programas de intervención comunitaria para cambiar los hábitos de estilo de vida en la población local.

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“…There are several anthropometric parameters of diagnosis for MS. Among the most used is body mass index (BMI) [7], which is not considered a valid criterion because it does not reflect the distribution of body fat, although there are prediction formulas for total body fat [8]. The waist circumference (WC) is a non-invasive and straightforward measurement that has been shown to be a useful parameter to evaluate the distribution of body fat and cardiovascular risk as well as mortality from these events [9,10].…”

Section: Introductionmentioning

confidence: 99%

Probability and Body Composition of Metabolic Syndrome in Young Adults: Use of the Bayes Theorem as Diagnostic Evidence of the Waist-to-Height Ratio

Kammar

Hernández-Hernández

López-Moreno

et al. 2018

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Metabolic syndrome (MS) directly increases the risk of cardiovascular diseases. Childhood and adulthood have been the most studied in MS, leaving aside the young adult population. This study aimed to compare the epidemiological probabilities between MS and different anthropometric parameters of body composition. Using a cross-sectional study with the sample of 1351 young adults, different body composition parameters were obtained such as Waist Circumference (WC), Body Mass Index (BMI), Body Fat% (BF%), Waist-to-Height Ratio (WHtR), and Waist-Hip Ratio. The Bayes Theorem was applied to estimate the conditional probability that any subject developed MS with an altered anthropometric parameter of body composition. Areas under receiver operating characteristic curves (AUCs) and adjusted odds ratios of the five parameters were analyzed in their optimal cutoffs. The conditional probability of developing MS with an altered anthropometric parameter was 17% in WHtR, WC, and Waist-hip R. Furthermore, body composition parameters were adjusted by age, BMI, and gender. Only WHtR (OR = 9.43, CI = 3.4–26.13, p < 0.0001), and BF% (OR = 3.18, CI = 1.42–7.13, p = 0.005) were significant, and the sensitivity (84%) and the AUCs (86%) was higher in WHtR than other parameters. In young adults, the WHtR was the best predictor of metabolic syndrome.

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Perfil metabólico de riesgo cardiovascular y resistencia a la insulina según índice de masa corporal, circunferencia de cintura y cintura hipertrigliceridémica en pacientes adultos

Cited by 9 publications

References 27 publications

La diabetes y la alimentación determinantes en la progresión de aterosclerosis

La diabetes y la alimentación determinantes en la progresión de aterosclerosis

Correlación entre medidas antropométricas, hipertensión arterial y glucosa en ayunas, en una población rural de Paraguay

Probability and Body Composition of Metabolic Syndrome in Young Adults: Use of the Bayes Theorem as Diagnostic Evidence of the Waist-to-Height Ratio

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