Perfil lipídico en pacientes ingresados por síndrome coronario agudo en España: datos del área sanitaria de Toledo entre los años 2005 y 2008

Rodríguez-Roca, G.C.; Rodríguez‐Padial, Luis; Alonso-Moreno, F.J.; Romero-Gutiérrez, A.; Åkerström, Finn; Segura‐Fragoso, Antonio; Villarín-Castro, A.; Hernández-Moreno, J.; Menchén-Herreros, A; Gómez-Serranillos, Marta Sánchez; Artigao-Ródenas, Luis Miguel

doi:10.1016/j.semerg.2012.11.001

Cited by 5 publications

(1 citation statement)

References 15 publications

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“…But according to the literary data [7][8][9][10] the share of persons, in whom ACS developed on the background of normal rates of lipid metabolism is near 50 %, and they are mainly related to the groups of low and moderate cardiovascular risk according to SCORE, so at the initial link of medical-sanitary help this contingent is often left without proper attention and does not receive initial prophylaxis.…”

Section: Introductionmentioning

confidence: 99%

The Features of Atherosclerotic Process Development and Acute Coronary Syndrome Course in Patients Without Dyslipidemia

Vataha

2017

EUREKA: Health Sciences

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The aim is to study the conditions of appearance and the features of course of the acute coronary syndrome (ACS) in patients with normal rates of lipid metabolism and to assess the influence of additional risk factors (uinary acid, C-reactive protein, fibrinogen) on the development of atherosclerotic process by assessment of surrogate markers of atherosclerosis the thickness of intima-media complex (TIMC) of carotid arteries (СА), the presence of atherosclerotic plaque (AP) in CA, the value of ankle-brachial index (ABI)) in patients with ACS without dyslipidemia (DLP). Materials and methods. The study included 66 patients without DLP (50 men and 16 women, the mean age - 53,7±10,6 years) with ACS, divided in groups depending on its forms: 1 group – patients with instable angina (IA), 2 group – patients with myocardium infraction (MI) without ST segment elevation and 3 group – patients with MI with ST segment elevation. The level of serum acid, C-reactive protein, fibrinogen in blood serum were detected and ultrasound examination of СА with detection of CA TIMC, presence of atherosclerotic plaque and measuring of arterial pressure on upper and low extremities with ABI calculation was carried out. Results. Among examined patients MI with ST segment elevation was diagnosed in 33 persons (50,0%); MI without ST segment elevation – in 18 (27,3%) and IA – in 15 (22,7%). The complicated ACS was observed in 20 (30,30%) persons. The value of CA TIMC among patients with MI with ST segment elevation was reliably higher than in patients with MI without ST segment elevation (р<0,001), and ABI was reliably lower in persons with MI and ST segment elevation (р<0,05) and IA (р<0,05) than in patients with MI without ST segment elevation. Correlative analysis demonstrated the interconnection between the levels of inflammation indicators (C-reactive protein, fibrinogen) in the blood serum and the value of CA TIMC and ABI. Conclusions. The persons without DLP need additional examination (detection of C-reactive protein, fibrinogen levels in blood serum, ultrasound of CA and detection of ABI) for more precise evaluation of ACS risk.

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Section: Introductionmentioning

confidence: 99%

The Features of Atherosclerotic Process Development and Acute Coronary Syndrome Course in Patients Without Dyslipidemia

Vataha

2017

EUREKA: Health Sciences

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Prevalence, Treatment, and Control of Hypercholesterolemia in High Cardiovascular Risk Patients: Evidences from a Systematic Literature Review in Spain

et al. 2015

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IntroductionCardiovascular diseases (CVDs) represent a major Public Health burden. High serum cholesterol levels have been linked to major CV risk. The objectives of this study were to review the epidemiology of hypercholesterolemia in high risk CV patients from Spain, by assessing its prevalence, the proportion of diagnosed patients undergoing pharmacological treatment and the degree of attained lipid control.MethodsA systematic literature review was carried out using Medline and two Spanish databases. Manuscripts containing information on hypercholesterolemia in several high CV risk groups [diabetes mellitus (DM), Systematic COronary Risk Evaluation (SCORE) risk >5, or documented CVD], published between January 2010 and October 2014, were included.ResultsOf the 1947 published references initially retrieved, a full-text review was done on 264 manuscripts and 120 were finally included. Prevalence of hypercholesterolemia ranged from 50 to 84% in diabetics, 30–60% in patients with DM or elevated SCORE risk, 64–74% with coronary heart disease, 40–70% in stroke patients, and 60–80% in those with peripheral artery disease. Despite the finding that most of them were on pharmacological treatment, acceptable control of serum lipids was very variable, ranging from 15% to 65%. Among those with heterozygous familial hypercholesterolemia, 95–100% received treatment but less than 50% achieved their therapeutic goals.ConclusionsAn elevated prevalence of hypercholesterolemia can be found in targeted groups at high CV risk. Although most patients are receiving pharmacological treatment, rates of lipid control continue to be low, both in primary and secondary prevention.Electronic supplementary materialThe online version of this article (doi:10.1007/s12325-015-0252-y) contains supplementary material, which is available to authorized users.

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Lipid control in patients with coronary artery disease in a healthcare area in Cáceres (Spain): LIPICERES study

Gómez-Barrado

Ortiz

Gómez-Turégano

et al. 2017

Clínica e Investigación en Arteriosclerosis (English Edition)

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Perfil lipídico en pacientes ingresados por síndrome coronario agudo en España: datos del área sanitaria de Toledo entre los años 2005 y 2008

Cited by 5 publications

References 15 publications

The Features of Atherosclerotic Process Development and Acute Coronary Syndrome Course in Patients Without Dyslipidemia

The Features of Atherosclerotic Process Development and Acute Coronary Syndrome Course in Patients Without Dyslipidemia

Prevalence, Treatment, and Control of Hypercholesterolemia in High Cardiovascular Risk Patients: Evidences from a Systematic Literature Review in Spain

Lipid control in patients with coronary artery disease in a healthcare area in Cáceres (Spain): LIPICERES study

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