Percutaneous Vertebroplasty for Pregnancy-Associated Osteoporotic Vertebral Compression Fractures

Abstract

J Korean Neurosurg Soc 47 : [399][400][401][402] 2010 Osteoporosis is a worldwide problem and it mainly affects postmenopausal women. Osteoporosis associated with pregnancy or lactation is a rare condition. The incidence and mechanism of this phenomenon has not been clarified, but it can cause one or more vertebral compression fractures with severe, prolonged back pain in the affected women. We experienced this uncommon case, treated it with percutaneous vertebroplasty. A 35-old-woman visited our hospital with complaints of severe back pain and flank pain 2 months after normal vaginal delivery. She was diagnosed with osteoporotic vertebral compression fractures on the T5, 8, 9 and 11 vertebral bodies and we performed percutaneous vertebroplasty on the T8, 9 and 11 vertebrae with a good result. We present here an unusual case of pregnancy-associated compression fractures treated by percutaneous vertebroplasty.

ENDOCRINOLOGY IN PREGNANCY: Bone metabolic changes during pregnancy: a period of vulnerability to osteoporosis and fracture

“…Some initial experience with vertebroplasty has shown success in vertebral fractures (100,101). Hip fractures, in turn, require the surgical approach option that better suit the particular characteristics of the fracture.…”

Two cases of pregnancy- and lactation-associated osteoporosis successfully treated with denosumab

“…Reported treatment of this form of osteoporosis includes oral supplements of calcium and vitamin D, polar metabolites of this vitamin (calcitriol or alphacalcidol), calcitonin, bisphosphonates, teriparatide, and strontium ranelate (3,(13)(14)(15). In more severe cases, surgical intervention may be necessary (vertebroplasty, kyphoplasty, vertebral fusion) (16,17). There is no previous report on denosumab use in this situation in the literature.…”

Low Back Pain in Pregnancy: Investigations, Management, and Role of Neuraxial Analgesia and Anaesthesia: A Systematic Review

“…Axial loading of the spine may compress intervertebral discs, reduce disc height and cause disc protrusion culminating in radicular symptoms. Osteoporosis in pregnancy has been associated with vertebral [48] and sacral stress fractures [60] . Other rare pathologies may include osteomyelitis [99] and spinal tumours [91,100] .…”

“…Three case reports [47,48,50] and one literature review [91] described surgical management of vertebral fractures and vertebral hemangiomas respectively. Surgery was generally successful in relieving pain and restoring function without increased morbidity or mortality.…”