Percutaneous Vertebroplasty Does Not Increase the Incidence of New Fractures in Adjacent and Nonadjacent Vertebral Bodies

Yang, Wencheng; Liang, Ming

doi:10.1097/bsd.0000000000000734

Cited by 20 publications

(11 citation statements)

References 45 publications

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“…The incidence of postoperative re-fracture in the clinical studies included in the meta-analysis by Yu et al [ 10 ] was 3.21% to 63%, and the cumulative incidence was 10.3%. Yang et al [ 15 ] compared and analyzed 290 cases of PVP and 270 cases of OVCF who underwent conservative treatment. They were followed up for at least 24 months on average and found that the probability of recurring vertebral fractures after surgery was 12.8%.…”

Section: Discussionmentioning

confidence: 99%

RETRACTED ARTICLE: Analysis of risk factors related to the re-fracture of adjacent vertebral body after PKP

et al. 2021

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Background This study aims to investigate the risk factors of vertebral re-fracture after percutaneous kyphoplasty (PKP) for osteoporosis vertebral compression fracture (OVCF), and to provide reference for clinical prevention. Material and methods A retrospective analysis was performed on 228 OVCF patients admitted on November 6, 2013, solstice, December 14, 2018, which met the inclusion criteria. There were 35 males and 193 females, with a male-to-female ratio of 3:20, and an age of 61–89 years. All patients were treated with PKP surgery with complete clinical data, and the rate of re-fracture was calculated according to whether re-fracture occurred after surgery, divided into the re-fracture group (24 cases) and the non-refracture group (204 cases). May be associated with subsequent fracture factors (gender, age, number of surgical segment vertebral body, whether with degenerative scoliosis, whether to fight osteoporosis) into a single-factor research, then the single-factor analysis was statistically significant risk factors for multiple logistic regression analysis, further defined after PKP holds the vertebral body fracture independent risk factors. Survival analysis was performed using the time of vertebral re-fracture after PKP as the end time of follow-up, the occurrence of re-fracture after PKP as the endpoint event, and the presence or absence of degenerative lateral curvature as a variable factor. Results All 228 vertebroplasty patients were followed up for a period of 1.8 to 63.6 months. The mean follow-up time was (28.8 ± 15.6) months, and the re-fracture rate was 10.5%. There were statistically significant differences between the re-fracture group and the non-refracture group in age, number of operative vertebral bodies, whether there was a combination of degenerative scoliosis and whether there was anti-osteoporosis treatment (P < 0.05). The results of univariate logistic regression analysis after excluding the mutual influence of various factors showed that the number of vertebral bodies and the group with lateral curvature might be the risk factors for PKP re-fracture after surgery. The above possible risk factors were included in multiple logistic regression analysis to show whether there were independent risk factors for scoliosis and vertebral re-fracture. Survival analysis showed that the mean survival time was 42.1 months, the P value was 0.00, and the mean 95% confidence interval was (34.4–49.7 months), indicating that the combination of degenerative lateral bending might be related to the occurrence of re-fracture. Conclusions Combined scoliosis is an independent risk factor for re-fracture after OVCF laminoplasty and a possible risk factor for re-fracture after surgery.

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Section: Discussionmentioning

confidence: 99%

RETRACTED ARTICLE: Analysis of risk factors related to the re-fracture of adjacent vertebral body after PKP

et al. 2021

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“…It is believed as a safe and effective technique to release pain and improve functional status [14]. Although some authors declare that the incidence of new fractures in adjacent vertebrae may increase for the patients who were treated by PVP previously, it seems that it is osteoporosis rather that PVP that leads to new adjacent VCFs [15]. Considering the patient had undergone seven PVP, anti-osteoporosis therapy is the most important and appropriate management for this patient.…”

Section: Discussionmentioning

confidence: 99%

A Patient With Turner Syndrome Recieved the Percutaneous Vertebroplasty Seven Times: a Case Report and Literature Review

Li¹,

Shi²,

Zhao³

et al. 2021

Preprint

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Background Turner syndrome (TS) is characterized as the complete or partial absence of one X chromosome and is an extremely rare disease affecting approximately 1:2,500 live female births. Though the prevalence of osteoporosis among women with TS is estimated to be around 55-64% and they suffer more frequently from fractures than normal, few reports concerning TS patients with osteoporosis are able to be seen due to tiny number of patients. Case presentation Here we report a rare case of TS with osteoporosis, who has undergone percutaneous vertebroplasty (PVP) seven times because of several vertebral compression fractures (VCFs). G-banded karyotype analysis was performed and the result was 45,X[43]/47,XXX[17], indicating that the patient was a mosaicism of TS karyotype and Trisomy X syndrome karyotype. TS is the underlying cause of low level of estrogen for this patient. The interaction of aging, estrogen deficiency and intestinal dysbacteriosis leads to her severe osteoporosis and multi-segmental VCFs. The aim of this report is to provide recommendations regarding the management of TS patients with osteoporosis by reviewing the clinical presentation of TS, the influence of estrogen deficiency in osteoporosis, etc.Conclusions Early diagnosis and hormone replacement treatment are essential to prevent osteoporosis and reduce the risk of fractures. This is a rare case report describing TS patient with severe osteoporosis and VCFs.

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“…It is believed as a safe and effective technique to release pain and improve functional status [ 18 ]. Although some authors declare that the incidence of new fractures in adjacent vertebrae may increase for the patients who were treated by PVP previously, it seems that it is osteoporosis rather that PVP that leads to new adjacent VCFs [ 19 ]. The latest MRI suggested a suspected new fracture at T12.…”

Section: Discussionmentioning

confidence: 99%

A patient with Turner syndrome received the percutaneous vertebroplasty seven times: a case report and literature review

Shi

Zhao

et al. 2021

Eur J Med Res

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Background Turner syndrome (TS) is characterized as the complete or partial absence of one X chromosome and is an extremely rare disease affecting approximately 1:2500 live female births. Though the prevalence of osteoporosis among women with TS is estimated to be around 55–64% and they suffer more frequently from fractures than normal, few reports concerning TS patients with osteoporosis are able to be seen due to tiny number of patients. Case presentation Here, we report a rare case of TS with osteoporosis, who has undergone percutaneous vertebroplasty (PVP) seven times because of several vertebral compression fractures (VCFs). G-banded karyotype analysis was performed and the result was 45,X[43]/47,XXX[17], indicating that the patient was a mosaicism of TS karyotype and Trisomy X syndrome karyotype. TS is the underlying cause of low level of estrogen for this patient. The interaction of aging, estrogen deficiency and intestinal dysbacteriosis leads to her severe osteoporosis and multi-segmental VCFs. The aim of this report is to provide recommendations regarding the management of TS patients with osteoporosis by reviewing the clinical presentation of TS, the influence of estrogen deficiency in osteoporosis, etc. Conclusions Early diagnosis and hormone replacement treatment are essential for TS patients to prevent osteoporosis and reduce the risk of fractures. This is a rare case report describing TS patient with severe osteoporosis and VCFs.

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Percutaneous Vertebroplasty Does Not Increase the Incidence of New Fractures in Adjacent and Nonadjacent Vertebral Bodies

Cited by 20 publications

References 45 publications

RETRACTED ARTICLE: Analysis of risk factors related to the re-fracture of adjacent vertebral body after PKP

RETRACTED ARTICLE: Analysis of risk factors related to the re-fracture of adjacent vertebral body after PKP

A Patient With Turner Syndrome Recieved the Percutaneous Vertebroplasty Seven Times: a Case Report and Literature Review

A patient with Turner syndrome received the percutaneous vertebroplasty seven times: a case report and literature review

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