Percutaneous vertebroplasty and percutaneous balloon kyphoplasty for the treatment of osteoporotic vertebral fractures: a systematic review and cost-effectiveness analysis

Stevenson, Matt; Gomersall, Tim; Jones, Norman; Rawdin, Andrew; Alava, Mónica Hernández; Dias, Sofia; Wilson, David P.; Rees, Alan

doi:10.3310/hta18170

Cited by 89 publications

(74 citation statements)

References 227 publications

(906 reference statements)

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“…Among these, the following reviews were analyzed: three reviews comparing kyphoplasty versus vertebroplasty versus conservative treatment; 15-17 three reviews comparing kyphoplasty versus conservative treatment; [18][19][20] and six reviews comparing kyphoplasty and vertebroplasty. [17][18][19][21][22][23] Head-to-head comparisons of vertebroplasty versus kyphoplasty were the object of this analysis. Because there was an overlapping of the reviews above mentioned, the final number of studies evaluated was 9 (►Fig.…”

Section: Resultsmentioning

confidence: 99%

“…23 The authors identified nine randomized trials. Out of these, only one (Liu et al) directly compared kyphoplasty and vertebroplasty.…”

Section: Data Extractionmentioning

confidence: 99%

“…From a technical standpoint, kyphoplasty follows almost the same fluoroscopic principles used in vertebroplasty. [21][22][23][24][25][26][27][28][29][30] The aim of this study is to evaluate the effect of kyphoplasty, compared with that of vertebroplasty, for the treatment of osteoporotic vertebral fractures, based on an overview of published reviews.…”

Section: Introductionmentioning

confidence: 99%

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Effect of Kyphoplasty in the Treatment of Osteoporotic Vertebral Fractures Compared to Vertebroplasty – Overview of Systematic Reviews

et al. 2017

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Efeito da cifoplastia no tratamento de fraturas vertebrais osteoporóticas comparado ao da vertebroplastia -revisões das revisões sistemáticas publicadas AbstractIntroduction Vertebroplasty and kyphoplasty are possible options for vertebral augmentation after osteoporotic fractures. Both are percutaneous techniques with specific advantages and disadvantages. Our aim is to compare the clinical and radiological results of these two procedures. Methods An overview of published systematic reviews in the literature on the effects of kyphoplasty compared with vertebroplasty was performed. Results After short and long follow-up, the kyphoplasty group had lower pain scores on the visual analogue scale (VAS), lower scores in the Oswestry Disability index (ODI), greater restoration of the vertebral body height and lower kyphosis angle in the immediate postoperative period. There was less leakage of cement to the vertebral canal and extraspinal spaces. Conclusions Compared with vertebroplasty, kyphoplasty achieved better results in pain relief, quality of life, correction of spinal deformity and lower risk of cement leakage.

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Section: Resultsmentioning

confidence: 99%

“…23 The authors identified nine randomized trials. Out of these, only one (Liu et al) directly compared kyphoplasty and vertebroplasty.…”

Section: Data Extractionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effect of Kyphoplasty in the Treatment of Osteoporotic Vertebral Fractures Compared to Vertebroplasty – Overview of Systematic Reviews

et al. 2017

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“…68 In contrast, the National Institute for Health and Care Excellence, which provides evidence-based guidance and advice to the National Health Service in the United Kingdom examined the evidence to November 2011. 69 In April 2013, the National Institute for Health and Care Excellence recommended vertebroplasty and kyphoplasty as treatment options for patients with severe pain after a recent osteoporotic VCF and concluded that it was reasonable to assume that vertebroplasty and kyphoplasty reduce mortality. 70 Similarly, medical societies have also varied in their interpretations of the evidence.…”

Section: National Organization and Medical Society Opinionsmentioning

confidence: 99%

Vertebroplasty and Kyphoplasty for Osteoporotic Vertebral Fractures: What Are the Latest Data?

Chandra

Maingard

Asadi

et al. 2017

AJNR Am J Neuroradiol

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SUMMARY:Osteoporotic vertebral compression fractures frequently result in significant morbidity and health care resource use. For patients with severe and disabling pain, vertebral augmentation (vertebroplasty and kyphoplasty) is often considered. Although vertebroplasty was introduced Ͼ30 years ago, there are conflicting opinions regarding the role of these procedures in the treatment of osteoporotic vertebral compression fractures. This review article updates clinicians on the published prospective randomized controlled data, including the most recent positive trials that followed initial negative trials in 2009. Analysis of multiple national claim datasets has also provided further insight into the utility of these procedures. Finally, we considered the recent recommendations of national organizations and medical societies that advise on the use of vertebral augmentation procedures for osteoporotic vertebral compression fractures. ABBREVIATIONS:NRS ϭ numeric rating scale; PMMA ϭ polymethylmethacrylate; QUALEFFO ϭ Quality of Life Questionnaire of the European Foundation for

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“…6,15,16 However, there is still controversy around whether any of these treatments is more effective or safer in terms of the incidence of complications. 6,13,15,16,18 Another controversy revolves around comparing the effectiveness of and complications resulting from the use of one versus two portals. 5,6,16,19 For this reason, the objective of this study is to compare the results obtained and the incidence of complications from these two procedures in patients treated in our facility.…”

Section: Introductionmentioning

confidence: 99%

Kyphoplasty and Vertebroplasty in the Treatment of Osteoporotic Vertebral Fractures

García¹,

Ángel²,

Amado³

et al. 2018

Coluna/Columna

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Objective: To compare these procedures in the treatment of osteoporotic vertebral compression fractures. Methods: Patients who underwent vertebral augmentation procedures between March 2010 and October 2016 were selected for the study. Kyphosis, anterior vertebral height, Oswestry Disability Index (ODI), Visual Analog Scale (VAS), number of portals, cement volume, and complications were recorded. The results were analyzed by difference of the means. Results: Sixty-eight patients were selected, accounting for 105 procedures. A statistically significant improvement was observed in VAS and ODI with both procedures (p<0.001) without statistically significant difference between them, regardless of the number of portals or cement applied. There was a high correlation between kyphosis correction and ODI improvement (p=0.012). Conclusions: Both vertebroplasty and kyphoplasty are effective procedures for the treatment of vertebral compression fractures. We found no significant difference between both procedures. The high correlation between improvement of kyphosis and ODI suggests that these procedures are better than conservative treatment to improve the quality of life of patients, however more studies are required to reach a final conclusion.

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Percutaneous vertebroplasty and percutaneous balloon kyphoplasty for the treatment of osteoporotic vertebral fractures: a systematic review and cost-effectiveness analysis

Abstract: The National Institute for Health Research Health Technology Assessment programme.

Cited by 89 publications

References 227 publications

Effect of Kyphoplasty in the Treatment of Osteoporotic Vertebral Fractures Compared to Vertebroplasty – Overview of Systematic Reviews

Effect of Kyphoplasty in the Treatment of Osteoporotic Vertebral Fractures Compared to Vertebroplasty – Overview of Systematic Reviews

Vertebroplasty and Kyphoplasty for Osteoporotic Vertebral Fractures: What Are the Latest Data?

Kyphoplasty and Vertebroplasty in the Treatment of Osteoporotic Vertebral Fractures

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