Percutaneous Ventricular Restoration with a Partitioning Device for Ischemic Heart Failure Treatment

Abstract

PARACHUTE trials have shown >90% procedural success rate of VPD implant. Heart failure patients had improvement in hemodynamics (reduction in LV volumes and increase in LV ejection fraction) and functional status (6-min walking distance and quality of life scores) after the VPD implant. Optimal implant position is necessary to obtain a good clinical outcome. Percutaneous VPD implantation has thus far been a safe intervention capable of improving surrogate markers of heart failure but there is still a need to develop more durable devices with a long-lasting hemodynamics effect.

Structural Interventions in Heart Failure: Mending a Broken Heart

“…Initial trials of its use in 39 patients with ischemic cardiomyopathy, NYHA class II to IV symptoms, an LVEF between 15 to 40%, and dilated akinetic or dyskinetic anterior-apical walls showed an improvement or maintenance of NYHA functional class in 85% of patients, as well as improvement in LVEDVi (p = 0.0056) at 3-year follow up [21]. Results have been mixed across the PARACHUTE trials and more research is necessary to determine the safety and outcomes associated with these devices; a detailed review of the Parachute device can be found from Dhakal and Oliveira [55]. This Parachute device is not currently in use [53].…”

Conventional cardiac surgery in patients with end-stage coronary artery disease: yesterday and today

“…One of them, interventionallyimplanted endocardial Parachute device, first introduced in 2014, was shown to significantly reduce left ventricle volume, as well as to improve EF and functional NYHA class (25). In 2017, a review article summarizing previous experience with this novel device was published, showing quite high implantation success (over 90%) and promising postprocedural results in terms of reduction of LV volumes and improvement of EF (26). In 2019, an experience with hybrid ventricle restoration anchoring device, mimicking ventricular plication, was presented by 2 clinics from Netherlands.…”

Application of PICCO During Anesthesia of Patients Undergoing Transcatheter Ventricular Isolation Plasty Due to Left Ventricular Aneurysm

“…It is performed as follows: left ventricular (LV) angiography is carried out in patients with LVA and heart failure, followed by right femoral artery puncture for catheterization and installation of the isolation device. As an interventional treatment, this procedure can increase the LV ejection volume, change the ventricular structure to restore LV shape, improve cardiac function, and reduce clinical symptoms [Ige 2015] by isolating the infarcted and aneurysmal LV apex from the remainder of the cavity [Dhakal 2017]. Anesthesia plays an important role throughout the procedure [Evora 2014].…”