Of 47 consecutive patients referred for coronary angioplasty, the procedure was attempted in 13 patients despite occlusion of the involved vessel. This included four patients with total coronary occlusion and nine with functional coronary occlusion (faint, late antegrade opacification in the absence of a discernible luminal continuity). All procedures were performed with an angioplasty system in which the leading guide wire could be moved independently of the dilatation catheter. Primary success was obtained in 54% (7/13) of patients with coronary occlusion compared with 85% (29/34) in the remaining patients with conventional stenoses between 75% and 95% (91 + 5%, mean + SD; p < .02). In patients with coronary occlusion, the mean residual stenosis after angioplasty (41%), the abrupt reclosure rate (8%), and the incidence of angiographically evident dissection (29%) were similar to those seen in the 34 patients who underwent angioplasty of conventional stenoses, although restenosis tended to be more common (43% vs Received April 11, 1983; accepted June 2, 1983. This work was done during the tenure of a research fellowship from the American Heart Association, Greater Boston Massachusetts Division, No. 13-435-812 (J. P. D.).
776in totally occluded vessels.' Angioplasty systems in which the leading guide wire can be moved independently of the balloon catheter have recently been developed and offer advantages over fixed wire systems in the performance of coronary angioplasty.4 I These advantages now appear to extend to coronary angioplasty of functionally occluded vessels, and this report describes our experience in 13 such patients, with attention to the unique technical and coronary hemodynamic considerations present in this patient population.
MethodsOf 47 consecutive patients (ages 35 to 81 years) who underwent coronary angioplasty at the Beth Israel Hospital between December 1981 and February 1983, 13 patients (group A) did so despite total occlusion (100%) or functional total occlusion (99%) of the involved vessel. Total vessel occlusion (figure 1) was defined as absent antegrade filling beyond the lesion. Functional total occlusion (figure 2) was defined as faint, late antegrade opacification of the distal segment in the absence of a discernible luminal continuity on detailed review of the cineangiogram. The remaining 34 patients (group B) had conventional stenoses between 75% and 95% (mean 91 + 5%) with evident luminal continuity.
CIRCULATION