“…Although CT-or MR-imaging and echocardiography provide accurate assessment of the size, location and point of attachment of these tumors, tissue characterization is not possible [2,3]. Therefore, a variety of transluminal techniques such as forceps biopsy [4,5], brushing [6], aspiration [7,8] or scoop biopsy [9] have been utilized to obtain tissue for histological or cytological examination of cavo-atrial tumors. However, there are several known causes of erroneous or non-diagnostic samplings associated with some of these techniques including superficial apposition clots, low cellularity of the lesion or crushing artefacts.…”