Percutaneous secundum atrial septal defect closure for the treatment of atrial arrhythmia in the adult: A meta-analysis

O’Neill, Louisa; Floyd, Christopher N.; Sim, Iain; Whitaker, John; Mukherjee, Rahul; O’Hare, Daniel; Frigiola, Alessandra; O’Neill, Mark; Williams, Steven E.

doi:10.1016/j.ijcard.2020.07.014

Cited by 6 publications

(3 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It has been reported that the incidence of arrhythmia can be up to 5-10% during the procedure and during follow-up. [19][20][21][22][23] In our study, atrial fibrillation was observed in two (1.4%) patients and was found to be similar to the literature.…”

Section: Discussionsupporting

confidence: 90%

Procedural and Short-Term Results of Percutaneous Atrial Septal Defect Closure in Adolescents and Adults

Can,

Kocayigit,

Aksoy

et al. 2022

Pak Heart J

View full text Add to dashboard Cite

Objectives: To evaluate the procedural and short-term results of percutaneous atrial septal defect (ASD) closure in adults. Methodology: We retrospectively analysed 149 consecutive patients with a secundum ASD who underwent percutaneous closure from September 2011 to January 2021. Procedural and short-term results, including arrhythmia, device embolisation and residual shunt, were assessed at 2 days and 4 weeks and 6 months after percutaneous closure of atrial septal defect. Results: The patients were 14 to 77 (37.7 ± 15.0) years old and 101 (67.8%) were female. Maximum defect size was 18.0 ± 6.3 mm measured on transoesophageal echocardiography. The device diameter used in patients who underwent closure was 21.9 ± 6.9 mm (6–38 mm). Percutaneous closure procedure success rate was 93.3%. In our study, the rates of device embolisation, arrhythmia and residual shunt were 3.6%, 1.4%, and 2.2%, respectively. Conclusion: Transcatheter closure of ASDs in adults was feasible in our centre with good short-term outcome. The procedure should be performed in experienced centres by cardiologists specialised in the treatment of structural heart diseases due to potentially severe complications.

show abstract

Section: Discussionsupporting

confidence: 90%

Procedural and Short-Term Results of Percutaneous Atrial Septal Defect Closure in Adolescents and Adults

Can,

Kocayigit,

Aksoy

et al. 2022

Pak Heart J

View full text Add to dashboard Cite

show abstract

“…A meta-analysis of 25 studies demonstrated that transcatheter ASD closure is not associated with a reduction in the prevalence of any atrial arrhythmias. It showed a small benefit in patients ≥ 40 years but not those ≥ 60 years [ 21 ]. These findings suggest that the mechanisms underlying atrial arrhythmias in these patients are not fully understood and go beyond the ASD itself.…”

Section: Predictors Of Arrhythmias After Asd Interventional Closurementioning

confidence: 99%

“…Age ≥ 40 yrs [20][21][22] Male gender [23] Metabolic syndrome [24] Thyroid dysfunction [24] Atrial arrhythmia before closure [23,24] Atrial arrhythmia ≤ 1 month after closure [23] BNP levels ≥ 40 pg/mL [19] Echocardiography parameters Larger ASD defect [24,25] Multiple ASDs [24] LA and RA dysfunction/remodeling [9,26,27] Mitral valve disease [24] SPAP ≥ 25 mmHg [15,23] Impaired systolic myocardial velocity of RV [15] Electrocardiography parameters Increased P-wave duration/dispersion [9,15,28,29] Crochetage sign [30] QT interval, QTc duration and dispersion [29,31] Tp-e interval, Tp-e/QT ratio [31] Parameters related to the procedure or the device Larger device size [17,24] Fenestrated occluder [24] ASO/ASL ratio > 0.576 [32] Longer fluoroscopy time [17] ASD-atrial septal defect; BNP-brain natriuretic peptide; LA-left atrium; RA-right atrium; SPAP-systolic pulmonary arterial pressure; RV-right ventricle; Tp-e-T wave to peak-end interval;; QTc -corrected QT interval; ASO-atrial septal occluder; ASL-atrial septal length.…”

Section: Clinical and Demographic Parametersmentioning

confidence: 99%

Arrhythmic Risk and Treatment after Transcatheter Atrial Septal Defect Closure

Deaconu,

Marascu

et al. 2023

Diagnostics

View full text Add to dashboard Cite

Atrial septal defect (ASD) represents the most common congenital heart defect identified in adulthood. Atrial and ventricular geometric remodeling due to intracardiac shunt increase the risk of arrhythmias, especially atrial fibrillation (AF). Clinical, echocardiography, electrocardiogram, and device-related predictors may be used to assess the risk of atrial arrhythmias after ASD closure. The underlying mechanisms in these patients are complex and at least in part independent of the structural remodeling secondary to hemodynamic overload. Device closure of the ASD itself and its timing impact future arrhythmia risk, as well as posing a challenge for when transseptal puncture is required. Sudden cardiac death (SCD) risk is higher than in the general population and an implantable cardioverter-defibrillator (ICD) may be indicated in selected cases.

show abstract

Atrial septal defects

Bergersen

2025

Nadas' Pediatric Cardiology

View full text Add to dashboard Cite

Percutaneous secundum atrial septal defect closure for the treatment of atrial arrhythmia in the adult: A meta-analysis

Cited by 6 publications

References 40 publications

Procedural and Short-Term Results of Percutaneous Atrial Septal Defect Closure in Adolescents and Adults

Procedural and Short-Term Results of Percutaneous Atrial Septal Defect Closure in Adolescents and Adults

Arrhythmic Risk and Treatment after Transcatheter Atrial Septal Defect Closure

Atrial septal defects

Contact Info

Product

Resources

About