Percutaneous radiological gastrostomy: a safe and effective method of nutritional tube placement in advanced ALS

Chiò, Adriano; Galletti, R; Finocchiaro, Concetta; Righi, Dorico; Ruffino, Maria Antonella; Calvo, Andrea; Vito, N. Di; Ghiglione, Paolo; Terreni, Anna; Mutani, Roberto

doi:10.1136/jnnp.2003.020347

Cited by 135 publications

(76 citation statements)

References 15 publications

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“…The PRG technique appears to be a safe and effective alternative to PEG in ALS patients (16). The procedural morbidity and mortality results between conventional and radiological methods of gastrostomy insertion are not significantly different (17).…”

Section: Discussionmentioning

confidence: 98%

Comparison of two percutaneous radiological gastrostomy tubes in the nutritional management of ALS patients

Rio¹,

Ampong

Turner

et al. 2005

Amyotrophic Lateral Sclerosis

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Patient care and minimizing complications post gastrostomy have to date received little attention in ALS patients. We compare the complications associated with pigtail and mushroom type percutaneous radiological gastrostomy tubes in this patient group. Patients requiring PRG received either Wills-Oglesby or the skin level Entristar. Retrospective review of the clinical notes was performed capturing demographic data, peristomal infection, tube displacement, tube failure, nutritional status, site of disease onset, and survival. Thirty-five patients (Group 1) had the Wills-Oglesby tube of which 14 (40%) tubes required replacement. The Entristar tube was inserted in 29 patients (Group 2) where 8 (28%) required replacement (NS). The incidence of infection was significantly lower with the Entristar tube, (p<0.001). The mean time to tube removal in Group 2 was 223 days (SD 147; range 71-494 days) due to 'buried bumper syndrome'. We conclude that the Entristar skin level gastrostomy tube is associated with a reduction in peristomal infection, tube failure and blockage compared with the Wills-Oglesby tube.

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Section: Discussionmentioning

confidence: 98%

Comparison of two percutaneous radiological gastrostomy tubes in the nutritional management of ALS patients

Rio¹,

Ampong

Turner

et al. 2005

Amyotrophic Lateral Sclerosis

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“…In contrast to the reported data on nutritional interventions, there is a more consistent benefit demonstrated on survival and quality of life [115,124,125]. The timing of this respiratory intervention may introduce another source of variability on survival, quality of life, and overall function.…”

Section: Respiratory Therapiesmentioning

confidence: 93%

Challenges in the Understanding and Treatment of Amyotrophic Lateral Sclerosis/Motor Neuron Disease

Rosenfeld¹,

Strong

2015

Neurotherapeutics

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With the acceleration in our understanding of ALS and the related motor neuron disease has come even greater challenges in reconciling all of the proposed pathogenic mechanisms and how this will translate into impactful treatments. Fundamental issues such as diagnostic definition(s) of the disease spectrum, relevant biomarkers, the impact of multiple novel genetic mutations and the significant effect of symptomatic treatments on disease progression are all areas of active investigation. In this review, we will focus on these key issues and highlight the challenges that confront both clinicians and basic science researchers.

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“…The cut-off limit for a safe PEG placement has been considered a FVC% ≥ 50 of expected values in dysphagic patients [7] and this has led to the suggestion of percutaneous radiological gastrostomy (PRG) as an alternative procedure to PEG [11,12]. While this latter approach is safe, it however requires the presence of an expert interventional radiologist [12].…”

Section: Introductionmentioning

confidence: 98%

Percutaneous endoscopic gastrostomy in amyotrophic lateral sclerosis: Effect on survival

Spataro

Ficano

Piccoli

et al. 2011

Journal of the Neurological Sciences

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Percutaneous radiological gastrostomy: a safe and effective method of nutritional tube placement in advanced ALS

Cited by 135 publications

References 15 publications

Comparison of two percutaneous radiological gastrostomy tubes in the nutritional management of ALS patients

Comparison of two percutaneous radiological gastrostomy tubes in the nutritional management of ALS patients

Challenges in the Understanding and Treatment of Amyotrophic Lateral Sclerosis/Motor Neuron Disease

Percutaneous endoscopic gastrostomy in amyotrophic lateral sclerosis: Effect on survival

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