Percutaneous radiofrequency ablation (RFA) for hepatocellular carcinoma.

往夫, 大崎; 達, 木村; 竜一, 喜多; 裕之, 国立; 正剛, 高松; 達夫, 清水

doi:10.2957/kanzo.42.22

Cited by 8 publications

(3 citation statements)

References 11 publications

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“…One of the main advantages of using laparoscopic ablation is its low local recurrence rate. The local recurrence rate after well‐defined percutaneous RFA protocols reportedly ranges from 5.4% to 15% 18,19 . A significant underlining cause for the local recurrence is the tumor size, 20 and this suggests that the improved ablation technique may lower the local recurrence rate.…”

Section: Discussionmentioning

confidence: 99%

Laparoscopic ablation therapy for hepatocellular carcinoma. Clinical significance of a newly developed laparoscopic sector ultrasonic probe

Noguchi

Izumi

Inoue

et al. 2003

Digestive Endoscopy

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Background: Although a laparoscopic approach for local ablation plays an important role in treating hepatocellular carcinoma (HCC) near the liver surface, precise targeting ablation has been difficult using a conventional linear ultrasonic probe. We have recently developed a sector ultrasonic probe with a guiding tract for precisely targeting tumors. Methods: Since 1996, 349 HCC cases have been treated with either microwave or radiofrequency ablation. A percutaneous approach was selected in 298 cases, and a laparoscopic approach was selected in 51 cases. The laparoscopic approach was selected in the cases in which serious complications due to the tumors being located on the surface or protruding from the liver, or adjacent to the gallbladder or intestine made it difficult to treat percutaneously. In the latest 21 cases, the sector ultrasonic probe was used. Results: All the cases were safely and successfully treated by laparoscopic ablation with an exception by an extensive HCC case with portal vein tumor thrombus. Survival after the treatment by laparoscopic ablation was 95.2% in 1 year, and 82.4% in 3 years. The tumor stage was a significant prognostic factor (P < 0.0001). There was no local recurrence within 6 months of treatment in the successfully treated cases. The use of the sector probe widened indications for the laparoscopic approach for treating HCC. Conclusion: Laparoscopic ablation can result in a satisfactory outcome in difficult‐to‐treat cases by the percutaneous approach. The newly developed sector ultrasonic probe has allowed us more therapeutic choices in the treatment of HCC.

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Section: Discussionmentioning

confidence: 99%

Laparoscopic ablation therapy for hepatocellular carcinoma. Clinical significance of a newly developed laparoscopic sector ultrasonic probe

Noguchi

Izumi

Inoue

et al. 2003

Digestive Endoscopy

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“…The most common adverse effects of RFA are pain, fever, and an elevation of transaminase levels12, 13,15). These effects are generally transient and do not require any specific therapy.…”

Section: Complicationsmentioning

confidence: 99%

“…However, several major complications requiring specialized therapy have been reported, and the incidence of major complications is 5-10% of all patients10- 13,15,16,18,28,37,38). These complications include pleural effusion, ascites, intraperitoneal bleeding, hemorrhage in the treated tumor, pleurisy, hydropneumothorax, ventricular fibrillation, bleeding from the subcostal wound, jaundice, gastric ulcer, and needle tract seeding.…”

Section: Complicationsmentioning

confidence: 99%

Radiofrequency Ablation for Primary and Metastatic Liver Tumors: Indications and Therapeutic Effects.

et al. 2002

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Radiofrequency ablation therapy (RFA) is considered to be a reliable alternative to surgical resection for patients with primary and metastatic liver tumors. RFA delivers energy into the tumor through non-insulated needle electrode tips, causing a high-frequency alternating current to flow and resulting in coagulation necrosis of the tumor tissue. Compared to percutaneous ethanol injection (PEI) and microwave coagulation therapy (MCT), RFA can induce a larger and more predictable area of coagulation necrosis. Therefore, this technique may reduce the number of required treatment sessions and shorten the hospital stay. Three different RFA devices are presently available, and their usefulness has been compared. Representative adverse effects of RFA include local pain, intra-abdominal bleeding, pleural complications, and needle tract seeding. Although more studies are required to precisely define the indications and to estimate the long-term effects, RFA is expected to become a major therapeutic technique for the treatment of primary and metastatic liver tumors.

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Forefront of radiofrequency ablation treatment of hepatic cancer. 7. Side effect and complication of radiofrequency ablation.

博志¹

2005

Kanzo

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Percutaneous radiofrequency ablation (RFA) for hepatocellular carcinoma.

Cited by 8 publications

References 11 publications

Laparoscopic ablation therapy for hepatocellular carcinoma. Clinical significance of a newly developed laparoscopic sector ultrasonic probe

Laparoscopic ablation therapy for hepatocellular carcinoma. Clinical significance of a newly developed laparoscopic sector ultrasonic probe

Radiofrequency Ablation for Primary and Metastatic Liver Tumors: Indications and Therapeutic Effects.

Forefront of radiofrequency ablation treatment of hepatic cancer. 7. Side effect and complication of radiofrequency ablation.

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