Percutaneous radiofrequency ablation of renal tumors: technique, limitations, and morbidity

Ogan, Kenneth; Jacomides, Lucas; Dolmatch, Bart L.; Rivera, Frank J.; Dellaria, Marco F; Josephs, Shellie C.; Cadeddu, Jeffrey A.

doi:10.1016/s0090-4295(02)02096-4

Cited by 145 publications

(55 citation statements)

References 12 publications

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“…As advocated by Ogan et al ( 41 ), it is recommended that the tines of the ablative probe be deployed to ablate 0.5-1.0 cm beyond the deepest margin of the tumor to achieve effective ablation and avoid the presence of viable tumor cells at the periphery of treated tumors. The anatomic location of the kidney also warrants close inspection for proximity between the renal tumor and nearby vulnerable structures such as the ureters, genitofemoral or ilioinguinal nerves, the psoas major muscle, small and large bowel, and the adrenal gland.…”

Section: Anatomic Considerations and Related Adjunctive Techniquesmentioning

confidence: 99%

Percutaneous Ablation in the Kidney

Venkatesan¹,

Wood²,

Gervais³

2011

Radiology

108

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1Percutaneous ablation in the kidney is now performed as a standard therapeutic nephron-sparing option in patients who are poor candidates for resection. Its increasing use has been largely prompted by the rising incidental detection of renal cell carcinomas with cross-sectional imaging and the need to preserve renal function in patients with comorbid conditions, multiple renal cell carcinomas, and/or heritable renal cancer syndromes. Clinical studies to date indicate that radiofrequency ablation and cryoablation are effective therapies with acceptable short-to intermediateterm outcomes and with a low risk in the appropriate setting, with attention to pre-, peri-, and postprocedural detail. The results following percutaneous radiofrequency ablation and cryoablation in the treatment of renal cell carcinoma are reviewed in this article, including those of several larger scale studies of ablation of T1a tumors. Clinical and technical considerations unique to ablation in the kidney are presented, and potential complications are discussed.q RSNA, 2011

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Section: Anatomic Considerations and Related Adjunctive Techniquesmentioning

confidence: 99%

Percutaneous Ablation in the Kidney

Venkatesan¹,

Wood²,

Gervais³

2011

Radiology

108

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“…In general, RCC tumors that are Յ3 cm in diameter are ideal for ablation, with near-perfect success rates on postprocedural imaging (7-13). Most tumors smaller than 3 cm can also be treated successfully in a single session (7)(8)(9)(10)(11)(12)(13). Tumors between 3.0 and 3.5 cm in diameter can also be treated successfully with confidence, but multiple ablations and sessions may be required (7)(8)(9)(10)(11)(12)(13).…”

Section: Tumor Factorsmentioning

confidence: 99%

“…Even larger exophytic tumors are almost always treated successfully, with Ն70% requiring only a single RF session (7)(8)(9)(10)(11)(12)(13). Parenchymal tumors may be more difficult to treat, but centrally located tumors represent the largest obstacle for successful ablation.…”

Section: Tumor Factorsmentioning

confidence: 99%

“…Indeed, more than 5,000 RF ablations of focal liver tumors have been performed during the last 5 years, with Food and Drug Administration (FDA) approval being granted for this indication (1)(2)(3)(4)(5)(6). More recently, however, the clinical potential of RF ablation has greatly expanded under the blanket FDA approval for soft tissue including the treatment of kidney (7)(8)(9)(10)(11)(12)(13), breast (14), bone (15)(16)(17), lung (18), retroperitoneum (19), thyroid (20), adrenal gland (21), spleen (22), prostate (23,24), and even pheochromocytoma (25). One site in particular, the kidney, is poised for significant growth as a target for RF ablation.…”

Section: Introductionmentioning

confidence: 99%

“…One site in particular, the kidney, is poised for significant growth as a target for RF ablation. A contributing factor includes the significant increase in the incidence of renal cell carcinoma (RCC), which, when coupled with improved understanding of RF techniques, has recently led many investigators to assess the feasibility and efficacy of RF ablation for renal tumors in select patient populations (7)(8)(9)(10)(11)(12)(13).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Review of Radiofrequency Ablation for Renal Cell Carcinoma

Hines-Peralta

Goldberg

2004

Clinical Cancer Research

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This review will discuss how minimally invasive, imageguided radiofrequency (RF) tumor ablation [i.e., coagulating tumor using short-duration heating (<15 minutes) by directly applying temperatures >50°C via needle electrodes] is being incorporated as a clinical tool for the treatment of renal cell carcinoma. RF ablation has been used to treat focal liver tumors. Potential benefits of this thermal therapy include reduced morbidity and mortality compared with standard surgical resection and the ability to treat nonsurgical patients. More recently, this technique has been introduced to treat focal renal tumors, particularly incidental lesions smaller than 3 cm in elderly patients and those with comorbid conditions. Other uses have included treatment in patients with von Hippel-Lindau syndrome and other diseases that predispose patients to multiple renal carcinomas, where renal parenchymal preservation is desired. Techniques, complications, and results will be discussed. Additionally, strategies that we are currently studying to improve RF outcomes and enable the potential treatment of larger tumors will be addressed. Most notably, recent data on increased coagulation achieved by combining RF ablation with antivascular/antiangiogenic therapies, such as arsenic trioxide, that reduce blood flow and promote heat retention are provided.

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Radiofrequency Ablation of Renal Tumors

Steinberg

Tracy

2018

Smith's Textbook of Endourology

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Percutaneous radiofrequency ablation of renal tumors: technique, limitations, and morbidity

Cited by 145 publications

References 12 publications

Percutaneous Ablation in the Kidney

Percutaneous Ablation in the Kidney

Review of Radiofrequency Ablation for Renal Cell Carcinoma

Radiofrequency Ablation of Renal Tumors

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