Percutaneous kyphoplasty treatment evaluation for patients with K�mmell disease based on a two‑year follow‑up

Abstract

Percutaneous kyphoplasty (PKP) has been used in Kümmell disease treatment for years. The objective of the current study was to evaluate the efficacy and safety of PKP in the treatment of patients with Kümmell disease and to explore the association between cement injection volume and pain relief. A total of 50 patients were enrolled in the present study and follow-up was 2 years. Efficacy was evaluated using the Visual Analog Scale (VAS), the Oswestry Disability Index (ODI) and the kyphotic angle (Cobb's angle). VAS and ODI were determined at the initial evaluation (prior to surgery), at 3 days, 3 months, and 1 and 2 years post surgery. Cobb's angle was measured prior to and 3 months, 1 year and 2 years following surgery. PKP safety was assessed by evaluating complications, including cement leakage and spinal cord compression. In the follow-ups, VAS significantly decreased from 7.00±0.78 pre-PKP to 3.14±0.67 at 2 years post-PKP (P<0.05). ODI significantly decreased from 73.88±8.60 prior to surgery to 22.84±8.85 at 1 year following surgery (P<0.05) and did not significantly change at the following 2-year measurement (26.44±8.63). The Cobb's angle, measured at 17.73±2.43° preoperatively, significantly decreased to 8.32±2.21° at 3 months following surgery (P<0.05). On subsequent follow-ups at 1 and 2 years, the Cobb's angle increased to 9.55±2.82 and 10.27±3.22°, respectively. A total of 8 patients exhibited signs of cement leakage during the PKP procedure. No patients experienced severe neurological deficits or complications. Spearman analysis demonstrated a positive correlation between cement injection volume and pain relief. The current study indicated that PKP was a safe and effective treatment for patients with Kümmell disease and that there was a positive correlation between cement injection volume and pain relief. The current study may be used a reference in cement dosing for the treatment of PKP.

Comparison of the clinical outcomes of percutaneous vertebroplasty vs. kyphoplasty for the treatment of osteoporotic Kümmell’s disease:a prospective cohort study

“…After filling the fissures in the vertebral body with bone cement, the height and kyphosis deformity of the vertebral body were partially restored and corrected, and the abnormal activity of the injuried vertebral body was eliminated, which was an important reason for pain relief [11]. Previous studies have found that both PVP and PKP can effectively relieve the lower back pain of Kümmell's disease, achieve satisfactory clinical effect, and at the same time partially restore the height of the vertebra and correct the kyphosis [11,[21][22][23][24][25][26][27][28]. During spinal flexion and extension, due to the presence of IVC and the formation of false joints, the injured vertebra of Kümmell's disease can stretch and expand, which can widen the fractured vertebra.…”

Comparison of the clinical outcomes of percutaneous vertebroplasty vs. kyphoplasty for the treatment of osteoporotic Kümmell’s disease:a prospective cohort study

“…After filling the fissures in the vertebral body with bone cement, the height and kyphosis deformity of the vertebral body were partially restored and corrected, and the abnormal activity of the injuried vertebral body was eliminated, which was an important reason for pain relief [11]. Previous studies have found that both PVP and PKP can effectively relieve the lower back pain of Kümmell's disease, achieve satisfactory clinical effect, and partially restore the height of the vertebra and correct the kyphosis [11,[22][23][24][25][26][27][28][29]. During spinal flexion and extension, due to the presence of IVC and the formation of pseudojoint, the injured vertebra of Kümmell's disease can stretch and expand, which can widen the fractured vertebral body.…”

WITHDRAWN: Are Intravertebral Clefts Kümmell’s Disease?

“…The inclusion criteria were following: (1) aged 60 years or older; (2) fragility fracture of thoracic or lumbar vertebra (without trauma or with minor trauma, as tumble or sprain); (3) underwent surgical intervention; (4) IVC in the vertebral body could be found by CT imaging; (5) complete radiological information including X-ray, CT, and MRI could be achieved. Exclusion criteria were following: (1) burst fracture of a thoracic and lumbar vertebra; (2) pathological fracture due to infection or malignancy; (3) with adjacent vertebral fractures; (4) incomplete radiological information; (5) younger than 60 years old; (6) cannot recall the details about the injury; (7) with no history of injury; (8) underwent conservative treatment. The study was approved by the institutional review board and the ethics committee of our hospital.…”