Percutaneous kyphoplasty in the treatment of painful osteoblastic metastatic spinal lesions

Chen, Guangdong; Luo, Zong‐Ping; Zhang, Hongtao; Nalajala, Badri; Yang, Huilin

doi:10.1016/j.jocn.2012.08.010

Cited by 15 publications

(12 citation statements)

References 13 publications

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“…The use of polymethylmethacrylate (PMMA) cement to fill painful and lytic lesions in bone has been well studied in the spinal literature and has an established history of reducing the pain attributable to bone lesions in these patients. [11][12][13][14] Use of PMMA outside of the spine was reported by Cotton et al 16 in 1995 and subsequently has been shown to reduce pain from metastases throughout the axial and appendicular skeleton. 15 The current results corroborate these findings, with the majority of patients experiencing significant pain reduction and only 1 patient requiring eventual reconstruction.…”

Section: Discussionmentioning

confidence: 99%

“…Although excision and reconstruction may be an option for some patients, many undergo vertebroplasty and balloon kyphoplasty of the affected area for pain relief. Several studies in the literature have reported pain reduction and return to function using such techniques, [11][12][13][14] and a few authors have published results using similar cementoplasty techniques in extraspinal osseous sites for relief of pain from metastasis. 15,16 The current authors have used percutaneous cement augmentation (acetabuloplasty) as a minimally invasive alternative to acetabular reconstruction for patients who have metastatic involvement of the periacetabular area, without fracture or loss of the integrity of the acetabular surface.…”

Section: Introductionmentioning

confidence: 99%

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Percutaneous Acetabuloplasty for Metastatic Lesions to the Pelvis

Durfee¹,

Sabo²,

Letson³

et al. 2017

Orthopedics

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Metastatic lesions of the acetabulum can be painful and debilitating. First-line treatment is multimodal and consists of disease-specific chemotherapy, osteoclastic inhibitors, analgesics, and radiation therapy. When these therapies fail, surgical intervention usually is indicated and varies from regional defect stabilization to large periacetabular reconstructions that are demanding procedures with high rates of complications. Percutaneous cement augmentation (acetabuloplasty) of lesions in selected patients has been explored as a less invasive method of lesional control. This retrospective review included 11 patients with painful periacetabular lesions who underwent percutaneous acetabuloplasty using fluoroscopic guidance from 2007 to 2012, in addition to standard treatment with either radiation or chemotherapy, or a combination of both radiation and chemotherapy. Primary tumors included 4 multiple myeloma, 4 renal cell, and 3 breast malignancies. Mean procedure length was 58.4 minutes, and mean hospital stay was 1.4 days (range, 1-2 days). Mean blood loss was 33.4 mL, and there were no complications due to infection or cementation. Mean follow-up was 26.4 months (range, 3-36 months), with 2 patients dying from complications of underlying disease. All of the patients experienced pain relief following the procedure, with mean visual analog scale scores improving from 7.7 to 2.1 (P=.002). Postoperative Musculoskeletal Tumor Society and Oxford hip scores were obtained for 7 of 11 patients and demonstrated improvement. One patient underwent conversion to an acetabular reconstruction due to disease progression. This report demonstrates the effective use of a minimally invasive procedure to provide acute stability, pain relief, and good functional outcomes in patients with periacetabular metastatic lesions without pathologic fracture. [Orthopedics. 2017; 40(1):e170-e175.].

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Percutaneous Acetabuloplasty for Metastatic Lesions to the Pelvis

Durfee¹,

Sabo²,

Letson³

et al. 2017

Orthopedics

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“…One of the major problems of the percutaneous techniques is the possible extravasations of cement outside the bone region where it aims to be located. One solution to this undesirable event is the decompression of the vertebra by re-intervention by surgery (CHEN;LUO;ZHANG;NALAJALA et al, 2013;GERSZTEN, 2007;HENDRICKSON;SHEHATA;KIRCHNER, 1976). These percutaneous procedures are complementary to therapeutic treatments within tumor control (KANEKO; SEHGAL; SKINNER; AL-GHAZI et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Estudo E Implementação De Microcontroladores Na Automação De Shopping Center

Santos¹,

Neves²,

Rosa³

et al. 2021

Projeto, Análise E Otimização Na Área Das Engenharias

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“…The quality of life of patients is significantly reduced 6 . Analgesics, radiotherapy, chemotherapy, and other conservative drugs are sometimes ineffective or short-lived 7 .…”

Section: Introductionmentioning

confidence: 99%

Minimally Invasive Pedicle Screw Fixation Combined with Percutaneous Kyphoplasty Under O‐Arm Navigation for the Treatment of Metastatic Spinal Tumors with Posterior Wall Destruction

Zhou

Wang

Xiao

et al. 2020

Orthopaedic Surgery

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Objective To evaluate the safety and efficacy of O‐arm‐guided minimally invasive pedicle screw fixation combined with percutaneous kyphoplasty for metastatic spinal tumors with posterior wall destruction. Methods Patients who underwent minimally invasive pedicle screw fixation combined with percutaneous kyphoplasty for pathological vertebral fractures with posterior wall defects from January 2015 to December 2017 were followed up for 1 year. Visual analogue scale (VAS), SF‐36 scores, middle vertebral height, posterior vertebral height, and the accuracy of pedicle screws were assessed preoperatively, postoperatively, and 1 year after surgery. The operation time, time from operation to discharge, blood loss, volume of bone cement, and leakage of bone cement were recorded. Results Twenty‐three patients (13 females and 10 males) who met our criteria were followed up for 1 year. The operation time of these patients was 162.61 ± 33.47 min, the amount of bleeding was 230.87 ± 93.76 mL, the time from operation to discharge was 4.35 ± 2.42 days, and the volume of bone cement was 3.67 ± 0.63 mL. The VAS score decreased from 7.04 ± 1.07 to 2.65 ± 0.93 before surgery (P = 0.000) and remained at 2.57 ± 0.79 1 year after surgery. Compared with the preoperative SF‐36 scores for physical pain, physiological function, energy, and social function, the postoperative scores were significantly improved (P = 0.000). The height of the middle vertebral body increased from 14.47 ± 2.96 mm before surgery to 20.18 ± 2.94 mm (P = 0.000), and remained at 20.44 to 3.01 mm 1 year after surgery. The height of the posterior vertebral body increased from 16.56 ± 3.07 mm before operation to 22.79 ± 4.00 mm (P = 0.000), and 22.45 ± 3.88 mm 1 year after surgery. The 23 patients had a total of 92 pedicle screws; 85 screws were Grade A and 7 screws were Grade B. There was no leakage of bone cement after surgery. Conclusion In the short term, O‐arm‐guided minimally invasive pedicle screw fixation combined with kyphoplasty is safe and effective in the treatment of metastatic spinal tumors with posterior wall destruction.

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Percutaneous kyphoplasty in the treatment of painful osteoblastic metastatic spinal lesions

Cited by 15 publications

References 13 publications

Percutaneous Acetabuloplasty for Metastatic Lesions to the Pelvis

Percutaneous Acetabuloplasty for Metastatic Lesions to the Pelvis

Estudo E Implementação De Microcontroladores Na Automação De Shopping Center

Minimally Invasive Pedicle Screw Fixation Combined with Percutaneous Kyphoplasty Under O‐Arm Navigation for the Treatment of Metastatic Spinal Tumors with Posterior Wall Destruction

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