Percutaneous injection sclerotherapy with minocycline hydrochloride for simple renal cysts

Ohkawa, Mitsuo; Tokunaga, Shuji; Orito, Matsuo; Shimamura, Masayoshi; Hirano, Shoji; Okasho, Akira; Kosaka, Shinji

doi:10.1007/bf02552252

Cited by 54 publications

(35 citation statements)

References 21 publications

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“…The mean length of final radiological follow up was 10.6 ± 3.4 months (range, [3][4][5][6][7][8][9][10][11][12]. A total of 12 cases were available at 12th month radiological follow up.…”

Section: Resultsmentioning

confidence: 99%

“…10 A more minimally invasive treatment alternative, percutaneous needle aspiration, is also in the treatment armamentarium of simple renal cysts, but recurrence can be observed in up to 55% of cases. 11,12 Therefore, needle aspiration is generally reserved in high risk patients, while laparoscopic surgery, with an overall success rate of 90%, is offered to the majority of cases at our institution.…”

Section: Discussionmentioning

confidence: 99%

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Retroperitoneal laparoscopic decortication of simple renal cysts using the bipolar PlasmaKinetic scissors

et al. 2006

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Objectives: To analyse the efficacy, safety and feasibility of retroperitoneal laparoscopic decortication of simple renal cysts using bipolar PlasmaKinetic scissors. Methods: Records of 19 patients who underwent laparoscopic decortication of simple renal cysts, performed with bipolar PlasmaKinetic scissors without additional fulguration of the base or the margin of resection, were retrospectively reviewed. Longterm symptomatic and radiological outcomes were assessed. Results: One single cyst was treated in fourteen (73.7%) cases, two cysts in three (15.8%) cases, three cysts in one (5.2%) case and multiple cysts in one case with autosomal dominant polycystic kidney disease. They were peripherally located in thirteen, peripelvic in three, and parenchymal in two cases. An average of 3.1 trochars were used for each procedure. The mean operating time was 82.5 ± 16.7 min (range, 50-135). Neither open conversion nor blood transfusion was necessary. A total of six minor complications were encountered. Mean hospital stay 2.3 ± 0.9 days (range, 1-4). After a mean follow up of 14.3 ± 5.9 months (range, 3-24), symptomatic success was achieved in 89.5%, and radiological success was accomplished in 88.2%. An asymptomatic cyst recurrence was observed in one (5.9%) case, and one (5.9%) case with residual pain had new cyst formation at another site of the kidney. Conclusions: Retroperitoneal laparoscopic cyst decortication using bipolar PlasmaKinetic scissors is a feasible and efficient method, eliminating further fulguration of the base and the margins of the cysts. Operating times are shorter than previously published series and highly satisfactory long-term success rates are achieved.

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“…The mean length of final radiological follow up was 10.6 ± 3.4 months (range, [3][4][5][6][7][8][9][10][11][12]. A total of 12 cases were available at 12th month radiological follow up.…”

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Retroperitoneal laparoscopic decortication of simple renal cysts using the bipolar PlasmaKinetic scissors

et al. 2006

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“…A low concentration of MINO (1 to 2 mg/mL) is usually injected intravenously. MINO injection has been used to treat renal cysts [66][67][68] , splenic cysts [69] , thyroid cysts [70] , and hepatic cysts [26,27,38,[41][42][43] . MINO 100 mg/mL was injected to treat thyroid cysts [70] , and MINO 10 mg/ mL [66] was instilled into renal cysts.…”

Section: Discussionmentioning

confidence: 99%

Repeated Minocycline Hydrochloride Injections for Symptomatic Polycystic Liver Disease

Yoshida

Makino

Yokoyama

et al. 2016

Journal of Gastroenterology and Hepatology Research

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AIM:The present study evaluated the safety and effectiveness of repeated injections of minocycline hydrochloride (MINO) for symptomatic polycystic liver disease (PLD). METHODS:We retrospectively studied patients who received percutaneous MINO injections for symptomatic PLD and were followed up for at least 2 years between 2002 and 2015. Huge hepatic cysts (diameter > 10 cm) were treated by continuous drainage and multiple MINO injections. Small hepatic cysts underwent one-step drainage followed by a single injection of MINO. Only several cysts that caused complications were treated by percutaneous injection of MINO. Patients were discharged 1 day after treatment. RESULTS: Ten patients, (4men and 6 women; mean age, 57.8 years) were studied. All patients had Type 2 PLD according to Gigot's classification. The chief complaints were abdominal distension (n = 10), abdominal pain (n = 6), back pain (n = 4), and appetite loss (n = 8). Four patients had mild liver dysfunction. One patient complained of moderate right subscapular pain immediately after the injection, and another had pain at the site of catheter insertion. Liver dysfunction did not develop in any patient after treatment. The mean follow-up was 63.4 months. The interval from the first to last admission for MINO injection therapy was 14 to 148 months (mean, 40.8 months). The number of admissions for MINO injection therapy ranged from 2 to 12 times (mean, 4.0 times). The average interval for MINO injection therapy was 8.3 to 19 months (mean, 14.8 months).The hepatic cysts shrank in all patients after treatment. Complications improved consistently, and all patients were satisfied with the outcome of treatment. CONCLUSIONS: Symptomatic PLD was controllable by 14.8 months of repeated MINO injections on average. Repeated MINO injections are a safe, definitive treatment for symptomatic PLD.

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“…Bu amaçla en sık olarak etanol kullanılmakta-dır [8]. Etanolün dışında asetik asit, glukoz, fenol, minosiklin hidroklorid ve povidon-iodin, etanolamin ve OK-432 gibi birçok sklerozan ajan, ayrıca tek veya çok seans skleroterapi, 12 veya 24 saatlik kateter aracılığıyla serbest drenajın eşlik ettiği skleroterapi, sklerozan ajanın değişik sürelerde kist içinde bırakılması gibi farklı teknikler kullanılmıştır [8][9][10][11][12][13]. Tek seans etanol ile skleroterapi yöntemiyle %90'ın üze-rinde başarı sağlamak mümkündür [8].…”

Section: Basit Böbrek Kistlerinde Perkütan Tedaviunclassified

Abdominal Abse, Sivi, Kist Drenajlari

Akıncı¹,

Çiftçi²

2015

Trd Sem

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Percutaneous injection sclerotherapy with minocycline hydrochloride for simple renal cysts

Cited by 54 publications

References 21 publications

Retroperitoneal laparoscopic decortication of simple renal cysts using the bipolar PlasmaKinetic scissors

Retroperitoneal laparoscopic decortication of simple renal cysts using the bipolar PlasmaKinetic scissors

Repeated Minocycline Hydrochloride Injections for Symptomatic Polycystic Liver Disease

Abdominal Abse, Sivi, Kist Drenajlari

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