Percutaneous Image-Guided Vertebral Fixation in Cancer-Related Vertebral Compression Fractures: A Case Series Study

Abstract

Background and objectives: Cancer-related vertebral compression fractures (VCF) may cause debilitating back pain and instability, affecting the quality of life of cancer patients. To further drive cement deposition during vertebroplasty, the aims of this restrospective case series study were to report the feasibility, safety and short term efficacy (≤6 months) of percutaneous vertebral fixation in cancer-related vertebral compression fractures using various intravertebral implants. Methods: All consecutive cancer patients treated with percutaneous vertebral fixation for VCF were retrospectively included. Various devices were inserted percutaneously under image guidance and filled by cement. Descriptive statistics were used and a matched paired analysis of pain scores was performed to assess for changes following interventions. Results: A total of 18 consecutive patients (12 women (66.6%) and 6 men (33.3%); mean age 59.7 ± 15.5 years) were included. A total of 42 devices were inserted in 8 thoracic and 16 lumbar vertebrae. Visual analogue scale measurement significantly improved from 5.6 ± 1.8 preoperatively to 1.5 ± 1.7 at 1 week (p < 0.01) and to 1.5 ± 1.3 at 6 months (p < 0.01). No severe adverse events were observed, but three adjacent fractures occurred between 1 week and 5 months after implantation. Conclusions: Percutaneous vertebral fixation of cancer-related VCF is feasible and safe and allows pain relief.

Interventional Oncology: 2024 Update

“…Interventional strategies for relieving pain, such as osteoplasty and fixation, are crucial components in managing cancer-related bone pain. 45,46 Osteoplasty involves injecting bone cement into areas of bone destruction or pathological fractures, 47 providing structural support and alleviating pain. Fixation techniques, which include percutaneous stabilization with screws or implants, [48][49][50] aim to reinforce weakened bone structures.…”

Innovative minimally invasive implants for osteoporosis vertebral compression fractures

“…The therapeutic efficacy of V-strut still requires further observation. However, this system is a highly promising, minimally invasive implant for OVCFs and cancer-related fracture treatment ( 56 ).…”