Percutaneous Image-Guided Spinal Lesion Biopsies: Factors Affecting Higher Diagnostic Yield

Yang, So Yeon; Oh, Eunsun; Kwon, Jong Won; Kim, Hyun Su

doi:10.2214/ajr.17.18817

Cited by 23 publications

(25 citation statements)

References 24 publications

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“…There are many studies in the literature about percutaneous vertebral biopsies performed with the help of imaging. In a recent study by Yang et al [4], including 247 spinal tumor biopsies, the diagnostic success rate was 80%. This rate was 77% in the study of Wu et al [8] and 77.14% in the study of Puri et al [9].…”

Section: Discussionmentioning

confidence: 96%

“…This rate was 77% in the study of Wu et al [8] and 77.14% in the study of Puri et al [9]. The factors affecting diagnostic success were listed as size, bone matrix and definitive diagnosis of lesion in the study of Yang et al [4]. In the study of Gul et al [10], the success rate was found to be 80% and the only factor that had a significant relationship with success was reported as lesion histopathology.…”

Section: Discussionmentioning

confidence: 97%

“…Percutaneous biopsy of bone lesions can be performed under the guidance of various imaging methods such as fluoroscopy, computed tomography (CT), ultrasonography (US) and magnetic resonance (MR). CT is the most widely used guide imaging method in spinal biopsies [4].…”

Section: Introductionmentioning

confidence: 99%

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Imaging-guided percutaneous vertebral and paravertebral lesion biopsy: A single center experience

Taydaş¹,

Ateş²,

Kindir³

2020

Journal of Surgery and Medicine

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This is an open access article distributed under the terms of the CreativeCommons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND 4.0) where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. AbstractAim: Percutaneous needle biopsy has been used successfully in the diagnosis of vertebral, paravertebral and disc diseases in recent years as it is a minimally invasive, safe, and effective method. The aim of this study was to share our experience with imaging-guided percutaneous vertebral and paravertebral biopsies. Methods: Images and data of 10 patients who underwent percutaneous vertebral and paravertebral biopsies between January 2018 and December 2019 were screened retrospectively through the hospital registry. The anatomical location of the lesion, guideline imaging method, number of samples taken, whether there were any complications after the procedure, needle diameter used, hemoglobin (Hb) values before and after the procedure were recorded. Results: Among 10 patients included in the study, 3 (30%) were male and 7 (70%) were female. The mean age of the patients was 63.5 (8.6) years. Biopsies were performed under computerized tomography and ultrasound guidance in nine patients and one patient, respectively. The lesion was located at the thoracic level in 4 patients (40%) and at the lumbar level in 6 patients (60%). Two samples were obtained from all patients. There were no complications. The mean Hemoglobin (Hb) values before and after the procedure were 10 (1.1) mg/dL and 10.2 (1.4) mg/dL, respectively, which were similar (P=0.91). 18G needle was used in all patients. Conclusion: Imaging-guided percutaneous vertebral and paravertebral biopsy is a safe and effective method which allows sampling for cytological, histological, and microbiological analysis. In the future, imaging techniques and biopsies will be increasingly used in the diagnosis of vertebral and paravertebral lesions.

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 97%

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Imaging-guided percutaneous vertebral and paravertebral lesion biopsy: A single center experience

Taydaş¹,

Ateş²,

Kindir³

2020

Journal of Surgery and Medicine

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“…However, they did not include cases of infectious spondylitis in their study. 23 In studies evaluating CT-guided biopsies specifically for vertebral osteomyelitis, the reported diagnostic yield has been much lower. For instance, Garg et al found histological examination provided positive results in 25 (41.0%) of the 61 samples collected for suspected cases of vertebral osteomyelitis; whereas the microbiology samples were even less predictive, with only 16 of the 84 samples collected (19.0%) yielding a positive result.…”

Section: Discussionmentioning

confidence: 99%

Computed Tomography-Guided Vertebral Biopsy in Suspected Tuberculous Spondylodiscitis: Comparing a New Navigational Tram-Track Technique versus Conventional Method

Singh

Sharma

Boruah

et al. 2020

Journal of Clinical Interventional Radiology ISVIR

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Introduction Computed tomography (CT)-guided vertebral biopsy is always recommended for histopathological and microbiological confirmation in cases of tuberculous spondylodiscitis and for antimycobacterial drug sensitivity testing. Aim To compare the conventional technique and a novel axis-defined tram-track technique of CT-guided vertebral biopsy in suspected tuberculous spondylodiscitis. Materials and Methods Sixty-seven patients of clinico-radiologically suspected tuberculous spondylodiscitis referred for CT-guided vertebral biopsy were categorized into two groups: “Group A” patients (n = 32) underwent biopsy by conventional technique, and “Group B” patients (n = 35) by axis-defined tram-track technique. The time taken for procedure, radiation exposure, and any procedural complications were recorded for both the groups. Results A statistically significant difference in procedure time and mean radiation dose was observed between the two groups: a longer procedural time was required in “Group A” (52.5 ± 3.5 minutes) as compared to “Group B” (37.3 ± 3.6 minutes) (p < 0.0001); and mean radiation dose (CTDIvol) in “Group A” and “Group B” was 8.64 ± 1.06 mGy and 5.73 ± 0.71 mGy, respectively (p < 0.0001). However, the difference in complication rate and tissue yield for successful diagnosis of the biopsies in the two groups was found to be statistically insignificant. Conclusion Axis-defined tram-track technique was found to have a significantly shorter procedural time as well as lower radiation exposure compared to the conventional technique of vertebral biopsy in our study.

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“…Advances in imaging have improved lesion detection and also facilitated better differentiation of benign and malignant lesions. 1 In particular, Magnetic Resonance (MR) imaging, with its multiplanar capabilities, and excellent soft tissue contrast resolution, plays a pivotal role in characterizing these lesions. 2 Though some of these lesions (e.g., hemangiomas) have characteristic imaging findings, a definitive diagnosis is not always possible, and biopsy is needed to confirm the diagnosis of such indeterminate lesions.…”

Section: Introductionmentioning

confidence: 99%

Comparative analysis of CT guided vertebral biopsy by a conventional bone biopsy needle versus bone biopsy needle with acquisition cradle

Singh

Boruah

Sharma

et al. 2021

Journal of Clinical Orthopaedics and Trauma

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Background: We aimed to compare the rate of diagnostically successful vertebral biopsies using conventional bone biopsy needles versus those performed with bone biopsy needles with an acquisition cradle. Methods: We retrospectively analyzed the data of patients who underwent CT-guided vertebral biopsy between December 2017 to December 2019 at our institute. From December 2017 to November 2018, the procedure was performed on 185 patients using an 11G conventional bone biopsy needle, Jamshidi needleTM "(group 1)". From December 2018 to December 2019, the procedure was performed on 242 patients using an 11G T-handle Jamshidi needle with an acquisition cradle "(group 2)". We reviewed their histopathological reports for both groups of patients to determine the rate of diagnostically successful biopsies. We also compared the crush artifact amongst the unsuccessful biopsy samples acquired by the two types of biopsy needles. Results: 427 patients (270 male and 157 female patients; mean age, 46.4 years; age range, 25e67 years) who underwent CT-guided vertebral biopsy from December 2017 to December 2019 were included in our study. In group 1, diagnostic success was achieved in 136 out of 185 biopsies (73.5%); whereas in group 2, diagnostic success was achieved in 219 out of 242 biopsies (90.50%), p < 0.0001. Out of the diagnostically unsuccessful biopsies in Group 1, 36 out of 49 (73.5%) were due to crush artifact; whereas crush artifact accounted for only 3 out of 23 (13.0%) diagnostically unsuccessful biopsies in group 2, p < 0.0001. Other causes of unsuccessful biopsies (hemorrhagic contents or presence of normal osseous tissue and fibrin only) were statistically insignificant. Conclusion:The use of a T-handle Jamshidi needle with an acquisition cradle appears beneficial compared to the conventional Jamshidi needle in terms of the significantly higher rate of diagnostic success and a lower rate of crush artifact.

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Percutaneous Image-Guided Spinal Lesion Biopsies: Factors Affecting Higher Diagnostic Yield

Abstract: For percutaneous image-guided biopsies of spinal tumorous lesions, diagnostic yield was 80%. Size, bone matrix, and final diagnosis of lesions affected diagnostic yield of percutaneous image-guided biopsies.

Cited by 23 publications

References 24 publications

Imaging-guided percutaneous vertebral and paravertebral lesion biopsy: A single center experience

Imaging-guided percutaneous vertebral and paravertebral lesion biopsy: A single center experience

Computed Tomography-Guided Vertebral Biopsy in Suspected Tuberculous Spondylodiscitis: Comparing a New Navigational Tram-Track Technique versus Conventional Method

Comparative analysis of CT guided vertebral biopsy by a conventional bone biopsy needle versus bone biopsy needle with acquisition cradle

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