Percutaneous image-guided cryoablation of painful bone metastases: A single institution experience

Gallusser, Nicolas; Goetti, Patrick; Becce, Fabio; Vauclair, Frédéric; Rüdiger, Hannes A.; Bize, Pierre; Cherix, Stéphane

doi:10.1016/j.otsr.2019.01.001

Cited by 18 publications

(7 citation statements)

References 38 publications

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“…Percutaneous ablation has been shown to produce favorable outcomes for local pain control. 11,21 Gallusser et al, 26 showed a 75% improvement in pain score rating using a similar method as the one demonstrated, and Goetz et al 9 has showed improvement in VAS scores in 95% of his cohort, and notable reduction of opioid consumption. The present study reinforces previous literature of successful local pain control as demonstrated by the 100% VAS score improvement.…”

Section: Discussionmentioning

confidence: 89%

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Favorable outcomes of navigated percutaneous ablation and cementoplasty of bone metastasis in the extremities and pelvis-a case series of 13 cases

Efrima

Benady²,

Ovadia

et al. 2023

J Orthop Surg (Hong Kong)

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Objectives Palliative treatment options for bone metastasis are limited, especially in cases where standard protocols have already failed. The purpose of this study was to evaluate the efficacy and safety of percutaneous ablation, either by cryoablation or radiofrequency, combined with percutaneous cementoplasty using cone-beam guided navigation. The objective was to relieve symptoms and improve functionality in patients suffering from pain secondary to bone metastases, as well as evaluate local disease progression post ablation. Methods We conducted a retrospective study of 13 patients (average age 63.6 ± 9.8, nine females) with symptomatic skeletal metastases treated using 3D imaging with navigation and followed for at least 12 months. The treatment protocol was implemented either after failure of first line treatment, or as first line when mechanical instability was present. Percutaneous lesion ablation was performed along with percutaneous cementation. Results In this study, we observed a statistically significant decrease in pain. The mean Visual Analog Scale pain score decreased from 7.1 ± 0.4 prior to CRA/RFA to 2.2 ± 0.3 after the procedure ( p < 0.001). At the 12-months follow-up, all patients were able to ambulate with no assistance (Eastern Cooperative Oncology Group <2). One minor adverse event (paresthesia) and one major adverse event (drop foot) were resolved at 1 year of follow-up. Conclusions Treatment of bone metastasis with RFA and CRA in conjunction with cementoplasty using Cone-beam computed tomography navigation provides patients with significant palliative outcomes and in most cases, local tumor control.

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Section: Discussionmentioning

confidence: 89%

“…and Gallusser et al They demonstrated local disease control in 63% and 68% of patients using percutaneous guided ablation, respectively. 26,29…”

Section: Discussionmentioning

confidence: 99%

Favorable outcomes of navigated percutaneous ablation and cementoplasty of bone metastasis in the extremities and pelvis-a case series of 13 cases

Efrima

Benady²,

Ovadia

et al. 2023

J Orthop Surg (Hong Kong)

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“…One of the consequences of bone necrosis induced by CA is the weakening of the bone structure, which predisposes the patient to delayed post-procedure fractures. For this reason, in patients affected by osteolytic metastatic disease at risk of fracture, especially in axial-loading sites as the periacetabular region or vertebral bodies, CA has successfully been associated with cementoplasty, which has demonstrated durable pain relief and stabilization [ 88 , 89 , 90 , 91 , 92 ]. Ferrer-Mileo et al [ 78 ] conducted a systematic review of 22 studies regarding the use of cryoablation to control cancer pain, reporting a mean pain score decrease by 62.5% at 24 h post-procedure, 70% at 3 months, and 80.9% at 6 months.…”

Section: Cryoablationmentioning

confidence: 99%

Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review

Papalexis¹,

Parmeggiani²,

Peta³

et al. 2022

Current Oncology

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Metastases are the main type of malignancy involving bone, which is the third most frequent site of metastatic carcinoma, after lung and liver. Skeletal-related events such as intractable pain, spinal cord compression, and pathologic fractures pose a serious burden on patients’ quality of life. For this reason, mini-invasive treatments for the management of bone metastases were developed with the goal of pain relief and functional status improvement. These techniques include embolization, thermal ablation, electrochemotherapy, cementoplasty, and MRI-guided high-intensity focused ultrasound. In order to achieve durable pain palliation and disease control, mini-invasive procedures are combined with chemotherapy, radiation therapy, surgery, or analgesics. The purpose of this review is to summarize the recently published literature regarding interventional radiology procedures in the treatment of cancer patients with bone metastases, focusing on the efficacy, complications, local disease control and recurrence rate.

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“…Percutaneous cementoplasty and cryotherapy have supplemented the arsenal for local control of the metastatic osteolysis, before or even in competition with the surgery [32][33][34]. The current standard of care for metastatic disease combined with recent progress in the control of primary tumors that spread to bone and bone destruction with osteolysis inhibitors and/or radiation therapy justify this national study [35][36][37][38][39][40].…”

Section: Introductionmentioning

confidence: 99%

Surgical treatment of peri-acetabular metastatic disease: Retrospective, multicentre study of 91 THA cases

Lavignac¹,

Prieur²,

Fabre³

et al. 2020

Orthopaedics & Traumatology: Surgery & Research

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Percutaneous image-guided cryoablation of painful bone metastases: A single institution experience

Cited by 18 publications

References 38 publications

Favorable outcomes of navigated percutaneous ablation and cementoplasty of bone metastasis in the extremities and pelvis-a case series of 13 cases

Favorable outcomes of navigated percutaneous ablation and cementoplasty of bone metastasis in the extremities and pelvis-a case series of 13 cases

Minimally Invasive Interventional Procedures for Metastatic Bone Disease: A Comprehensive Review

Surgical treatment of peri-acetabular metastatic disease: Retrospective, multicentre study of 91 THA cases

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