Percutaneous delivery of low-level laser energy reverses histamine-induced spasm in atherosclerotic Yucatan microswine.

Abstract

These findings document for the first time that light-induced relaxation of vascular smooth muscle, previously documented in vitro, may be reproduced in vivo.

The current status of low level laser therapy in dentistry, Part 1. Soft tissue applications

“…In in vitro systems, LLLT can induce a prompt reduction in isometric tension of vascular smooth muscle, while the same effect can be induced by LLLT in vivo delivered through the skin to the underlying vessels. 37 Relaxation of vascular smooth muscle may contribute to analgesic effects of LLLT.…”

Assessment of Changes in Carotid Blood Flow Following LLLT of the Neck

“…Total blood flow continued to drastically increase for 30 min post laser-irradiation, where it reached its plateau at a 200% increase (5) . The correlation between arterial blood flow and LLLT has been reported by Gal D. et al in 1992 where they used a porcine arterial sclerosis model and showed post-laser irradiation dilatation through angiography. At 3 min post-laser irradiation, the cross-sectional area of the common carotid artery, vessel diameter and blood flow volume of the laser irradiated side increased by 52%, 23% and 87% respectively.…”

Photodynamic therapy for rheumatoid arthritis?

“…It has been shown previously in angioplasty that 351 nm can be delivered via silica fibers [29]. Whereas for large joints, a conventional arthroscopic use is possible, for small joints the use of needlescopes can be taken into consideration that include a working channel for a laser fiber with an outer diameter of <1 mm.…”