Percutaneous cryoanalgesia in pain management: a case-series

Bellini, Martina; Barbieri, Massimo

doi:10.5603/ait.2015.0045

Cited by 11 publications

(6 citation statements)

References 14 publications

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“…The development of percutaneously inserted cryoprobes greatly increased possible analgesic applications because surgical exposure of the target nerve was no longer required. 6 Anatomic landmarks (blind) 62 and/or nerve stimulation initially guided probe insertion, 6,63 but these techniques were eventually supplemented/replaced with biplane X-rays, 64,65 fluoroscopy, 66,67 computed tomography, [67][68][69][70][71][72] magnetic resonance imaging, [73][74][75] and ultrasound. 76,77 Imaging not only improves nerve targeting, 78 but-most importantly-enables real-time evaluation of the ice ball's envelopment of the target nerve.…”

Section: Imagingmentioning

confidence: 99%

Cryoneurolysis and Percutaneous Peripheral Nerve Stimulation to Treat Acute Pain

Ilfeld¹,

Finneran²

2020

Anesthesiology

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Two regional analgesic modalities currently cleared by the U.S. Food and Drug Administration hold promise to provide postoperative analgesia free of many of the limitations of both opioids and local anesthetic-based techniques. Cryoneurolysis uses exceptionally low temperature to reversibly ablate a peripheral nerve, resulting in temporary analgesia. Where applicable, it offers a unique option given its extended duration of action measured in weeks to months after a single application. Percutaneous peripheral nerve stimulation involves inserting an insulated lead through a needle to lie adjacent to a peripheral nerve. Analgesia is produced by introducing electrical current with an external pulse generator. It is a unique regional analgesic in that it does not induce sensory, motor, or proprioception deficits and is cleared for up to 60 days of use. However, both modalities have limited validation when applied to acute pain, and randomized, controlled trials are required to define both benefits and risks.

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Section: Imagingmentioning

confidence: 99%

Cryoneurolysis and Percutaneous Peripheral Nerve Stimulation to Treat Acute Pain

Ilfeld¹,

Finneran²

2020

Anesthesiology

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“…Bellini and Barbieri [525,526] reported data from a series of cases with human patients suffering from chronic pain including sacroiliac pain and knee pain. The use of a cryoprobe to achieve cryoneurolysis resulted in a self-reported improvement in VAS pain scores by one month, with optimum results at 3 months.…”

Section: Cryoanalgesiamentioning

confidence: 99%

Analgesia for Sheep in Commercial Production: Where to Next?

Small

Fisher

et al. 2021

Animals

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Increasing societal and customer pressure to provide animals with ‘a life worth living’ continues to apply pressure on livestock production industries to alleviate pain associated with husbandry practices, injury and illness. Over the past 15–20 years, there has been considerable research effort to understand and develop mitigation strategies for painful husbandry procedures in sheep, leading to the successful launch of analgesic approaches specific to sheep in a number of countries. However, even with multi-modal approaches to analgesia, using both local anaesthetic and non-steroidal anti-inflammatory drugs (NSAID), pain is not obliterated, and the challenge of pain mitigation and phasing out of painful husbandry practices remains. It is timely to review and reflect on progress to date in order to strategically focus on the most important challenges, and the avenues which offer the greatest potential to be incorporated into industry practice in a process of continuous improvement. A structured, systematic literature search was carried out, incorporating peer-reviewed scientific literature in the period 2000–2019. An enormous volume of research is underway, testament to the fact that we have not solved the pain and analgesia challenge for any species, including our own. This review has highlighted a number of potential areas for further research.

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“…It involves the use of cold therapy on terminal nerves. 71,74 A study in rats demonstrated that degeneration occurred distal to the freezing site, with preservation of the overall anatomical structure. 75 Regeneration of nerve endings was shown to occur $6 weeks following therapy.…”

Section: Cryoneurolysismentioning

confidence: 99%

Pain Control in Total Knee Arthroplasty

et al. 2017

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As surgical techniques and pharmacology advance, the management of postoperative pain in patients undergoing total knee arthroplasty (TKA) continues to evolve. The current standards of care are composed of multimodal pain management including opioids, nonsteroidal anti-inflammatory drugs and gabapentinoids, peripheral nerve blocks, and periarticular injections. Newer modalities are composed of delayed release local anesthetics and cryoneurolysis. To summarize the current evidence-based treatment modalities and forecast changes in the management of patients having TKAs, we reviewed available data on: (1) oral analgesics; (2) periarticular injections; (3) peripheral nerve blocks; (4) multimodal regimens; and (5) newer modalities in post-TKA pain management. Multimodal analgesic regimens that target numerous pain pathways may provide the best pain management, rehabilitation, patient satisfaction, and reduce opioid use and related side effects. Periarticular injections of delayed-release local anesthetics may further enhance pain management.

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Percutaneous cryoanalgesia in pain management: a case-series

Cited by 11 publications

References 14 publications

Cryoneurolysis and Percutaneous Peripheral Nerve Stimulation to Treat Acute Pain

Cryoneurolysis and Percutaneous Peripheral Nerve Stimulation to Treat Acute Pain

Analgesia for Sheep in Commercial Production: Where to Next?

Pain Control in Total Knee Arthroplasty

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