Percutaneous computed tomography-guided core biopsy for the diagnosis of mediastinal masses

Kulkarni, Suyash; Kulkarni, Aniruddha; Roy, Diptiman; Thakur, Meenakshi

doi:10.4103/1817-1737.37948

Cited by 30 publications

(14 citation statements)

References 11 publications

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“…Reported accuracy rates of CT guided percutaneous needle aspiration/biopsy ranges from 64%-97% with a small risk of complications, and these results were observed by B Morrissey et al [1], Westcott JL et al [3]. Our study produced a better diagnostic yield as compared to other similar study conducted by Kulkarni et al who had reported a diagnostic yield of 96% [5].…”

Section: Discussioncontrasting

confidence: 53%

Incidence of Malignancy in Mediastinal Lymphadenopathy in Indian Population Using Ct Guided Biopsy as an Evaluating Tool

Vasanthraj¹,

Dev²,

Santosham³

et al. 2018

Int J Surg Med

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Causes of mediastinal lymphadenopathy are many, ranging from reactive lymphadenopathy to malignancy. With the high incidence of tuberculosis in India, we aimed to determine the incidence of malignancy in mediastinal nodes with no primary lung lesion using computed tomography (CT)-guided biopsy as an evaluating tool and highlighting the superiority of this procedure over others described in the literature.

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Section: Discussioncontrasting

confidence: 53%

Incidence of Malignancy in Mediastinal Lymphadenopathy in Indian Population Using Ct Guided Biopsy as an Evaluating Tool

Vasanthraj¹,

Dev²,

Santosham³

et al. 2018

Int J Surg Med

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“…[1314] Diagnostic yield was low (74.2%) for mediastinal procedures in our series where as in previous series, it is 83.6–96%. [1516]…”

Section: Discussionmentioning

confidence: 99%

“…[17] Fusion positron emission tomography-CT images of many patients were available in the series by Kulkarni et al ., which help in targeting the metabolically active portion of the lesion. [15] In many series, the biopsies were done by an experienced and dedicated operators while in our setup, some of the cases were done by a less experienced resident. Apart from these, the most important reason for the high diagnostic yield in other series was the availability of follow-up and a nonspecific benign pathology result was considered diagnostic if the lesion had a benign course.…”

Section: Discussionmentioning

confidence: 99%

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Percutaneous computed tomography-guided aspiration and biopsy of intrathoracic lesions: Results of 265 procedures

et al. 2016

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Context:Percutaneous computed tomography (CT)-guided needle aspiration and biopsy technique have developed over time as a method for obtaining tissue specimen. Although this is a minimally invasive procedure, complications do occasionally occur.Aims:The aim of the study was to evaluate the diagnostic yield and complications of 265 percutaneous CT-guided aspiration and biopsy procedures performed on various intrathoracic lesions.Settings and Design:Data of percutaneous CT-guided aspiration and biopsy procedures of intrathoracic lesions performed over a 4 year period were retrospectively analyzed.Subjects and Methods:Procedure details, radiological images, and pathological and microbiological reports were retrieved from radiology records and hospital information system. Technical success, diagnostic yield, and complication rates were calculated.Results:Total 265 procedures were performed for lung (n = 179), mediastinum (n = 73), and pleural lesions (n = 13). Diagnostic yield for lung, mediastinal, and pleural lesions was 80.7%, 74.2, and 75%, respectively, for core biopsy specimens. Major complication was noted in only one procedure (0.4%). Minor complications were noted in 13.6% procedures which could be managed conservatively.Conclusions:Percutaneous CT-guided aspiration and biopsy procedures for intrathoracic lesions are reasonably safe with good diagnostic yield. Complications are infrequent and conservatively managed in most of the cases.

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“…This technique under guidance of fluoroscopy, ultrasonography, or computed tomography (CT) allows sufficient tissue sampling for accurate histologic and immunohistochemical evaluation; thereby it could highlight the need for further mediastinoscopy, mediastinotomy, thoracoscopy, or open chest surgery. [ 1 2 3 4 ] Previous reports have been shown higher accuracy of histology in comparison with cytology in evaluation of mediastinal lesions. [ 3 4 5 ]…”

Section: Introductionmentioning

confidence: 99%

Computed tomography-guided percutaneous core needle biopsy for diagnosis of mediastinal mass lesions: Experience with 110 cases in two university hospitals in Isfahan, Iran

Rabbani

Sarrami

2016

Adv Biomed Res

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Background:Computed tomography-guided percutaneous core needle biopsy (PCNB) is a diagnostic technique for initial assessment of mediastinal mass lesions. This study was conducted to evaluate its diagnostic yield and its complication rate.Materials and Methods:We reviewed the records of CT-guided PCNB in 110 patients with mediastinal mass lesions performed in Kashani and Alzahra Hospitals, Isfahan, from 2006 to 2012. Gender, age at biopsy, size, and anatomic location of the lesion, number of passes, site of approach, complications, and final diagnosis were extracted.Results:Our series encompasses 52 (47.2%) females and 58 (52/7%) males with mean age of 41 ± 8 years. The most common site of involvement was the anterior mediastinum (91.8% of cases). An average of 3/5 passes per patient has been taken for tissue sampling. Parasternal site was the most frequent approach taken for PCNB (in 78.1% of cases). Diagnostic tissue was obtained in 99 (90%) biopsies while, in 11 (10%) cases, specimen materials were inadequate. Lymphoma (49.5%) and bronchogenic carcinoma (33.3%) were the most frequent lesions in our series. The overall complication rate was 17.2% from which 10.9% was pneumothorax, 5.4% was hemoptysis, and 0.9% was vasovagal reflex.Conclusion:CT-guided PCNB is a safe and reliable procedure that can provide a precise diagnosis for patients with both benign and malignant mediastinal masses, and it is considered the preferred first diagnostic procedure use for this purpose.

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Percutaneous computed tomography-guided core biopsy for the diagnosis of mediastinal masses

Cited by 30 publications

References 11 publications

Incidence of Malignancy in Mediastinal Lymphadenopathy in Indian Population Using Ct Guided Biopsy as an Evaluating Tool

Incidence of Malignancy in Mediastinal Lymphadenopathy in Indian Population Using Ct Guided Biopsy as an Evaluating Tool

Percutaneous computed tomography-guided aspiration and biopsy of intrathoracic lesions: Results of 265 procedures

Computed tomography-guided percutaneous core needle biopsy for diagnosis of mediastinal mass lesions: Experience with 110 cases in two university hospitals in Isfahan, Iran

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