Percutaneous aspiration thrombectomy for the treatment of acute lower extremity deep vein thrombosis: is thrombolysis needed?

Kwon, Se Hwan; Oh, Joo Hyeong; Seo, Tae Seok; Ahn, Hanjong; Park, H.C.

doi:10.1016/j.crad.2009.01.002

Cited by 34 publications

(29 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In our present study, vascular stenosis was detected in 90.4 % (n = 21) of patients who had undergone PAT. Similar to what was found in a previous study [13], the patency rates in patients with stents were 92.8 % at 1 month follow-up, and 85.7 % at 3 and 12 months (Table 4). In our present study, thrombosis developed during the early postoperative period in only one iliac and one femoral vein that were stented.…”

Section: First Monthsupporting

confidence: 89%

“…The incidence of venous stenosis was previously reported to be 85 % in patients with acute proximal DVT [13]. In our present study, vascular stenosis was detected in 90.4 % (n = 21) of patients who had undergone PAT.…”

Section: First Monthsupporting

confidence: 61%

“…However, few clinical studies have been performed. Kwon et al [13] reported a recanalisation rate of 88.9 % in 27 patients who had undergone PAT; no complication was noted. Mechanical thrombectomy devices are not required during PAT and, therefore, the risk of trauma to the vascular wall and valves is thought to be low.…”

Section: First Monthmentioning

confidence: 93%

“…Mechanical thrombectomy devices are not required during PAT and, therefore, the risk of trauma to the vascular wall and valves is thought to be low. Thrombolytic agents are not given to PAT patients, and the bleeding complications associated with systemic therapy are therefore absent [13]. No standardised PAT aspiration method has yet been developed.…”

Section: First Monthmentioning

confidence: 99%

See 3 more Smart Citations

Use of Percutaneous Aspiration Thrombectomy vs. Anticoagulation Therapy to Treat Acute Iliofemoral Venous Thrombosis: 1-year Follow-up Results of a Randomised, Clinical Trial

Çakır

Gülcü

Akay

et al. 2014

Cardiovasc Intervent Radiol

View full text Add to dashboard Cite

Purpose The purpose of this study was to compare the efficacy of percutaneous aspiration thrombectomy (PAT) followed by standard anticoagulant therapy, with anticoagulation therapy alone, for the treatment of acute proximal lower extremity deep vein thrombosis. Methods In this randomised, prospective study, 42 patients with acute proximal iliofemoral deep vein thrombosis documented via Doppler ultrasound examination, were separated into an interventional treatment group (16 males, 5 females, average age 51 years) and a medical treatment group (13 males, 8 females, average age 59 years). In the interventional group, PAT with largelumen 9-F diameter catheterisation was applied, after initiation of standard anticoagulant therapy. Balloon angioplasty (n 19) and stent implementation (n: 14) were used to treat patients with residual stenosis ([50 %) after PAT. Prophylactic IVC filters were placed in two patients. The thrombus clearance status of the venous system was evaluated by venography. In both the medical and interventional groups, venous patency rates and clinical symptom scores were evaluated at months 1, 3, and 12 after treatment.Results Deep venous systems became totally cleared of thrombi in 12 patients treated with PAT. The venous patency rates in month 12 were 57.1 and 4.76 % in the interventional and medical treatment groups, respectively. A statistically significant improvement was observed in clinical symptom scores of the interventional group (PAT) with or without stenting (4.23 ± 0.51 before treatment; 0.81 ± 0.92 at month 12) compared with the medical treatment group (4.00 ± 0.63 before treatment; 2.43 ± 0.67 at month 12). During follow-up, four patients in the medical treatment and one in the interventional group developed pulmonary embolisms. Conclusions For treatment of acute deep vein thrombosis, PAT with or without stenting is superior to anticoagulant therapy alone in terms of both ensuring venous patency and improving clinical symptoms. PAT is a safe, inexpensive, and easily performed method of endovascular treatment

show abstract

Section: First Monthsupporting

confidence: 89%

Section: First Monthsupporting

confidence: 61%

Section: First Monthmentioning

confidence: 93%

Section: First Monthmentioning

confidence: 99%

See 2 more Smart Citations

Use of Percutaneous Aspiration Thrombectomy vs. Anticoagulation Therapy to Treat Acute Iliofemoral Venous Thrombosis: 1-year Follow-up Results of a Randomised, Clinical Trial

Çakır

Gülcü

Akay

et al. 2014

Cardiovasc Intervent Radiol

View full text Add to dashboard Cite

show abstract

“…Recently, percutaneous thrombectomy methods alone or combined with CDT have been widely used as an effective endovascular method for thrombus removal. Compared with CDT, percutaneous thrombectomy methods are able to remove the thrombus more rapidly without the risk of bleeding complication (17,(20)(21)(22)(23)(24)(26)(27)(28)(29). Vedantham et al (20) found that the use of adjunctive percutaneous mechanical thrombectomy to augment CDT provides comparable procedural success and may reduce thrombolytic dose requirements and infusion times.…”

Section: Discussionmentioning

confidence: 99%

Endovascular treatment of iliofemoral deep vein thrombosis in pregnancy using US-guided percutaneous aspiration thrombectomy

Gedikoglu¹,

Oğuzkurt²

2017

Diagn Interv Radiol

View full text Add to dashboard Cite

P regnancy is a risk factor for venous thromboembolism (VTE) and the risk is highest in the postpartum period (1, 2). Anticoagulants are very effective in the prevention of pulmonary embolism (PE) and recurrent thrombosis, but the treatment of deep vein thrombosis (DVT) remains a challenge, because lysis of the thrombus formed in the deep veins is slow and frequently inadequate as a therapy (3, 4). Complete or significant lysis occurs only in 4% of patients treated with heparin alone (3). Persistence of thrombus within deep veins leads to venous hypertension, which is ultimately the cause of post-thrombotic syndrome (PTS) and late disability in 20% to 50% of patients. PTS is a conglomerate of lifestyle-limiting symptoms that commonly includes chronic leg pain and swelling, heaviness, and/or fatigue, venous claudication, stasis dermatitis, and in advanced cases skin ulcerations due to valvular incompetence accompanied by persistent venous outflow obstruction (4-8). Pregnant women are generally younger than other women in the general population, and they likely suffer a more severe form of PTS for a much longer time.Anticoagulants have been the standard therapy of DVT in pregnant women because of concerns related to administering contrast agent, exposing the fetus to radiation during interventional radiologic procedures, and bleeding complication associated with thrombolysis (9). Nonetheless, there are a few publications describing thrombolytic therapy of DVT with good success during pregnancy and peri-or postpartum period (10-13). In a previous study (14), a pregnant woman with DVT was treated using percutaneous mechanical thrombectomy under venographic guidance with contrast agent. Percutaneous aspiration thrombectomy (PAT) with or without fluoroscopy guidance in preg- 71From the Department of Radiology (M.G. 

show abstract

Deep Venous Thrombosis

Elsayed

2012

Vascular Surgery

View full text Add to dashboard Cite

Percutaneous aspiration thrombectomy for the treatment of acute lower extremity deep vein thrombosis: is thrombolysis needed?

Cited by 34 publications

References 25 publications

Use of Percutaneous Aspiration Thrombectomy vs. Anticoagulation Therapy to Treat Acute Iliofemoral Venous Thrombosis: 1-year Follow-up Results of a Randomised, Clinical Trial

Use of Percutaneous Aspiration Thrombectomy vs. Anticoagulation Therapy to Treat Acute Iliofemoral Venous Thrombosis: 1-year Follow-up Results of a Randomised, Clinical Trial

Endovascular treatment of iliofemoral deep vein thrombosis in pregnancy using US-guided percutaneous aspiration thrombectomy

Deep Venous Thrombosis

Contact Info

Product

Resources

About