Percutaneous Approach in Renal Lithiasis

Geavlete, P.; Georgescu, D.; Multescu, R.; Alexandrescu, Emanuel; Dragutescu, M.; Persu, C.; Moldoveanu, C.; Jecu, M.; Geavlete, B.

doi:10.1016/b978-0-12-802404-1.00003-7

Cited by 1 publication

(1 citation statement)

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“…Among these, the use of the Amplatz Renal Dilator in the treatment of urethral strictures represents a novel approach, diverging from traditional methods to offer a potentially less morbid solution (10,11). The Amplatz Renal Dilator, originally designed for facilitating renal access in percutaneous nephrolithotomy, has recently been repurposed in the urological field for the dilation of urethral strictures (12,13). Its unique design allows for gradual and controlled dilation, potentially minimizing the risk of urethral injury and subsequent scar formation, a common complication of other dilation techniques (14).…”

Section: Introductionmentioning

confidence: 99%

Use and Outcomes of Amplatz Renal Dilator for Treatment of Urethral Strictures

Mehmood,

Muhammad,

Patujo

et al. 2024

JHRR

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Background: Urethral strictures pose a significant challenge in urological practice, with traditional treatments often associated with considerable morbidity. The quest for less invasive yet effective interventions has led to innovative approaches, among which the Amplatz Renal Dilator has emerged as a promising tool. Objective: This study aimed to evaluate the efficacy and safety of the Amplatz Renal Dilator in the treatment of urethral strictures, focusing on urinary flow rates, stricture severity, patient symptom relief, and the incidence of complications. Methods: A prospective, observational cohort study was conducted at multiple centers including Gajju Khan Medical College Swabi Naseer Teaching Hospital Peshawar in the duration from January, 2023 to June, 2023. Total Thirty-five participants diagnosed with urethral strictures were enrolled and treated with the Amplatz Renal Dilator. The study spanned two years, with an initial six-month recruitment phase followed by an eighteen-month follow-up. Efficacy was assessed through improvements in urinary flow rates and stricture severity, while safety was evaluated by monitoring procedural complications and recurrences. Quality of life and patient satisfaction were also measured using validated questionnaires. Results: Post-treatment, urinary flow rates significantly improved from a mean of 10 mL/s (SD ± 2) to 15 mL/s (SD ± 3) (p<0.001). Stricture severity decreased from Grade 3 (SD ± 1) to Grade 1 (SD ± 1) (p<0.001). International Prostate Symptom Score (IPSS) from 22 (SD ± 4) to 10 (SD ± 3) (p<0.001). The incidence of immediate complications was 5%, with no significant long-term complications reported. The recurrence rate of strictures was observed at 10%. Conclusion: The Amplatz Renal Dilator demonstrates significant efficacy in improving urinary flow rates and reducing stricture severity, with minimal complications and a low recurrence rate. These findings suggest that the Amplatz Renal Dilator is a safe and effective option for the treatment of urethral strictures, warranting further investigation in larger, randomized controlled trials.

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