Percutaneous alcohol-based sclerotherapy in aneurysmal bone cyst in children and adolescents

Marie-Hardy, Laura; Sayed, Laila El; Alves, Alexandra; Brunelle, Françis; Ouchrif, Younès; Naggara, Olivier; Breton, Sylvain; Mascard, Éric; Glorion, Christophe; Pannier, Stéphanie

doi:10.1016/j.otsr.2019.12.024

Cited by 14 publications

(8 citation statements)

References 22 publications

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“…Age under 10, gender, involvement of the lower extremities, or lesions adjacent to open growth plates have all been suggested as possible risk factors for local recurrence after surgical intervention in the treatment of an ABC 21,26 . Our results show that patients under the age of 10 and females tend to have a higher local recurrence rate, but these findings were not statistically significant.…”

Section: Discussioncontrasting

confidence: 62%

Does cryotherapy decrease the local recurrence rate in the treatment of an aneurysmal bone cyst? A comparative assessment

Levanon,

Merose,

Segal

et al. 2024

Journal Orthopaedic Research

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IntroductionCurettage with or without the use of adjuvants is standard of care in treatment of an Aneurysmal Bone Cyst (ABC). Historically, our approach combined curettage, high speed burr drilling and cryo‐ablation. However, treatments varied based on age, tumor location and surgeon preference. We asked:(1) Does cryoablation in addition to curettage and burr drilling decrease the local recurrence rates? (2) Are there any risk factors for local recurrence rate? (3) Does cryoablation improve postsurgical functional outcomes in these patients?Materials and MethodsPatients treated for an ABC, between January 2006 and December 2019 were included in this retrospective analysis. Patient and surgical characteristics, such as age, gender, tumor location, type of treatment, time of follow‐up, recurrence rate and functional outcome measured by the MSTS93 score were compared between those treated with and without cryo‐ablation.ResultsBoth groups, without cryo‐ablation (n‐88) and with cryo‐ablation (n‐42), showed no significant difference in local recurrence rates (9.1% vs 7.1%, p‐0.553) and functional outcomes as measured by the MSTS 93 score (28.9 vs. 27.8, p‐0262). Risk factors analyzed did not significantly affect local recurrence risk, except for secondary ABC diagnosis (p=0.017). The cryo‐ablation group had a more extended follow‐up (45.6 vs 73.2 months, p<0.001), reflecting shift in practice over time.ConclusionsWe found no significant difference in local recurrence rate or functional outcome in patients treated with or without cryo‐ablation. Formal curettage with additional high‐speed burr drilling provides effective tumor control and favorable functional outcomes, negating the need for adjuvant cryo‐ablation.This article is protected by copyright. All rights reserved.

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Section: Discussioncontrasting

confidence: 62%

Does cryotherapy decrease the local recurrence rate in the treatment of an aneurysmal bone cyst? A comparative assessment

Levanon,

Merose,

Segal

et al. 2024

Journal Orthopaedic Research

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“…Percutaneous alcohol sclerotherapy is effective for the treatment of ABC in children, but the size, invasiveness, location, and age of the patients should be considered. [ 14 ] Li [ 15 ] reported a 57-year-old patient with a giant ABC secondary to a giant cell tumor of the finger bone who was finally treated with amputation of the fifth finger. Denosumab seems to be effective in relieving pain and improving nerves in ABCs, but it does not significantly reduce the actual recurrence rate and has potentially life-threatening side effects.…”

Section: Discussionmentioning

confidence: 99%

Autogenous fibula head transplantation for aneurysmal bone cyst of distal radius: A case report followed up for 7 years

Wen,

Kuang,

Jiang

et al. 2024

Medicine

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Rationale: Aneurysmal bone cyst (ABC) is a rare primary or secondary tumor that usually occurs in young women aged between 10 and 20 years, mostly in the long tubular bone and spine. However, there are no definite standards for its clinical treatment. To our knowledge, this is the first report of a young female patient with distal radius ABC who was successfully treated with tumor resection and autogenous fibular head transplantation. Patient concerns: A 28-year-old married Chinese young woman presented to our hospital with swelling and pain in her right wrist for 2 years and aggravation of wrist movement restriction for 1 week. Diagnoses: Pathological biopsy confirmed ABC. Interventions: We performed a pathological examination of the tumor on the right wrist and preliminarily confirmed the diagnosis of ABC. The right wrist joint was reconstructed by total surgical resection of the ABC tumor in the right wrist joint and autogenous fibular head transplantation. Outcomes: During follow-up within 7 years, good right wrist function was confirmed. The tumor did not recur, the swelling of the right wrist disappeared, the joint pain and limitation of movement significantly improved, and the function of the right wrist was not impaired in daily activities. Radiography showed that the fracture had healed. Lessons: Our results suggest that autofibular head transplantation is an effective treatment for reconstruction of wrist function in adult patients with ABC of the distal radius.

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“…[ 23 , 29 , 30 ] In a larger case series, Rastogi et al observed a lesion size reduction of 76.6% after a mean of 3 injections in 72 patients with ABCs treated with polidocanol [ 31 ], while Marie-Hardy et al reported a lesion size reduction in 85% in 55 ABCs treated with 96% ethanol in a mean of 1.7 injections. [ 32 ] We think that additional cavity reconstruction using injectable bone void fillers may be of particular benefit for minimally invasive treatments of recurrent benign bone lesions to further promote bone healing.…”

Section: Revisions After Surgical Treatmentmentioning

confidence: 99%

Treatment of benign bone lesions with an injectable biphasic bone substitute

Döring

Rentenberger

Kolb

et al. 2022

BMC Musculoskelet Disord

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Background Injectable biphasic ceramic bone substitutes (BCBSs) represent a modern alternative to conventional options for bone defect filling, as they further open the possibilities for percutaneous cavity reconstruction. Although recent studies have shown good surgical outcomes after treatment with BCBSs, mid-term follow-up data are still missing. Patients and methods Between 2013 and 2017, 18 patients were [1] treated with BCBS [2] for benign bone lesions and [3] had a complete set of retrospective information, including surgical protocols, imaging, patient dismission letters and outpatient clinic protocols, [4] with a minimum follow-up time of one year. Eleven patients received percutaneous surgery, while 7 patients had open curettage and BCBS filling. The median follow-up time was 36.5 (range 12–80) months. Results Local recurrence was reported in four patients. A distinctive bone remodelling pattern was noted on follow-up X-ray and magnetic resonance imaging showing a double-line phenomenon and continuously increasing cortical thickness one year after treatment in nine of thirteen patients. Regarding surgical complications, one patient suffered from a septic complication that required BCBS removal and lavage. One patient experienced superficial surgical site inflammation with redness and swelling, while two other patients had prolonged wound secretion. Conclusion In a limited case series, the studied BCBS demonstrated acceptable surgical outcomes. Initial wound leakage and recurrence seemed to be associated with percutaneous injection. Further studies are needed to compare recurrence and bone graft resorption after open and percutaneous bone cyst surgeries and to further evaluate postoperative surgical site inflammation, which appears self-limiting in most cases.

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Percutaneous alcohol-based sclerotherapy in aneurysmal bone cyst in children and adolescents

Cited by 14 publications

References 22 publications

Does cryotherapy decrease the local recurrence rate in the treatment of an aneurysmal bone cyst? A comparative assessment

Does cryotherapy decrease the local recurrence rate in the treatment of an aneurysmal bone cyst? A comparative assessment

Autogenous fibula head transplantation for aneurysmal bone cyst of distal radius: A case report followed up for 7 years

Treatment of benign bone lesions with an injectable biphasic bone substitute

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