Perception of cognitive function in older adults following coronary artery bypass surgery.

Khatri, Parinda; Babyak, Michael A.; Clancy, Carolina P.; Davis, Rebecca L.; Croughwell, Narda D.; Newman, Mark F.; Reves, J. G.; Mark, Daniel B.; Blumenthal, James A.

doi:10.1037/0278-6133.18.3.301

Cited by 50 publications

(61 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Studies correlating subjective reports with objective measures have shown conflicting results [24,25]. Other authors have advocated a return or greater reliance on clinical assessments [8,18].…”

Section: Diagnosis Of Pocdmentioning

confidence: 99%

See 1 more Smart Citation

A review of postoperative cognitive dysfunction and neuroinflammation associated with cardiac surgery and anaesthesia

Harten¹,

2012

View full text Add to dashboard Cite

SummaryPostoperative cognitive dysfunction is receiving increasing attention, particularly as it mainly affects the (growing) elderly population. Until recently, cognitive deficits after cardiac surgery were thought to be caused by physiological disturbances associated with the cardiopulmonary bypass technique. Although the technique of 'off-pump' coronary revascularisation may potentially be associated with improved outcome, long-term follow-up studies have failed to demonstrate a significant reduction in the incidence of postoperative cognitive dysfunction. The focus of research is thus shifting from cardiopulmonary bypass to other factors common to both techniques, such as surgery, anaesthesia and patient-related predisposing factors. Priming of the immune system by ageing and atherosclerosis may result in an exaggerated systemic and cerebral inflammatory response to cardiac surgery and anaesthesia, causing neuronal loss or dysfunction resulting in cognitive dysfunction. We briefly discuss the evidence for cardiopulmonary bypass-related neuronal injuries in adult cardiac surgery patients, and review the evidence that immune priming is a key factor in the pathogenesis of cognitive dysfunction after cardiac surgery.

show abstract

Section: Diagnosis Of Pocdmentioning

confidence: 99%

“…One of the problems of such subjective assessments of cognitive performance is that these may be influenced by depression [24]. Studies correlating subjective reports with objective measures have shown conflicting results [24,25].…”

Section: Diagnosis Of Pocdmentioning

confidence: 99%

A review of postoperative cognitive dysfunction and neuroinflammation associated with cardiac surgery and anaesthesia

Harten¹,

2012

View full text Add to dashboard Cite

show abstract

“…Depressive symptoms are commonly elevated prior to heart surgery Goyal, Idler, Krause, & Contrada, 2005;Khatri et al, 1999;Pirraglia, Peterson, WilliamsRusso, Gorkin, & Charlson, 1999) and are associated with female gender (Czajkowski et al, 1997), neuroticism (Duits et al, 1999), lower education level, life stress, and lower social support (Pirraglia et al, 1999). Anxiety is also common (Khatri et al, 1999;Phillips-Bute et al, 2003), with predictors that include female gender and neuroticism (Czajkowski et al, 1997;Phillips-Bute et al, 2003).…”

mentioning

confidence: 99%

“…Anxiety is also common (Khatri et al, 1999;Phillips-Bute et al, 2003), with predictors that include female gender and neuroticism (Czajkowski et al, 1997;Phillips-Bute et al, 2003). Presurgical interventions reduce distress, but this is not always accompanied by improvements in objective measures of surgical recovery (M. Johnston & Vogele, 1993).…”

mentioning

confidence: 99%

Psychosocial factors in heart surgery: Presurgical vulnerability and postsurgical recovery.

et al. 2008

View full text Add to dashboard Cite

Objective: Distress and low perceived social support were examined as indicators of psychosocial vulnerability in patients about to undergo heart surgery. Design: A total of 550 study patients underwent heart surgeries, including bypass grafting and valve procedures. Psychosocial interviews were conducted about five days before surgery, and biomedical data were obtained from hospital records. Main Outcome Measures: Sociodemographic, personality, religious, and biomedical factors were evaluated as predictors of psychosocial vulnerability, and all five sets of variables were evaluated as contributors to hospital length of stay (LOS). Results: Patients scoring higher on one or more indicator of presurgical psychosocial vulnerability were younger, more likely to be female, less likely to be married, less well educated, lower in dispositional optimism, higher in trait anger, and lower in religiousness. Older age, depression, low support, and low trait anger each showed an independent, prospective association with greater LOS, and several other predictors had prospective relationships with LOS that were statistically mediated by depression or perceived support. Conclusion: Evidence that multiple psychosocial factors may influence adaptation to heart surgery has implications for understanding and ameliorating presurgical distress and for improving postsurgical recovery.

show abstract

“…Previous authors have suggested a relationship between MC and emotional distress in patients with epilepsy (5-16) and similar results have been found in general medical conditions (25)(26)(27)(28). The novelty of this study is the delineation of MC in a large sample of patients with epilepsy using user-friendly standardised clinical instruments which can be adopted in any outpatient clinic in a real life setting.…”

Section: Discussionmentioning

confidence: 66%

Clinical correlates of memory complaints during AED treatment

et al. 2016

View full text Add to dashboard Cite

Objectives: To investigate clinical correlates of memory complaints (MC) during antiepileptic drug (AEDs) treatment in adults with epilepsy with special attention to the role of depression, using userfriendly standardised clinical instruments which can be adopted in any outpatient setting. Materials & methods:Data from a consecutive sample of adult outpatients with epilepsy assessed with the Neurological Disorder Depression Inventory for Epilepsy (NDDIE), the Adverse Event Profile (AEP) and the Emotional Thermometer (ET) were analysed.Results: From a total sample of 443 patients, 28.4% reported MC as "always" a problem. These patients were less likely to be seizure free (18.3% vs. 34.3%; p<0.001), had a high number of previous AED trials (4 vs. 3; p<0.001) and high AEP total scores (49 vs. 34.2; p<0.001). There was no correlation with specific AED type or combination. Depression was the major determinant with a 2-fold increased risk (95%CI 1.15-3.86; p=0.016). When depression was already known and under treatment, patients with MC were less likely to be in remission from depression despite antidepressant treatment (11.9% vs. 1.6% p<0.001). Among patients without depression, those reporting MC presented with significantly high scores for depression (3.3 vs. 2; t=3.07; p=0.003), anxiety (4.5 vs.2.7; t=4.43; p<0.001), anger (3 vs. 2; t=2.623; p=0.009) and distress (3.8 vs. 2.2; t=4.027; p<0.001) than those without MC.Conclusions: Depression has to be appropriately treated and full remission from depression should represent the ultimate goal as sub-threshold or residual mood and anxiety symptoms can contribute to MC.

show abstract

Perception of cognitive function in older adults following coronary artery bypass surgery.

Cited by 50 publications

References 21 publications

A review of postoperative cognitive dysfunction and neuroinflammation associated with cardiac surgery and anaesthesia

A review of postoperative cognitive dysfunction and neuroinflammation associated with cardiac surgery and anaesthesia

Psychosocial factors in heart surgery: Presurgical vulnerability and postsurgical recovery.

Clinical correlates of memory complaints during AED treatment

Contact Info

Product

Resources

About