Percentage of Infiltrating T Lymphocytes in Diffuse Large B-Cell Lymphoma Lymph Nodes Measured By Flow Cytometry Predicts Overall Survival and Provides Additional Prognostic Information When Combined with the R-IPI
Abstract:INTRODUCTION:
Recent studies have suggested that tumor microenviroment (TME) may play an important role in lymphomagenesis and tumor progression in non-Hodgkin lymphoma. Tumor-infiltrating lymphocytes and myeloid-derived cells could provide valuable prognostic information independent from tumor characteristics alone. In diffuse large B-cell lymphoma (DLBCL) several attempts have been made to capture prognostic variables associated with TME. Peripheral blood monocytes, lymphocytes and natural kil… Show more
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