Prostate cancer, the leading cancer among men, constitutes a serious public health problem worldwide. Its treatment and care require a multi-professional approach. This descriptive review was conducted to establish the role of the clinical nurse specialist in providing prostate cancer care. The CINAHL, MEDLINE, PubMed, Medscape, LILACS, BDENF, and Cochrane databases were searched to identify relevant publications up to September 2013 written in Portuguese, English, and Spanish, using the Electronic Information Access Program and Coordination for the Improvement of Higher Education Personnel (CAPES) Periodicals Portal in the search system of the