Perbedaan Penurunan Tekanan Darah Pasien Hipertensi Yang Diberikan Terapi Amlodipin Pada Pagi Hari Dan Malam Hari Di Puskesmas Bayanan Kabupaten Hulu Sungai Selatan

Abstract

Research on timing taking amlodipine drugs against decrease in blood pressure showed different results, that’s significant and insignificant effect. Research to identify differences in blood pressure reduction from hypertension patients given amlodipine drug therapy in the morning with night at Puskesmas Bayanan Hulu Sungai Selatan Regency. This research method is obsevasional descriptive with Pre and post test design. There are two groups this design, namely hypertension patients given amlodipine drug therapy in the morning and night, blood pressure measured before and after 10 days of observation, then compared between difference in the decrease in blood pressure of patients given amlodipine drug therapy in the morning and night. The results of respondents given amlodipine drug therapy in the morning experienced average decrease in blood for systole -13.67 mmHg and for diastole -6.33 mmHg. Meanwhile, those given amlodipine therapy at night experienced average decrease in blood for cystole -19 mmHg and for diastole -10.33 mmHg. Wilcoxon sigh test results for blood pressure systole values Asymp.sig. 0.007 and for diastole blood pressure values Asymp.sig. 0.003 or <0.05 which states hypothesis is accepted or there is difference between decrease in blood pressure of hypertension patients given amlodipine drug therapy in the morning and night.