Per-cell histone acetylation is associated with terminal differentiation in human T cells
Cheng Yang,
You Li,
Yaqiu Hu
et al.
Abstract:Background
Epigenetic remodeling at effector gene loci has been reported to be critical in regulating T cell differentiation and function. However, efforts to investigate underlying epigenetic mechanisms that control T cell behaviors have been largely hindered by very limited experimental tools, especially in humans.
Results
In this study, we employed a flow cytometric assay to analyze histone acetylation at single-cell level in human T cells. The … Show more
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