Peptides-carrageenan-xanthan gum: Printing mechanism and anti-oxidation under in vitro digestion

Zhan, Junqi; Yu, Wentao; Fu, Jingjing; Li, Gao-shang; Hu, Yaqin; Chen, Yuewen

doi:10.1016/j.fbio.2023.102546

Food Bioscience

2023

DOI: 10.1016/j.fbio.2023.102546

|View full text |Cite

Peptides-carrageenan-xanthan gum: Printing mechanism and anti-oxidation under in vitro digestion

Junqi Zhan

Wentao Yu

Jingjing Fu

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article5

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 5 publications

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Antioxidant synergistic anti‐inflammatory effect in the MAPK/NF‐κB pathway of peptide KGEYNK (KK‐6) from giant salamander (Andrias davidianus)

Zhan,

Wu,

et al. 2024

J Sci Food Agric

View full text Add to dashboard Cite

BACKGROUNDGiant salamander protein peptide is a peptide with rich functional properties. Giant salamander protein peptide KGEYNK (KK‐6) is a peptide with both antioxidant and anti‐inflammatory properties. The antioxidant and anti‐inflammatory mechanisms of KK‐6 are still unclear. When we studied the functional mechanism of KK‐6, we found that the antioxidant property of KK‐6 has a synergistic and promoting effect on anti‐inflammatory properties.RESULTSKK‐6 enhances cellular resistance to LPS via the MAPK/NF‐κB signaling pathway, leading to increased levels of inflammatory factors: interleukin‐1β (764.81 ng mL−1), interleukin‐6 (1.06 ng mL−1) and tumor necrosis factor‐α (4440.45 ng mL−1). KK‐6 demonstrates potent antioxidant properties by activating the Nrf2 signaling pathway, resulting in elevated levels of antioxidant enzymes (glutathione peroxidase: 0.03 μg mL−1; superoxide dismutase: 0.589 μg mL−1) and a reduction in the concentration of the oxidative product malondialdehyde (967.05 μg mL−1).CONCLUSIONOur findings highlight the great potential of KK‐6, a peptide extracted from giant salamander protein, as a remedy for intestinal inflammation. Through its dual role as an antioxidant and anti‐inflammatory agent, KK‐6 offers a promising avenue for alleviating inflammation‐related damage and oxidative stress. This study lays the foundation for further exploration of giant salamander products and highlights their importance in health and novel food development. © 2024 Society of Chemical Industry.

show abstract

Antioxidant synergistic anti‐inflammatory effect in the MAPK/NF‐κB pathway of peptide KGEYNK (KK‐6) from giant salamander (Andrias davidianus)

Zhan,

Wu,

et al. 2024

J Sci Food Agric

View full text Add to dashboard Cite

show abstract

Review on emerging trends and challenges in the modification of xanthan gum for various applications

Kumar,

Gihar

et al. 2024

Carbohydrate Research

View full text Add to dashboard Cite

Ca2+-nano starch-lutein endowed 3D printed surimi with antioxidation and mutual reinforcing transmembrane transport mechanisms via hepg2 and caco-2 cells model

Li,

Shi,

Zhan

et al. 2024

Food Research International

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Peptides-carrageenan-xanthan gum: Printing mechanism and anti-oxidation under in vitro digestion

Cited by 5 publications

References 32 publications

Antioxidant synergistic anti‐inflammatory effect in the MAPK/NF‐κB pathway of peptide KGEYNK (KK‐6) from giant salamander (Andrias davidianus)

Antioxidant synergistic anti‐inflammatory effect in the MAPK/NF‐κB pathway of peptide KGEYNK (KK‐6) from giant salamander (Andrias davidianus)

Review on emerging trends and challenges in the modification of xanthan gum for various applications

Ca2+-nano starch-lutein endowed 3D printed surimi with antioxidation and mutual reinforcing transmembrane transport mechanisms via hepg2 and caco-2 cells model

Contact Info

Product

Resources

About