Peptide-Based Biomaterials for Bone and Cartilage Regeneration
Kausik Kapat,
Sakshi Kumbhakarn,
Rahul Sable
et al.
Abstract:The healing of osteochondral defects (OCDs) that result from injury, osteochondritis, or osteoarthritis and bear lesions in the cartilage and bone, pain, and loss of joint function in middle- and old-age individuals presents challenges to clinical practitioners because of non-regenerative cartilage and the limitations of current therapies. Bioactive peptide-based osteochondral (OC) tissue regeneration is becoming more popular because it does not have the immunogenicity, misfolding, or denaturation problems ass… Show more
Extracellular matrix (ECM) elasticity remains a crucial parameter to determine the cell-material interactions (viz adhesion, growth and differentiation), cellular communication and migration that are very essential to tissue repair and...
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