Peptic Ulceration Some Hæmatological and Metabolic Consequences of Gastric Surgery

Jones, Charlotte; Cox, Eric; Cooke, W. T.; Williams, John A.; Meynell, M. J.; Stammers, F. A. R.

doi:10.1016/s0140-6736(62)90282-9

Cited by 62 publications

(5 citation statements)

References 25 publications

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“…The patients in the present study are derived from a period in which Billroth II gastrectomy had become generally accepted [8][9][10][11][12]. Later studies showed considerable sequelae [13][14][15] appearing in the early postoperative years, but only few have described the long-term (i.e., 20-30 years) results [16][17][18][19][20]. The operative complications and mortality rate were not higher than in other gastrectomy studies [9,18,19,[21][22][23], but these should be compared to less extensive procedures such as vagotomy [1,24].…”

Section: Discussionmentioning

confidence: 99%

Twenty‐five years after Billroth II gastrectomy for duodenal ulcer

Fischer¹

1984

World j. surg.

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One thousand twenty‐five patients underwent a Billroth II resection for duodenal ulcer between 1948 and 1956. The operative mortality rate was 2.4%. At follow‐up between 22 and 30 years later, 522 had died and 423 patients were traced. Recurrent ulcer appeared in 2.6% of the cases. Postgastrectomy symptoms occurred with the following frequency: dumping 10%, diarrhea 5%, vomiting 7%, and pain 4%. Anemia developed in 18%, hypoalbuminemia and hypocalcemia in 40 and 15%, respectively. Eleven percent had lost more than 10 kg in weight. Tuberculosis was found in 3% of the cases. While 90% of the patients were satisfied with the result, 10% were failures. The overall mortality rate was significantly increased because of suicide. Gastric carcinoma was the cause of death no more often than expected.

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Section: Discussionmentioning

confidence: 99%

Twenty‐five years after Billroth II gastrectomy for duodenal ulcer

Fischer¹

1984

World j. surg.

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“…When comparing their results with those from the series that we reported from Birmingham [1] and that of Charles Clarke and his colleagues [2], I think that one of the main differences was the extent of the gastric resection employed. The group of patients that we studied had all been subjected to what (in the absence of accurate direct measurement) was considered to be a 4/s gastrectomy.…”

Section: Invited Commentarymentioning

confidence: 88%

“…If we assume that the sample of 75% of the survivors is a true representation of the series as a whole, then the recorded results are much better than most reported series from public hospitals in the U.K. [1,2,5] and U.S.A. [6]. In particular, there is less malnutrition, less bile vomiting, less anemia, and no evidence of metabolic bone disease.…”

Section: Invited Commentarymentioning

confidence: 90%

Invited commentary

Alexander-Williams

1980

World j. surg.

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“…B12 deficiency in 14% of patients who had had this operation one to 12 years previously. Jones et al (1962) found a 57% incidence in patients operated on five to six years before, and Hines, Hoffbrand and Mollin (1967) reported an overall incidence of 20% in 292 patients with gastrectomies carried out one to 20 years previously.…”

Section: Discussionmentioning

confidence: 99%

Vitamin B12 deficiency following polya gastrectomy

Buxton¹,

Collins²,

Phillips

1977

Int J Clinical Practice

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Patients who had a Polya gastrectomy have been followed up on a regular basis from 1956 to the present time. Serum vit. B12, haemoglobin (Hb) and mean corpuscular volume (MCV) were measured on each patient.Forty-three patients have been followed up for at least 10 years. Of these 24 (56%) had become vitamin B12 deficient after 10 years, and others subsequently developed this deficiency between 10 and 15 years.None of the patients in this study presented with megaloblastic anaemia. The mean haemoglobin at the time of diagnosis of their vit. B12 deficiency was 13.5 g%. The mean MCV was 90 cu. mu. (N.R. 76-96 cu. mu.).The shortest interval after gastrectomy that any patient in this group presented with vit, B12 deficiency was 5t years and the mean time of onset was 9.8 years. This is later than previous reports have suggested.

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Peptic Ulceration Some Hæmatological and Metabolic Consequences of Gastric Surgery

Cited by 62 publications

References 25 publications

Twenty‐five years after Billroth II gastrectomy for duodenal ulcer

Twenty‐five years after Billroth II gastrectomy for duodenal ulcer

Invited commentary

Vitamin B12 deficiency following polya gastrectomy

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