People with obsessive-compulsive disorder often remain symptomatic following psychological treatment: A clinical significance analysis of manualised psychological interventions

A systematic review and meta-analysis on the effectiveness of exposure and response prevention therapy in the treatment of Obsessive-Compulsive Disorder

“…It was important to include studies that maintained sufficient therapist-patient contact since research has been inconclusive in determining the number of hours needed for treatment effect and, importantly, the therapist holds an essential role during treatment, particularly in maintaining motivation (Tolin et al, 2007;Pearcy et al, 2016). Previous reviews have included studies with a variety of ERP protocols and included ERP designs with limited therapist contact or exposure as homework only in one analysis (Ponniah et al, 2013;Fisher et al, 2020).…”

“…Further, ERP manifests advantages in terms of relapse; 12% compared with clomipramine 45-89% (Simpson et al, 2004;Abramowitz et al, 2009). Other types of psychotherapy, such as Cognitive Therapy (CT) also lead to treatment gains (Fisher et al, 2020). Comparisons of psychological therapies, though, have provided mixed results: some studies finding that ERP is more effective (Abramowitz et al, 2002;Fisher and Wells, 2005;Ponniah et al, 2013) and others that it is as effective (Gava et al, 2007;Rosaalcazar et al, 2008;Skapinakis et al, 2016) as other interventions.…”

Implementing routine outcome monitoring in the treatment of a patient with obsessive‐compulsive disorder

“…According to Mataix‐Cols et al (2019) it is currently unclear to what extent the receipt of evidence‐based treatments alone, which primarily focus on symptom reduction, is sufficient to reduce the risk of these adverse outcomes. As stated by Fisher et al (2020) almost 80% of OCD treated patients remain symptomatic, which entails that the efficacy of psychological interventions for patients with OCD must be enhanced. In these cases, the dysfunctionality conspired against the therapeutic success with a short‐term and focused intervention and a second therapeutic phase was deemed necessary to maintain improvement.…”

Long-term outcomes of a course of deep TMS for treatment-resistant OCD

“…With regards to cognitive behavioral therapy (CBT), there are mixed results. A recent large meta-analysis of twenty-four randomized controlled trials demonstrated no durability [5]. Another study found durability after one year [6].…”