Penurunan Penggunaan Antibiotik pada Pasien Anak dengan Demam

Abstract

Latar belakang

Optimizing antibiotic use in Indonesia: a systematic review and synthesis of current evidence to inform opportunities for intervention

“…A total of 13 reports reported data on the effect of AMS interventions, of which 11 in hospitals, 23,28,31,33,47,[86][87][88][89][90][91] 1 in primary care, 92 and 1 in community pharmacies 93 (Table 2). Twelve reports used a pre-post design, and one was a randomized controlled trial.…”

“…23,31,47,86,88,90,91 Studies that evaluated education and/or training interventions (5 reports) reported mixed effects on antibiotic consumption and prescribing appropriateness. 31,[87][88][89]92 The one study that evaluated antibiotic restriction with pre-approval found that consumption of restricted antibiotics decreased and of unrestricted narrow-spectrum antibiotics increased. 28 The one randomised study that evaluated the effect of a pharmacist counselling session of outpatient antibiotic users in community pharmacies found that self-reported antibiotic adherence was 311 significantly higher in the intervention group compared to the control group.…”

“…Studies that evaluated bundled interventions (4 reports) reported favourable effects on antibiotic consumption, prescribing appropriateness, guideline compliance, blood culture sampling, HAI rates, hand hygiene compliance, and mortality, although the authors of one study concluded that the multifaceted intervention had limited success, with a very important drawback being the absence of adequate microbiological diagnostics. 31,88,89,92 Studies that evaluated the implementation of antibiotic prescribing guidelines or clinical pathway (7 reports) reported mixed effects on antibiotic consumption and favourable effects on prescribing appropriateness. 23,31,47,86,88,90,91 Studies that evaluated education and/or training interventions (5 reports) reported mixed effects on antibiotic consumption and prescribing appropriateness.…”

“…31,88,89,92 Studies that evaluated the implementation of antibiotic prescribing guidelines or clinical pathway (7 reports) reported mixed effects on antibiotic consumption and favourable effects on prescribing appropriateness. 23,31,47,86,88,90,91 Studies that evaluated education and/or training interventions (5 reports) reported mixed effects on antibiotic consumption and prescribing appropriateness. 31,[87][88][89]92 The one study that evaluated antibiotic restriction with pre-approval found that consumption of restricted antibiotics decreased and of unrestricted narrow-spectrum antibiotics increased.…”

Gambaran Pemakaian Antibiotika Setelah Implementasi Pedoman Pemakaian Antibiotika di Bangsal Kenanga RSUD Arifin Achmad Provinsi Riau Periode Juni-Agustus 2016

“…Penggunaan antibiotika dinilai dengan melihat rekam medis pemberian antibiotika dan rekam medis pasien dengan mempertimbangkan kesesuaian diagnosis (gejala klinis dan hasil laboratorium), indikasi, regimen dosis, keamanan dan harga. 6,7 Berild dkk.meneliti penurunan penggunaan dan biaya antibiotika dengan penerapan pedoman penggunaan antibiotika di Rumah Sakit Universitas Aker di Oslo, Norwegia. Pada penelitian ini digunakan suatu pedoman yang digunakan untuk sebagai dasar pemakaian antibiotika untuk terapi dan profilaksis.Dari penelitian ini didapatkan penurunan yang signifikan yaitu sebanyak 11% penggunaan antibiotika selama dua tahun penelitian dilakukan.Penggunaan antibiotika spektrum luas menurun sebanyak 23%.…”