Pentose phosphate cleavage by Leuconostoc mesenteroides

Hurwitz, Jerard

doi:10.1016/0006-3002(58)90526-2

Cited by 65 publications

(27 citation statements)

References 15 publications

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“…The fission ofpentose phosphate into C2fragments and glyceraldehyde 3-phosphate is a quite commonly occurring reaction in micro -organisms (Hurwitz, 1958;Hollmann, 1961). This reaction is catalysed by phosphoketolase and leads to acetyl phosphate and glyceraldehyde 3-phosphate.…”

Section: Discussionmentioning

confidence: 99%

Importance of the pentose phosphate pathway for d-glucose catabolism in the obligatory aerobic yeast Rhodotorula gracilis

Höfer¹,

Brand²,

Deckner³

et al. 1971

Biochemical Journal

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u-Glucose catabolism of a phosphofructokinase-deficient yeast Rhodotorula gracilis has been studied. By using D-glucose specifically 14C-labelled at different positions and measuring the distribution of the label in various fractions of cell metabolism, the following results were found. 1. The pentose phosphate pathway, being the main pathway of D-glucose catabolism, simultaneously converts glucose molecules into pentose phosphates oxidatively by using two NADP-linked dehydrogenases and via the non-oxidative transketolase-transaldolase pathway.2. From the correlation of the '4CO2 liberation and the D-glucose consumption and from the fact that the pentose phosphate moiety in nucleic acids is almost equally labelled from D-[1-14C]-and D-[6-_4C]-glucose, it is concluded that of the glucose utilized about 80% undergoes transformation via the non-oxidative pentose phosphate pathway. Only about 20% of glucose is directly decarboxylated to pentose phosphate. 3. For further degradation it is postulated that the pentose phosphates are split into C2 fragments and glyceraldehyde 3-phosphates. 4. All three loci of oxidative decarboxylation appear to be effective in Rh. gracili., the oxidative part of the pentose phosphate pathway, the decarboxylation of pyruvate in the later part of the glycolytic pathway as well as the oxidation in the tricarboxylic acid cycle. 5. D-Glucose molecules taken up are only partially oxidized to C02: about four-fifths of each glucose molecule metabolized is incorporated into cell constituents. 6. The quantitative interrelations of the flUXes of D-glucose subunits along the catabolic pathways have been estimated and are discussed.

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Section: Discussionmentioning

confidence: 99%

Importance of the pentose phosphate pathway for d-glucose catabolism in the obligatory aerobic yeast Rhodotorula gracilis

Höfer¹,

Brand²,

Deckner³

et al. 1971

Biochemical Journal

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“…The high content of NADP in the heterofermentors is understandable in view of the now established fact that the process of hetrolactic fermentation involves hexose monophosphate pathway (17)(18)(19)(20), in which two NADP-dependent dehydrogenases are operating. The intracellular concentration of NAD in Lactobacillus plantarum was roughly estimated to be 5.7 x 10_3 M, a figure which obviously exceeds far the Km values of the known NAD dependent dehydrogenases operative in glycolysis.…”

Section: Discussionmentioning

confidence: 99%

Levels of Nicotinamide Nucleotide Coenzymes in Lactic Acid Bacteria

Takebe

Kitahara

1963

J. Gen. Appl. Microbiol.

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“…The structure and mechanism of transketolase have been extensively studied, 121) but the three-dimensional structure and reaction mechanism of phosphoketolase has long been enigmatic, although phosphoketolase was discovered more than 50 years ago. [122][123][124] Very recently, crystallization of phosphoketolase from Lactococcus lactis 125) and structure determination of a substrate-free form of XFPK from B. longum JCM1217 126) were reported. Our group also succeeded in crystallization 127) and structure determination 128) of XFPK from B. breve (Fig.…”

Section: Bifid Shuntmentioning

confidence: 99%

Unique Sugar Metabolic Pathways of Bifidobacteria

Fushinobu

2010

Bioscience, Biotechnology, and Biochemistry

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Pentose phosphate cleavage by Leuconostoc mesenteroides

Cited by 65 publications

References 15 publications

Importance of the pentose phosphate pathway for d-glucose catabolism in the obligatory aerobic yeast Rhodotorula gracilis

Importance of the pentose phosphate pathway for d-glucose catabolism in the obligatory aerobic yeast Rhodotorula gracilis

Levels of Nicotinamide Nucleotide Coenzymes in Lactic Acid Bacteria

Unique Sugar Metabolic Pathways of Bifidobacteria

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